SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dm8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 3dm8 UNCHARACTERIZED
PROTEIN RPA4348
(Rhodopseudomonas
palustris) 		4 / 4 VAL A  88
LEU A  25
ILE A  28
LEU A 116
 None
 0.83A 2byoA-3dm8A:
undetectable		 2byoA-3dm8A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_D_MTXD615_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3dm8 UNCHARACTERIZED
PROTEIN RPA4348
(Rhodopseudomonas
palustris) 		5 / 12 VAL A  88
LEU A 128
LEU A  92
ILE A  63
LEU A  17
 None
 1.04A 3hj3D-3dm8A:
undetectable		 3hj3D-3dm8A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 3dm8 UNCHARACTERIZED
PROTEIN RPA4348
(Rhodopseudomonas
palustris) 		4 / 7 PHE A  44
PHE A  46
PHE A  47
LEU A 123
 None
 0.87A 4ejgC-3dm8A:
undetectable		 4ejgC-3dm8A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_B_MTXB603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3dm8 UNCHARACTERIZED
PROTEIN RPA4348
(Rhodopseudomonas
palustris) 		5 / 12 VAL A  88
LEU A 128
LEU A  92
ILE A  63
LEU A  17
 None
 1.14A 4ky8B-3dm8A:
undetectable		 4ky8B-3dm8A:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_D_MTXD603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3dm8 UNCHARACTERIZED
PROTEIN RPA4348
(Rhodopseudomonas
palustris) 		5 / 12 VAL A  88
LEU A 128
LEU A  92
ILE A  63
LEU A  17
 None
 1.14A 4ky8D-3dm8A:
undetectable		 4ky8D-3dm8A:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 3dm8 UNCHARACTERIZED
PROTEIN RPA4348
(Rhodopseudomonas
palustris) 		3 / 3 ARG A 104
HIS A  73
ARG A  89
 None
 0.95A 5iaoC-3dm8A:
undetectable		 5iaoC-3dm8A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 3dm8 UNCHARACTERIZED
PROTEIN RPA4348
(Rhodopseudomonas
palustris) 		3 / 3 ARG A 104
HIS A  73
ARG A  89
 None
 0.91A 5iaoF-3dm8A:
undetectable		 5iaoF-3dm8A:
23.08