SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dmc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		4 / 7 ARG A 123
TYR A 122
PHE A  40
PHE A  32
 None
 0.97A 1e71M-3dmcA:
undetectable		 1e71M-3dmcA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		4 / 7 ARG A 123
TYR A 122
PHE A  40
PHE A  32
 None
 0.94A 1e72M-3dmcA:
undetectable		 1e72M-3dmcA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		4 / 7 ILE A  76
PHE A  91
PHE A 112
PHE A  32
 None
 1.21A 1e72M-3dmcA:
undetectable		 1e72M-3dmcA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		5 / 12 PHE A  63
PHE A  32
GLY A  16
GLY A  23
LEU A  24
 None
 1.09A 1fe2A-3dmcA:
undetectable		 1fe2A-3dmcA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		5 / 12 PHE A  63
PHE A  32
GLY A  16
GLY A  23
LEU A  24
 None
 1.05A 1igxA-3dmcA:
undetectable		 1igxA-3dmcA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		5 / 12 TYR A 122
LEU A  24
PHE A 112
PHE A  93
ILE A  76
 None
 1.39A 1xosA-3dmcA:
undetectable		 1xosA-3dmcA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		4 / 7 LEU A  36
PHE A  62
PHE A  32
ILE A 119
 None
 0.93A 2opxA-3dmcA:
undetectable		 2opxA-3dmcA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		4 / 7 LEU A 100
PHE A  99
TYR A  65
GLU A  68
 None
 0.96A 2vq5B-3dmcA:
undetectable		 2vq5B-3dmcA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		5 / 12 PHE A  63
PHE A  32
GLY A  16
GLY A  23
LEU A  24
 None
 1.01A 3hs6B-3dmcA:
undetectable		 3hs6B-3dmcA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		4 / 8 PHE A  40
GLY A 116
PHE A  20
PHE A  63
 None
 1.11A 3ko0B-3dmcA:
undetectable
3ko0J-3dmcA:
undetectable		 3ko0B-3dmcA:
23.19
3ko0J-3dmcA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		4 / 7 GLY A 116
PHE A  20
PHE A  63
PHE A  40
 None
 1.15A 3ko0L-3dmcA:
undetectable
3ko0N-3dmcA:
undetectable		 3ko0L-3dmcA:
23.19
3ko0N-3dmcA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		4 / 7 PHE A  40
GLY A 116
PHE A  20
PHE A  63
 None
 1.09A 3ko0K-3dmcA:
undetectable
3ko0S-3dmcA:
undetectable		 3ko0K-3dmcA:
23.19
3ko0S-3dmcA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		4 / 7 PHE A  40
GLY A 116
PHE A  20
PHE A  63
 None
 1.06A 3ko0R-3dmcA:
undetectable
3ko0T-3dmcA:
undetectable		 3ko0R-3dmcA:
23.19
3ko0T-3dmcA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		5 / 11 PHE A  44
GLY A  23
LEU A  24
PHE A  32
LEU A  33
 None
 1.09A 4wnuA-3dmcA:
undetectable		 4wnuA-3dmcA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		5 / 11 LEU A  36
SER A 121
VAL A  54
GLU A  61
ALA A  59
 None
 0.97A 5o96G-3dmcA:
undetectable		 5o96G-3dmcA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 3dmc NTF2-LIKE PROTEIN
(Trichormus
variabilis) 		5 / 10 MET A  46
THR A  41
PHE A  62
PHE A  63
VAL A  66
 None
 1.03A 6hu9C-3dmcA:
undetectable		 6hu9C-3dmcA:
16.43