SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dmo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 3dmo CYTIDINE DEAMINASE
(Burkholderia
pseudomallei) 		4 / 8 ILE A  75
LEU A 103
GLU A 104
LEU A 107
 None
 0.83A 1eupA-3dmoA:
undetectable		 1eupA-3dmoA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 3dmo CYTIDINE DEAMINASE
(Burkholderia
pseudomallei) 		5 / 12 GLY A  40
LEU A  59
MET A  95
THR A 108
ILE A   7
 None
 1.30A 1p93B-3dmoA:
undetectable		 1p93B-3dmoA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 3dmo CYTIDINE DEAMINASE
(Burkholderia
pseudomallei) 		5 / 12 ALA A  58
GLY A  27
VAL A  26
VAL A 105
ILE A  75
 None
 0.89A 2f8gB-3dmoA:
undetectable		 2f8gB-3dmoA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 3dmo CYTIDINE DEAMINASE
(Burkholderia
pseudomallei) 		5 / 12 ALA A  58
GLY A  27
VAL A  26
VAL A 105
ILE A  75
 None
 0.89A 2o4lB-3dmoA:
undetectable		 2o4lB-3dmoA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 3dmo CYTIDINE DEAMINASE
(Burkholderia
pseudomallei) 		3 / 3 GLU A  44
VAL A  43
CYH A  51
 MRD  A 132 (-3.6A)
None
MRD  A 132 ( 4.6A)
 1.02A 3fbxA-3dmoA:
undetectable		 3fbxA-3dmoA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 3dmo CYTIDINE DEAMINASE
(Burkholderia
pseudomallei) 		5 / 9 ALA A  58
GLY A  27
VAL A  26
VAL A 105
ILE A  75
 None
 0.95A 3oxvA-3dmoA:
undetectable		 3oxvA-3dmoA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 3dmo CYTIDINE DEAMINASE
(Burkholderia
pseudomallei) 		5 / 10 ALA A  58
GLY A  27
VAL A  26
VAL A 105
ILE A  75
 None
 1.02A 3oxwD-3dmoA:
undetectable		 3oxwD-3dmoA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 3dmo CYTIDINE DEAMINASE
(Burkholderia
pseudomallei) 		5 / 11 ARG A  92
GLY A  27
VAL A  26
VAL A 105
ILE A  75
 None
 0.96A 3oxxB-3dmoA:
undetectable		 3oxxB-3dmoA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 3dmo CYTIDINE DEAMINASE
(Burkholderia
pseudomallei) 		5 / 11 ALA A  58
GLY A  27
VAL A  26
VAL A 105
ILE A  75
 None
 0.90A 3oxxD-3dmoA:
undetectable		 3oxxD-3dmoA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 3dmo CYTIDINE DEAMINASE
(Burkholderia
pseudomallei) 		5 / 11 ARG A  92
GLY A  27
VAL A  26
VAL A 105
ILE A  75
 None
 1.00A 3oxxD-3dmoA:
undetectable		 3oxxD-3dmoA:
23.61