SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dnh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 3dnh UNCHARACTERIZED
PROTEIN ATU2129
(Agrobacterium
fabrum) 		5 / 12 GLY A 109
VAL A  89
LEU A 147
MET A  81
LEU A  42
 None
 1.07A 1ya4B-3dnhA:
undetectable		 1ya4B-3dnhA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 3dnh UNCHARACTERIZED
PROTEIN ATU2129
(Agrobacterium
fabrum) 		4 / 4 LEU A 233
PRO A  63
ILE A 214
LEU A 224
 None
 1.04A 1ya4B-3dnhA:
undetectable		 1ya4B-3dnhA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 3dnh UNCHARACTERIZED
PROTEIN ATU2129
(Agrobacterium
fabrum) 		5 / 12 GLY A 109
VAL A  89
LEU A 147
MET A  81
LEU A  42
 None
 1.06A 1ya4C-3dnhA:
undetectable		 1ya4C-3dnhA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3dnh UNCHARACTERIZED
PROTEIN ATU2129
(Agrobacterium
fabrum) 		5 / 12 LEU A 107
LEU A 147
GLU A  62
GLY A  65
ASP A 220
 None
 1.06A 2bm9A-3dnhA:
undetectable		 2bm9A-3dnhA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 3dnh UNCHARACTERIZED
PROTEIN ATU2129
(Agrobacterium
fabrum) 		4 / 8 THR A 101
ARG A 104
PRO A 103
SER A  37
 None
 0.87A 3tzfB-3dnhA:
undetectable		 3tzfB-3dnhA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3dnh UNCHARACTERIZED
PROTEIN ATU2129
(Agrobacterium
fabrum) 		4 / 6 ARG A  31
GLY A 221
ASP A 220
ASP A 223
 None
 1.31A 5hp1A-3dnhA:
undetectable		 5hp1A-3dnhA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 3dnh UNCHARACTERIZED
PROTEIN ATU2129
(Agrobacterium
fabrum) 		5 / 12 ASP A 223
ILE A 114
THR A 215
ALA A  71
ALA A  40
 None
 1.23A 5vcgA-3dnhA:
undetectable		 5vcgA-3dnhA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 3dnh UNCHARACTERIZED
PROTEIN ATU2129
(Agrobacterium
fabrum) 		5 / 12 PHE A  69
ILE A  87
LEU A 147
ALA A  40
LEU A  91
 None
 1.37A 5zwrB-3dnhA:
undetectable		 5zwrB-3dnhA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 3dnh UNCHARACTERIZED
PROTEIN ATU2129
(Agrobacterium
fabrum) 		3 / 3 LYS A 208
SER A 226
SER A 228
 None
 1.10A 6gbfA-3dnhA:
undetectable		 6gbfA-3dnhA:
23.50