SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dni'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_2
(GLUCOCORTICOID
RECEPTOR)		 3dni DEOXYRIBONUCLEASE I
(Bos
taurus) 		4 / 5 LEU A 221
MET A 166
LEU A 165
GLN A 193
 None
 1.32A 1p93D-3dniA:
undetectable		 1p93D-3dniA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 3dni DEOXYRIBONUCLEASE I
(Bos
taurus) 		3 / 3 THR A 203
ASP A 168
GLU A  39
 CA  A 281 (-3.9A)
None
None
 0.81A 3qowA-3dniA:
undetectable		 3qowA-3dniA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3dni DEOXYRIBONUCLEASE I
(Bos
taurus) 		5 / 12 LEU A  81
ILE A  25
GLY A  12
ILE A   8
ALA A  47
 None
 0.85A 3uj7A-3dniA:
undetectable		 3uj7A-3dniA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3dni DEOXYRIBONUCLEASE I
(Bos
taurus) 		5 / 12 LEU A  81
ILE A  25
GLY A  12
ILE A   8
ALA A  47
 None
 0.85A 3uj7B-3dniA:
undetectable		 3uj7B-3dniA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3dni DEOXYRIBONUCLEASE I
(Bos
taurus) 		3 / 3 SER A 250
GLU A  78
GLU A 143
 None
 0.73A 4ymgB-3dniA:
2.6		 4ymgB-3dniA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dni DEOXYRIBONUCLEASE I
(Bos
taurus) 		4 / 7 ILE A  37
LEU A  81
ARG A  31
LEU A  55
 None
 0.96A 5b1aA-3dniA:
undetectable
5b1aJ-3dniA:
undetectable		 5b1aA-3dniA:
17.90
5b1aJ-3dniA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dni DEOXYRIBONUCLEASE I
(Bos
taurus) 		4 / 7 ILE A  37
LEU A  81
ARG A  31
LEU A  55
 None
 0.94A 5b3sA-3dniA:
undetectable
5b3sJ-3dniA:
undetectable		 5b3sA-3dniA:
17.90
5b3sJ-3dniA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3dni DEOXYRIBONUCLEASE I
(Bos
taurus) 		4 / 5 THR A 203
ALA A 204
THR A 205
HIS A 252
 CA  A 281 (-3.9A)
None
None
None
 0.96A 5ecmA-3dniA:
undetectable		 5ecmA-3dniA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3dni DEOXYRIBONUCLEASE I
(Bos
taurus) 		4 / 6 THR A 203
ALA A 204
THR A 205
HIS A 252
 CA  A 281 (-3.9A)
None
None
None
 0.86A 5ecoA-3dniA:
undetectable		 5ecoA-3dniA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 3dni DEOXYRIBONUCLEASE I
(Bos
taurus) 		3 / 3 THR A 203
ASP A 168
GLU A  39
 CA  A 281 (-3.9A)
None
None
 0.78A 5fa8A-3dniA:
1.6		 5fa8A-3dniA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3dni DEOXYRIBONUCLEASE I
(Bos
taurus) 		4 / 7 PHE A  11
VAL A  29
ILE A  25
VAL A  26
 None
 0.77A 5ik1A-3dniA:
undetectable		 5ik1A-3dniA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_1
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 3dni DEOXYRIBONUCLEASE I
(Bos
taurus) 		4 / 5 GLY A 100
ARG A  73
ASP A  98
GLN A 156
 None
 1.41A 5ubbA-3dniA:
undetectable		 5ubbA-3dniA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dni DEOXYRIBONUCLEASE I
(Bos
taurus) 		4 / 7 ILE A  37
LEU A  81
ARG A  31
LEU A  55
 None
 0.97A 5zcqA-3dniA:
undetectable
5zcqJ-3dniA:
undetectable		 5zcqA-3dniA:
17.90
5zcqJ-3dniA:
12.30