SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3do8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3do8 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 12 ILE A  45
ALA A  41
GLY A   7
LEU A  19
HIS A  13
 None
 1.30A 2a58B-3do8A:
3.0
2a58C-3do8A:
3.1		 2a58B-3do8A:
23.33
2a58C-3do8A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 3do8 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 12 ASP A  38
VAL A  58
ILE A  20
ILE A  75
ALA A  41
 None
 1.05A 3ohtA-3do8A:
undetectable
3ohtB-3do8A:
undetectable		 3ohtA-3do8A:
13.78
3ohtB-3do8A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 3do8 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Archaeoglobus
fulgidus) 		3 / 3 TYR A  79
LYS A 102
LYS A 106
 None
 1.13A 5dbyA-3do8A:
undetectable		 5dbyA-3do8A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 3do8 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 12 PHE A   9
LEU A   5
VAL A 120
SER A  93
GLU A  14
 None
 1.20A 5v1tA-3do8A:
undetectable		 5v1tA-3do8A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3do8 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 7 GLY A   7
THR A   8
PHE A   9
HIS A  16
 None
 0.49A 6jnhA-3do8A:
9.6		 6jnhA-3do8A:
25.97