SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dob'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 3dob HEAT SHOCK 70 KDA
PROTEIN F44E5.5
(Caenorhabditis
elegans) 		4 / 8 LEU A 400
MET A 519
GLU A 522
ALA A 523
 None
 0.75A 1a29A-3dobA:
undetectable		 1a29A-3dobA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3dob HEAT SHOCK 70 KDA
PROTEIN F44E5.5
(Caenorhabditis
elegans) 		5 / 12 HIS A 455
LYS A 512
LEU A 457
GLY A 446
MET A 519
 None
 1.20A 1d4fA-3dobA:
undetectable		 1d4fA-3dobA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3dob HEAT SHOCK 70 KDA
PROTEIN F44E5.5
(Caenorhabditis
elegans) 		5 / 12 HIS A 455
LYS A 512
LEU A 457
GLY A 446
MET A 519
 None
 1.18A 1d4fB-3dobA:
undetectable		 1d4fB-3dobA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3dob HEAT SHOCK 70 KDA
PROTEIN F44E5.5
(Caenorhabditis
elegans) 		5 / 12 HIS A 455
LYS A 512
LEU A 457
GLY A 446
MET A 519
 None
 1.11A 1d4fC-3dobA:
undetectable		 1d4fC-3dobA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3dob HEAT SHOCK 70 KDA
PROTEIN F44E5.5
(Caenorhabditis
elegans) 		5 / 12 HIS A 455
LYS A 512
LEU A 457
GLY A 446
MET A 519
 None
 1.18A 1d4fD-3dobA:
undetectable		 1d4fD-3dobA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 3dob HEAT SHOCK 70 KDA
PROTEIN F44E5.5
(Caenorhabditis
elegans) 		3 / 3 LEU A 543
PHE A 429
ARG A 534
 None
 0.87A 1xdkB-3dobA:
undetectable		 1xdkB-3dobA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 3dob HEAT SHOCK 70 KDA
PROTEIN F44E5.5
(Caenorhabditis
elegans) 		4 / 7 VAL A 443
ILE A 404
VAL A 489
ILE A 504
 None
 0.71A 5bmvC-3dobA:
undetectable		 5bmvC-3dobA:
16.12