SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3do9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3do9 UPF0302 PROTEIN
BA_1542/GBAA1542/BAS
1430
(Bacillus
anthracis) 		3 / 3 PHE A 103
PHE A  17
PHE A  13
 None
 0.88A 2od9A-3do9A:
undetectable		 2od9A-3do9A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 3do9 UPF0302 PROTEIN
BA_1542/GBAA1542/BAS
1430
(Bacillus
anthracis) 		4 / 7 HIS A 125
PRO A 123
HIS A  50
TYR A  53
 None
 1.17A 2ombC-3do9A:
undetectable
2ombD-3do9A:
undetectable		 2ombC-3do9A:
20.34
2ombD-3do9A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3do9 UPF0302 PROTEIN
BA_1542/GBAA1542/BAS
1430
(Bacillus
anthracis) 		3 / 3 PHE A 103
PHE A  17
PHE A  13
 None
 0.88A 2qqgA-3do9A:
undetectable		 2qqgA-3do9A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_B_GEOB1207_1
(DEOXYNUCLEOSIDE
KINASE)		 3do9 UPF0302 PROTEIN
BA_1542/GBAA1542/BAS
1430
(Bacillus
anthracis) 		5 / 12 ILE A  89
VAL A  45
MET A  60
ARG A  56
PHE A  72
 None
 1.35A 2vppB-3do9A:
undetectable		 2vppB-3do9A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3do9 UPF0302 PROTEIN
BA_1542/GBAA1542/BAS
1430
(Bacillus
anthracis) 		4 / 8 TYR A  98
ARG A  56
ILE A  89
GLU A 117
 None
 1.06A 4a97I-3do9A:
undetectable		 4a97I-3do9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 3do9 UPF0302 PROTEIN
BA_1542/GBAA1542/BAS
1430
(Bacillus
anthracis) 		3 / 3 ARG A 170
LEU A 171
GLU A 174
 None
 0.75A 4l3gF-3do9A:
undetectable		 4l3gF-3do9A:
18.73