SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dlv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 3dlv SIGNAL RECOGNITION
PARTICLE 19 KDA
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 ARG B  17
ARG B  25
PRO B  24
 None
 1.03A 2wljA-3dlvB:
undetectable		 2wljA-3dlvB:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 3dlv SIGNAL RECOGNITION
PARTICLE 19 KDA
PROTEIN
(Pyrococcus
furiosus) 		5 / 11 VAL B  74
ILE B  88
LYS B  86
SER B  84
SER B  82
 None
 1.27A 3bjwB-3dlvB:
undetectable		 3bjwB-3dlvB:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3dlv SIGNAL RECOGNITION
PARTICLE 19 KDA
PROTEIN
(Pyrococcus
furiosus) 		4 / 6 LEU B  87
ILE B  88
LEU B  44
GLU B  43
 None
 0.81A 4w5nA-3dlvB:
undetectable		 4w5nA-3dlvB:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 3dlv SIGNAL RECOGNITION
PARTICLE 19 KDA
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 ARG B  98
LYS B  91
GLU B  94
 None
 0.70A 5d0yA-3dlvB:
undetectable		 5d0yA-3dlvB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 3dlv SIGNAL RECOGNITION
PARTICLE 19 KDA
PROTEIN
(Pyrococcus
furiosus) 		4 / 5 ILE B  37
PHE B  46
SER B  84
ALA B  40
 None
 1.24A 5msdA-3dlvB:
undetectable		 5msdA-3dlvB:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 3dlv SIGNAL RECOGNITION
PARTICLE 19 KDA
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 VAL B  51
GLU B  52
ILE B  73
 None
 0.66A 6f7lB-3dlvB:
undetectable		 6f7lB-3dlvB:
14.52