SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dkz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9Q_A_CHDA459_0 (ESTROGEN-RELATED RECEPTOR GAMMA)	3dkz	THIOESTERASE SUPERFAMILY PROTEIN (Bordetella parapertussis)	4 / 6	ASP A 123 LEU A 124 VAL A 125 ILE A 126	None	0.88A	1s9qA-3dkzA: undetectable	1s9qA-3dkzA: 22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUC_A_SAMA303_0 (CATECHOL O-METHYLTRANSFERASE)	3dkz	THIOESTERASE SUPERFAMILY PROTEIN (Bordetella parapertussis)	5 / 12	MET A 112 ASN A 113 GLU A 141 GLY A 142 ILE A 126	None	1.16A	4xucA-3dkzA: undetectable	4xucA-3dkzA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LSA_A_SAMA303_0 (CATECHOL O-METHYLTRANSFERASE)	3dkz	THIOESTERASE SUPERFAMILY PROTEIN (Bordetella parapertussis)	5 / 12	MET A 112 ASN A 113 GLU A 141 GLY A 142 ILE A 126	None	1.14A	5lsaA-3dkzA: undetectable	5lsaA-3dkzA: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YW0_A_ACTA411_0 (UNCHARACTERIZED PROTEIN KDOO)	3dkz	THIOESTERASE SUPERFAMILY PROTEIN (Bordetella parapertussis)	3 / 3	LYS A 154 LEU A 151 ARG A 145	None	0.77A	5yw0A-3dkzA: undetectable	5yw0A-3dkzA: 17.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1S9Q_A_CHDA459_0","ESTROGEN-RELATED RECEPTOR GAMMA","3dkz","THIOESTERASE SUPERFAMILY PROTEIN","Bordetella parapertussis",4,"ASP A 123;LEU A 124;VAL A 125;ILE A 126","None","0.88A","1s9qA-3dkzA:undetectable","1s9qA-3dkzA:22.08"],["4XUC_A_SAMA303_0","CATECHOL O-METHYLTRANSFERASE","3dkz","THIOESTERASE SUPERFAMILY PROTEIN","Bordetella parapertussis",5,"MET A 112;ASN A 113;GLU A 141;GLY A 142;ILE A 126","None","1.16A","4xucA-3dkzA:undetectable","4xucA-3dkzA:21.59"],["5LSA_A_SAMA303_0","CATECHOL O-METHYLTRANSFERASE","3dkz","THIOESTERASE SUPERFAMILY PROTEIN","Bordetella parapertussis",5,"MET A 112;ASN A 113;GLU A 141;GLY A 142;ILE A 126","None","1.14A","5lsaA-3dkzA:undetectable","5lsaA-3dkzA:22.52"],["5YW0_A_ACTA411_0","UNCHARACTERIZED PROTEIN KDOO","3dkz","THIOESTERASE SUPERFAMILY PROTEIN","Bordetella parapertussis",3,"LYS A 154;LEU A 151;ARG A 145","None","0.77A","5yw0A-3dkzA:undetectable","5yw0A-3dkzA:17.50"]]