SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dm3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3dm3 REPLICATION FACTOR A
(Methanocaldococc
us
jannaschii) 		4 / 7 ARG A  80
GLY A  82
THR A  57
GLU A  88
 None
NA  A 901 (-3.5A)
None
None
 0.91A 5bs8A-3dm3A:
undetectable
5bs8C-3dm3A:
undetectable
5bs8D-3dm3A:
undetectable		 5bs8A-3dm3A:
13.06
5bs8C-3dm3A:
13.06
5bs8D-3dm3A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3dm3 REPLICATION FACTOR A
(Methanocaldococc
us
jannaschii) 		4 / 7 ARG A  80
GLY A  82
THR A  57
GLU A  88
 None
NA  A 901 (-3.5A)
None
None
 0.89A 5btaA-3dm3A:
undetectable
5btaC-3dm3A:
undetectable
5btaD-3dm3A:
undetectable		 5btaA-3dm3A:
13.06
5btaC-3dm3A:
13.06
5btaD-3dm3A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3dm3 REPLICATION FACTOR A
(Methanocaldococc
us
jannaschii) 		4 / 6 ARG A  80
GLY A  82
THR A  57
GLU A  88
 None
NA  A 901 (-3.5A)
None
None
 0.92A 5btaA-3dm3A:
undetectable
5btaB-3dm3A:
undetectable
5btaC-3dm3A:
undetectable		 5btaA-3dm3A:
13.06
5btaB-3dm3A:
19.29
5btaC-3dm3A:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3dm3 REPLICATION FACTOR A
(Methanocaldococc
us
jannaschii) 		4 / 6 ARG A  80
GLY A  82
THR A  57
GLU A  88
 None
NA  A 901 (-3.5A)
None
None
 0.89A 5btcA-3dm3A:
undetectable
5btcC-3dm3A:
undetectable
5btcD-3dm3A:
undetectable		 5btcA-3dm3A:
13.06
5btcC-3dm3A:
13.06
5btcD-3dm3A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3dm3 REPLICATION FACTOR A
(Methanocaldococc
us
jannaschii) 		4 / 7 ARG A  80
GLY A  82
THR A  57
GLU A  88
 None
NA  A 901 (-3.5A)
None
None
 0.94A 5btfA-3dm3A:
undetectable
5btfB-3dm3A:
undetectable
5btfC-3dm3A:
undetectable		 5btfA-3dm3A:
13.06
5btfB-3dm3A:
19.29
5btfC-3dm3A:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3dm3 REPLICATION FACTOR A
(Methanocaldococc
us
jannaschii) 		4 / 6 ARG A  80
GLY A  82
THR A  57
GLU A  88
 None
NA  A 901 (-3.5A)
None
None
 0.96A 5btgA-3dm3A:
undetectable
5btgB-3dm3A:
undetectable
5btgC-3dm3A:
undetectable		 5btgA-3dm3A:
13.06
5btgB-3dm3A:
19.29
5btgC-3dm3A:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3dm3 REPLICATION FACTOR A
(Methanocaldococc
us
jannaschii) 		4 / 7 ARG A  80
GLY A  82
THR A  57
GLU A  88
 None
NA  A 901 (-3.5A)
None
None
 0.90A 5btgA-3dm3A:
undetectable
5btgC-3dm3A:
undetectable
5btgD-3dm3A:
undetectable		 5btgA-3dm3A:
13.06
5btgC-3dm3A:
13.06
5btgD-3dm3A:
19.29