SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dml'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PH9_D_GNTD301_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3dml	PUTATIVE UNCHARACTERIZED PROTEIN (Paracoccus denitrificans)	5 / 10	TRP A 19 THR A 30 TYR A 27 GLN A 26 ILE A 23	None	1.48A	2ph9D-3dmlA: 0.0 2ph9E-3dmlA: 0.0	2ph9D-3dmlA: 19.56 2ph9E-3dmlA: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3dml	PUTATIVE UNCHARACTERIZED PROTEIN (Paracoccus denitrificans)	4 / 7	THR A 30 TYR A 27 GLN A 26 ILE A 23	None	1.18A	2xytI-3dmlA: undetectable	2xytI-3dmlA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PEO_F_CU9F301_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3dml	PUTATIVE UNCHARACTERIZED PROTEIN (Paracoccus denitrificans)	4 / 6	THR A 30 TYR A 27 GLN A 26 ILE A 23	None	1.23A	3peoG-3dmlA: undetectable	3peoG-3dmlA: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PEO_J_CU9J301_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3dml	PUTATIVE UNCHARACTERIZED PROTEIN (Paracoccus denitrificans)	5 / 11	TRP A 19 THR A 30 TYR A 27 GLN A 26 ILE A 23	None	1.47A	3peoI-3dmlA: 0.0 3peoJ-3dmlA: 0.0	3peoI-3dmlA: 19.56 3peoJ-3dmlA: 19.56

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2PH9_D_GNTD301_1","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","3dml","PUTATIVE UNCHARACTERIZED PROTEIN","Paracoccus denitrificans",5,"TRP A  19;THR A  30;TYR A  27;GLN A  26;ILE A  23","None","1.48A","2ph9D-3dmlA:0.0;2ph9E-3dmlA:0.0","2ph9D-3dmlA:19.56;2ph9E-3dmlA:19.56"],["2XYT_H_TC9H1206_2","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","3dml","PUTATIVE UNCHARACTERIZED PROTEIN","Paracoccus denitrificans",4,"THR A  30;TYR A  27;GLN A  26;ILE A  23","None","1.18A","2xytI-3dmlA:undetectable","2xytI-3dmlA:20.00"],["3PEO_F_CU9F301_2","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","3dml","PUTATIVE UNCHARACTERIZED PROTEIN","Paracoccus denitrificans",4,"THR A  30;TYR A  27;GLN A  26;ILE A  23","None","1.23A","3peoG-3dmlA:undetectable","3peoG-3dmlA:19.56"],["3PEO_J_CU9J301_1","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","3dml","PUTATIVE UNCHARACTERIZED PROTEIN","Paracoccus denitrificans",5,"TRP A  19;THR A  30;TYR A  27;GLN A  26;ILE A  23","None","1.47A","3peoI-3dmlA:0.0;3peoJ-3dmlA:0.0","3peoI-3dmlA:19.56;3peoJ-3dmlA:19.56"]]