SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3doj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AQB_A_RTLA185_0 (RETINOL-BINDING PROTEIN)	3doj	DEHYDROGENASE-LIKE PROTEIN (Arabidopsis thaliana)	5 / 10	ALA A 127 VAL A 173 MET A 63 LEU A 135 PHE A 231	None	1.34A	1aqbA-3dojA: undetectable	1aqbA-3dojA: 18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZZ_A_SAMA635_0 (ACLACINOMYCIN-10-HYD ROXYLASE)	3doj	DEHYDROGENASE-LIKE PROTEIN (Arabidopsis thaliana)	5 / 12	GLY A 110 GLY A 112 GLY A 113 LEU A 81 ASN A 105	None	1.20A	1qzzA-3dojA: 5.0	1qzzA-3dojA: 23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PLW_A_SAMA203_1 (RIBOSOMAL RNA METHYLTRANSFERASE, PUTATIVE)	3doj	DEHYDROGENASE-LIKE PROTEIN (Arabidopsis thaliana)	3 / 3	SER A 94 ASP A 97 ASP A 66	None	0.72A	2plwA-3dojA: 5.3	2plwA-3dojA: 21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B6R_B_CRNB603_1 (CREATINE KINASE B-TYPE)	3doj	DEHYDROGENASE-LIKE PROTEIN (Arabidopsis thaliana)	4 / 6	THR A 95 VAL A 96 LEU A 171 SER A 101	None	1.04A	3b6rB-3dojA: undetectable	3b6rB-3dojA: 23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3F8W_A_ADNA300_1 (PURINE-NUCLEOSIDE PHOSPHORYLASE)	3doj	DEHYDROGENASE-LIKE PROTEIN (Arabidopsis thaliana)	5 / 12	SER A 94 TYR A 90 GLY A 164 VAL A 163 VAL A 96	None	1.16A	3f8wA-3dojA: undetectable	3f8wA-3dojA: 22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XNX_A_41XA707_1 (TRANSPORTER)	3doj	DEHYDROGENASE-LIKE PROTEIN (Arabidopsis thaliana)	5 / 11	PHE A 184 ALA A 191 GLY A 219 SER A 185 GLY A 187	None	1.12A	4xnxA-3dojA: undetectable	4xnxA-3dojA: 20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5O96_A_SAMA501_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E)	3doj	DEHYDROGENASE-LIKE PROTEIN (Arabidopsis thaliana)	5 / 11	LEU A 153 GLY A 118 SER A 16 LEU A 19 ALA A 149	None	1.11A	5o96A-3dojA: 2.4 5o96B-3dojA: 3.2	5o96A-3dojA: 23.17 5o96B-3dojA: 23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6E5Z_A_CCSA106_0 (PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1)	3doj	DEHYDROGENASE-LIKE PROTEIN (Arabidopsis thaliana)	5 / 10	GLY A 166 GLY A 164 ALA A 167 THR A 95 GLY A 118	None	1.14A	6e5zA-3dojA: 5.5	6e5zA-3dojA: 25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H0F_H_Y70H502_0 (IKAROS (IKZF1) PROTEIN CEREBLON)	3doj	DEHYDROGENASE-LIKE PROTEIN (Arabidopsis thaliana)	5 / 12	ASN A 182 PHE A 215 GLN A 236 ASN A 261 GLY A 178	None	1.46A	6h0fH-3dojA: 0.0 6h0fI-3dojA: 0.0	6h0fH-3dojA: 16.16 6h0fI-3dojA: 8.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AQB_A_RTLA185_0","RETINOL-BINDING PROTEIN","3doj","DEHYDROGENASE-LIKE PROTEIN","Arabidopsis thaliana",5,"ALA A 127;VAL A 173;MET A  63;LEU A 135;PHE A 231","None","1.34A","1aqbA-3dojA:undetectable","1aqbA-3dojA:18.09"],["1QZZ_A_SAMA635_0","ACLACINOMYCIN-10-HYDROXYLASE","3doj","DEHYDROGENASE-LIKE PROTEIN","Arabidopsis thaliana",5,"GLY A 110;GLY A 112;GLY A 113;LEU A  81;ASN A 105","None","1.20A","1qzzA-3dojA:5.0","1qzzA-3dojA:23.38"],["2PLW_A_SAMA203_1","RIBOSOMAL RNA METHYLTRANSFERASE, PUTATIVE","3doj","DEHYDROGENASE-LIKE PROTEIN","Arabidopsis thaliana",3,"SER A  94;ASP A  97;ASP A  66","None","0.72A","2plwA-3dojA:5.3","2plwA-3dojA:21.02"],["3B6R_B_CRNB603_1","CREATINE KINASE B-TYPE","3doj","DEHYDROGENASE-LIKE PROTEIN","Arabidopsis thaliana",4,"THR A  95;VAL A  96;LEU A 171;SER A 101","None","1.04A","3b6rB-3dojA:undetectable","3b6rB-3dojA:23.32"],["3F8W_A_ADNA300_1","PURINE-NUCLEOSIDE PHOSPHORYLASE","3doj","DEHYDROGENASE-LIKE PROTEIN","Arabidopsis thaliana",5,"SER A  94;TYR A  90;GLY A 164;VAL A 163;VAL A  96","None","1.16A","3f8wA-3dojA:undetectable","3f8wA-3dojA:22.82"],["4XNX_A_41XA707_1","TRANSPORTER","3doj","DEHYDROGENASE-LIKE PROTEIN","Arabidopsis thaliana",5,"PHE A 184;ALA A 191;GLY A 219;SER A 185;GLY A 187","None","1.12A","4xnxA-3dojA:undetectable","4xnxA-3dojA:20.33"],["5O96_A_SAMA501_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E","3doj","DEHYDROGENASE-LIKE PROTEIN","Arabidopsis thaliana",5,"LEU A 153;GLY A 118;SER A  16;LEU A  19;ALA A 149","None","1.11A","5o96A-3dojA:2.4;5o96B-3dojA:3.2","5o96A-3dojA:23.17;5o96B-3dojA:23.17"],["6E5Z_A_CCSA106_0","PROTEIN\/NUCLEIC ACID DEGLYCASE DJ-1","3doj","DEHYDROGENASE-LIKE PROTEIN","Arabidopsis thaliana",5,"GLY A 166;GLY A 164;ALA A 167;THR A  95;GLY A 118","None","1.14A","6e5zA-3dojA:5.5","6e5zA-3dojA:25.66"],["6H0F_H_Y70H502_0","IKAROS (IKZF1);PROTEIN CEREBLON","3doj","DEHYDROGENASE-LIKE PROTEIN","Arabidopsis thaliana",5,"ASN A 182;PHE A 215;GLN A 236;ASN A 261;GLY A 178","None","1.46A","6h0fH-3dojA:0.0;6h0fI-3dojA:0.0","6h0fH-3dojA:16.16;6h0fI-3dojA:8.80"]]