SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dn7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 3dn7 CYCLIC NUCLEOTIDE
BINDING REGULATORY
PROTEIN
(Cytophaga
hutchinsonii) 		3 / 3 TRP A  77
VAL A  52
TRP A  78
 None
 1.44A 1gmkC-3dn7A:
undetectable
1gmkD-3dn7A:
undetectable		 1gmkC-3dn7A:
11.90
1gmkD-3dn7A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3dn7 CYCLIC NUCLEOTIDE
BINDING REGULATORY
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 8 GLU A 112
ARG A 117
ILE A 118
LEU A 121
 None
 0.81A 1jg4A-3dn7A:
undetectable		 1jg4A-3dn7A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3dn7 CYCLIC NUCLEOTIDE
BINDING REGULATORY
PROTEIN
(Cytophaga
hutchinsonii) 		5 / 12 PHE A  50
ASN A  48
LEU A 121
ILE A   6
LEU A  15
 None
 1.30A 1lhuA-3dn7A:
undetectable		 1lhuA-3dn7A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3dn7 CYCLIC NUCLEOTIDE
BINDING REGULATORY
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 8 TYR A  49
SER A  80
GLN A 111
ILE A 106
 None
 1.09A 2xz5B-3dn7A:
undetectable
2xz5E-3dn7A:
undetectable		 2xz5B-3dn7A:
21.59
2xz5E-3dn7A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 3dn7 CYCLIC NUCLEOTIDE
BINDING REGULATORY
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 8 TYR A 108
GLU A 112
SER A  80
ILE A  47
 None
 0.92A 3jz0B-3dn7A:
undetectable		 3jz0B-3dn7A:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 3dn7 CYCLIC NUCLEOTIDE
BINDING REGULATORY
PROTEIN
(Cytophaga
hutchinsonii) 		3 / 3 PHE A  12
LYS A 131
SER A 132
 None
 0.79A 3tyeB-3dn7A:
undetectable		 3tyeB-3dn7A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 3dn7 CYCLIC NUCLEOTIDE
BINDING REGULATORY
PROTEIN
(Cytophaga
hutchinsonii) 		3 / 3 TRP A  77
VAL A  52
TRP A  78
 None
 0.78A 3zq8C-3dn7A:
undetectable
3zq8D-3dn7A:
undetectable		 3zq8C-3dn7A:
11.90
3zq8D-3dn7A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 3dn7 CYCLIC NUCLEOTIDE
BINDING REGULATORY
PROTEIN
(Cytophaga
hutchinsonii) 		3 / 3 TYR A 129
TYR A 108
GLN A 111
 None
 1.09A 5jsdA-3dn7A:
undetectable
5jsdB-3dn7A:
undetectable		 5jsdA-3dn7A:
13.47
5jsdB-3dn7A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 3dn7 CYCLIC NUCLEOTIDE
BINDING REGULATORY
PROTEIN
(Cytophaga
hutchinsonii) 		3 / 3 TYR A 129
TYR A 108
GLN A 111
 None
 1.10A 5jsdB-3dn7A:
undetectable
5jsdC-3dn7A:
undetectable		 5jsdB-3dn7A:
13.47
5jsdC-3dn7A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3dn7 CYCLIC NUCLEOTIDE
BINDING REGULATORY
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 7 PHE A  50
LEU A 104
ALA A   4
GLN A 111
 None
 1.29A 6b89A-3dn7A:
undetectable		 6b89A-3dn7A:
16.33