SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dkx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 3dkx REPLICATION PROTEIN
REPB
(Streptococcus
agalactiae) 		4 / 8 PHE A  11
LEU A  13
LEU A  78
LEU A  29
 None
 1.00A 2bfpC-3dkxA:
undetectable		 2bfpC-3dkxA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 3dkx REPLICATION PROTEIN
REPB
(Streptococcus
agalactiae) 		4 / 8 PHE A  11
LEU A  13
LEU A  78
LEU A  29
 None
 1.00A 2bfpD-3dkxA:
undetectable		 2bfpD-3dkxA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3dkx REPLICATION PROTEIN
REPB
(Streptococcus
agalactiae) 		3 / 3 ALA A  68
ARG A  72
LYS A  76
 None
 0.75A 3kp5B-3dkxA:
undetectable		 3kp5B-3dkxA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3dkx REPLICATION PROTEIN
REPB
(Streptococcus
agalactiae) 		5 / 12 MET A  33
ILE A  75
VAL A  71
LEU A  84
LEU A  13
 None
 0.97A 4o1zA-3dkxA:
undetectable		 4o1zA-3dkxA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 3dkx REPLICATION PROTEIN
REPB
(Streptococcus
agalactiae) 		4 / 6 LEU A  26
GLU A  27
ASN A 124
MET A  33
 None
 0.93A 4ww7A-3dkxA:
undetectable		 4ww7A-3dkxA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 3dkx REPLICATION PROTEIN
REPB
(Streptococcus
agalactiae) 		4 / 7 TYR A  56
ILE A  35
MET A  33
ILE A  75
 None
 0.84A 5murB-3dkxA:
undetectable		 5murB-3dkxA:
22.52