SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dmb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NOD_B_H4BB902_1 (NITRIC OXIDE SYNTHASE)	3dmb	PUTATIVE GENERAL STRESS PROTEIN 26 WITH A PNP-OXIDASE LIKE FOLD (Xanthomonas campestris)	3 / 3	ARG A 88 ILE A 48 TRP A 49	None	1.14A	1nodB-3dmbA: undetectable	1nodB-3dmbA: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NOD_B_H4BB902_1 (NITRIC OXIDE SYNTHASE)	3dmb	PUTATIVE GENERAL STRESS PROTEIN 26 WITH A PNP-OXIDASE LIKE FOLD (Xanthomonas campestris)	3 / 3	ARG A 88 ILE A 48 TRP A 49	None	1.09A	2nodB-3dmbA: undetectable	2nodB-3dmbA: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZM9_A_ACAA502_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	3dmb	PUTATIVE GENERAL STRESS PROTEIN 26 WITH A PNP-OXIDASE LIKE FOLD (Xanthomonas campestris)	4 / 8	ALA A 71 TRP A 130 GLY A 70 ILE A 69	None	0.86A	2zm9A-3dmbA: undetectable	2zm9A-3dmbA: 17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NW2_A_H4BA902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	3dmb	PUTATIVE GENERAL STRESS PROTEIN 26 WITH A PNP-OXIDASE LIKE FOLD (Xanthomonas campestris)	3 / 3	ARG A 88 ILE A 48 TRP A 49	None	1.10A	3nw2A-3dmbA: undetectable	3nw2A-3dmbA: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FR0_A_SAMA401_0 (ARSENIC METHYLTRANSFERASE)	3dmb	PUTATIVE GENERAL STRESS PROTEIN 26 WITH A PNP-OXIDASE LIKE FOLD (Xanthomonas campestris)	5 / 12	GLY A 70 GLY A 24 LEU A 87 ILE A 83 VAL A 21	None	1.02A	4fr0A-3dmbA: undetectable	4fr0A-3dmbA: 19.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NOD_B_H4BB902_1","NITRIC OXIDE SYNTHASE","3dmb","PUTATIVE GENERAL STRESS PROTEIN 26 WITH A PNP-OXIDASE LIKE FOLD","Xanthomonas campestris",3,"ARG A  88;ILE A  48;TRP A  49","None","1.14A","1nodB-3dmbA:undetectable","1nodB-3dmbA:16.99"],["2NOD_B_H4BB902_1","NITRIC OXIDE SYNTHASE","3dmb","PUTATIVE GENERAL STRESS PROTEIN 26 WITH A PNP-OXIDASE LIKE FOLD","Xanthomonas campestris",3,"ARG A  88;ILE A  48;TRP A  49","None","1.09A","2nodB-3dmbA:undetectable","2nodB-3dmbA:16.99"],["2ZM9_A_ACAA502_1","6-AMINOHEXANOATE-DIMER HYDROLASE","3dmb","PUTATIVE GENERAL STRESS PROTEIN 26 WITH A PNP-OXIDASE LIKE FOLD","Xanthomonas campestris",4,"ALA A  71;TRP A 130;GLY A  70;ILE A  69","None","0.86A","2zm9A-3dmbA:undetectable","2zm9A-3dmbA:17.15"],["3NW2_A_H4BA902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","3dmb","PUTATIVE GENERAL STRESS PROTEIN 26 WITH A PNP-OXIDASE LIKE FOLD","Xanthomonas campestris",3,"ARG A  88;ILE A  48;TRP A  49","None","1.10A","3nw2A-3dmbA:undetectable","3nw2A-3dmbA:16.99"],["4FR0_A_SAMA401_0","ARSENIC METHYLTRANSFERASE","3dmb","PUTATIVE GENERAL STRESS PROTEIN 26 WITH A PNP-OXIDASE LIKE FOLD","Xanthomonas campestris",5,"GLY A  70;GLY A  24;LEU A  87;ILE A  83;VAL A  21","None","1.02A","4fr0A-3dmbA:undetectable","4fr0A-3dmbA:19.03"]]