SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dou'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DF7_A_MTXA501_2 (DIHYDROFOLATE REDUCTASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	3 / 3	TRP A 52 ARG A 81 THR A 53	SAM A 1 (-4.0A) None None	0.84A	1df7A-3douA: 2.3	1df7A-3douA: 19.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EIZ_A_SAMA301_0 (FTSJ)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	8 / 12	ALA A 22 GLY A 46 PRO A 49 GLY A 50 GLY A 51 TRP A 52 LEU A 68 LYS A 151	SAM A 1 (-3.3A) SAM A 1 (-3.5A) SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-4.2A) SAM A 1 (-3.5A)	0.33A	1eizA-3douA: 26.9	1eizA-3douA: 33.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EIZ_A_SAMA301_1 (FTSJ)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	3 / 3	ASP A 67 ASP A 83 ASP A 111	SAM A 1 (-2.7A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.15A	1eizA-3douA: 26.9	1eizA-3douA: 33.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EJ0_A_SAMA301_0 (FTSJ)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	8 / 12	ALA A 22 GLY A 46 PRO A 49 GLY A 50 GLY A 51 TRP A 52 LEU A 68 LYS A 151	SAM A 1 (-3.3A) SAM A 1 (-3.5A) SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-4.2A) SAM A 1 (-3.5A)	0.33A	1ej0A-3douA: 26.8	1ej0A-3douA: 33.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EJ0_A_SAMA301_1 (FTSJ)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	3 / 3	ASP A 67 ASP A 83 ASP A 111	SAM A 1 (-2.7A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.20A	1ej0A-3douA: 26.8	1ej0A-3douA: 33.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_A_IBPA701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 9	VAL A 36 LEU A 26 ILE A 63 ALA A 60 LEU A 59	None	1.20A	1eqgA-3douA: undetectable	1eqgA-3douA: 15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P7L_C_SAMC685_1 (S-ADENOSYLMETHIONINE SYNTHETASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	4 / 8	ALA A 96 ASP A 67 ILE A 66 ILE A 84	None SAM A 1 (-2.7A) None SAM A 1 (-3.9A)	0.89A	1p7lD-3douA: undetectable	1p7lD-3douA: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P7L_C_SAMC885_0 (S-ADENOSYLMETHIONINE SYNTHETASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	4 / 8	ALA A 96 ASP A 67 ILE A 66 ILE A 84	None SAM A 1 (-2.7A) None SAM A 1 (-3.9A)	0.91A	1p7lC-3douA: undetectable	1p7lC-3douA: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG9_A_SAMA385_1 (S-ADENOSYLMETHIONINE SYNTHETASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	4 / 8	ALA A 96 ASP A 67 ILE A 66 ILE A 84	None SAM A 1 (-2.7A) None SAM A 1 (-3.9A)	0.87A	1rg9B-3douA: undetectable	1rg9B-3douA: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG9_B_SAMB485_0 (S-ADENOSYLMETHIONINE SYNTHETASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	4 / 8	ALA A 96 ASP A 67 ILE A 66 ILE A 84	None SAM A 1 (-2.7A) None SAM A 1 (-3.9A)	0.89A	1rg9A-3douA: undetectable	1rg9A-3douA: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG9_C_SAMC585_1 (S-ADENOSYLMETHIONINE SYNTHETASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	4 / 8	ALA A 96 ASP A 67 ILE A 66 ILE A 84	None SAM A 1 (-2.7A) None SAM A 1 (-3.9A)	0.88A	1rg9D-3douA: undetectable	1rg9D-3douA: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG9_C_SAMC685_0 (S-ADENOSYLMETHIONINE SYNTHETASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	4 / 8	ALA A 96 ASP A 67 ILE A 66 ILE A 84	None SAM A 1 (-2.7A) None SAM A 1 (-3.9A)	0.90A	1rg9C-3douA: undetectable	1rg9C-3douA: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SQF_A_SAMA430_1 (SUN PROTEIN)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	3 / 3	PRO A 49 ASP A 67 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-2.7A) SAM A 1 (-3.7A)	0.35A	1sqfA-3douA: 7.2	1sqfA-3douA: 17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	4 / 7	TYR A 128 MET A 157 ASP A 160 LYS A 167	None	1.46A	1t03A-3douA: undetectable	1t03A-3douA: 14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NYU_A_SAMA201_0 (PUTATIVE RIBOSOMAL RNA METHYLTRANSFERASE 2)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 50 TRP A 52 LEU A 68 LYS A 151	SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-4.0A) SAM A 1 (-4.2A) SAM A 1 (-3.5A)	0.26A	2nyuA-3douA: 24.8	2nyuA-3douA: 26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NYU_A_SAMA201_1 (PUTATIVE RIBOSOMAL RNA METHYLTRANSFERASE 2)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	4 / 4	PRO A 49 ASP A 67 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-2.7A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.50A	2nyuA-3douA: 24.8	2nyuA-3douA: 26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NYU_B_SAMB201_0 (PUTATIVE RIBOSOMAL RNA METHYLTRANSFERASE 2)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 50 TRP A 52 LEU A 68 LYS A 151	SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-4.0A) SAM A 1 (-4.2A) SAM A 1 (-3.5A)	0.29A	2nyuB-3douA: 25.3	2nyuB-3douA: 26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NYU_B_SAMB201_1 (PUTATIVE RIBOSOMAL RNA METHYLTRANSFERASE 2)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	4 / 5	PRO A 49 ASP A 67 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-2.7A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.47A	2nyuB-3douA: 25.3	2nyuB-3douA: 26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_A_SAMA300_0 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 LEU A 68 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-4.2A) SAM A 1 (-3.7A)	0.49A	2oxtA-3douA: 14.5	2oxtA-3douA: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_B_SAMB300_0 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 50 TRP A 52 LEU A 68 LYS A 151	SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-4.0A) SAM A 1 (-4.2A) SAM A 1 (-3.5A)	0.57A	2oxtB-3douA: 14.6	2oxtB-3douA: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_C_SAMC300_0 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	6 / 12	GLY A 46 GLY A 51 TRP A 52 LEU A 68 ASP A 111 LYS A 151	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-4.2A) SAM A 1 (-3.7A) SAM A 1 (-3.5A)	0.56A	2oxtC-3douA: 14.5	2oxtC-3douA: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_C_SAMC300_0 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	TRP A 52 LEU A 68 ILE A 84 ASP A 111 LYS A 151	SAM A 1 (-4.0A) SAM A 1 (-4.2A) SAM A 1 (-3.9A) SAM A 1 (-3.7A) SAM A 1 (-3.5A)	0.85A	2oxtC-3douA: 14.5	2oxtC-3douA: 18.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2PLW_A_SAMA203_0 (RIBOSOMAL RNA METHYLTRANSFERASE, PUTATIVE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	6 / 12	ALA A 22 GLY A 46 PRO A 49 GLY A 50 TRP A 52 ALA A 112	SAM A 1 (-3.3A) SAM A 1 (-3.5A) SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-4.0A) SAM A 1 (-3.7A)	0.27A	2plwA-3douA: 25.4	2plwA-3douA: 31.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2PLW_A_SAMA203_0 (RIBOSOMAL RNA METHYLTRANSFERASE, PUTATIVE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	6 / 12	ALA A 22 GLY A 46 PRO A 49 GLY A 50 TRP A 52 ILE A 84	SAM A 1 (-3.3A) SAM A 1 (-3.5A) SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-4.0A) SAM A 1 (-3.9A)	0.66A	2plwA-3douA: 25.4	2plwA-3douA: 31.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PXC_A_SAMA500_0 (GENOME POLYPROTEIN [CONTAINS: CAPSID PROTEIN C (CORE PROTEIN) ENVELOPE PROTEIN M (MATRIX PROTEIN) MAJOR ENVELOPE PROTEIN E NON-STRUCTURAL PROTEIN 1 (NS1) NON-STRUCTURAL PROTEIN 2A (NS2A) FLAVIVIRIN PROTEASE NS2B REGULATORY SUBUNIT FLAVIVIRIN PROTEASE NS3 CATALYTIC SUBUNIT NON-STRUCTURAL PROTEIN 4A (NS4A) NON-STRUCTURAL PROTEIN 4B (NS4B) RNA-DIRECTED RNA POLYMERASE (EC 2.7.7.48) (NS5)])	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.50A	2pxcA-3douA: 14.2	2pxcA-3douA: 22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DOU_A_SAMA1_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	11 / 12	ALA A 22 GLY A 46 SER A 48 PRO A 49 GLY A 50 GLY A 51 TRP A 52 LEU A 68 ILE A 84 ALA A 112 LYS A 151	SAM A 1 (-3.3A) SAM A 1 (-3.5A) SAM A 1 (-4.5A) SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-4.2A) SAM A 1 (-3.9A) SAM A 1 (-3.7A) SAM A 1 (-3.5A)	0.46A	3douA-3douA: 37.9	3douA-3douA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DOU_A_SAMA1_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	7 / 12	ALA A 22 SER A 47 GLY A 50 GLY A 51 LEU A 68 ILE A 84 ALA A 112	SAM A 1 (-3.3A) None SAM A 1 (-3.8A) SAM A 1 (-3.2A) SAM A 1 (-4.2A) SAM A 1 (-3.9A) SAM A 1 (-3.7A)	1.29A	3douA-3douA: 37.9	3douA-3douA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DOU_A_SAMA1_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 50 ILE A 84 ALA A 112 LYS A 151	SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-3.9A) SAM A 1 (-3.7A) SAM A 1 (-3.5A)	0.94A	3douA-3douA: 37.9	3douA-3douA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DOU_A_SAMA1_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	6 / 12	GLY A 46 SER A 48 LEU A 68 GLN A 69 ILE A 84 ALA A 112	SAM A 1 (-3.5A) SAM A 1 (-4.5A) SAM A 1 (-4.2A) None SAM A 1 (-3.9A) SAM A 1 (-3.7A)	1.16A	3douA-3douA: 37.9	3douA-3douA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DOU_A_SAMA1_1 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	3 / 3	ASP A 67 ASP A 83 ASP A 111	SAM A 1 (-2.7A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.00A	3douA-3douA: 37.9	3douA-3douA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELU_A_SAMA4633_0 (METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 LEU A 68 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-4.2A) SAM A 1 (-3.7A)	0.33A	3eluA-3douA: 14.0	3eluA-3douA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELW_A_SAMA4633_0 (METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 LEU A 68 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-4.2A) SAM A 1 (-3.7A)	0.35A	3elwA-3douA: 14.5	3elwA-3douA: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EMB_A_SAMA4633_0 (METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 LEU A 68 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-4.2A) SAM A 1 (-3.7A)	0.33A	3embA-3douA: 14.6	3embA-3douA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GCZ_A_SAMA4633_0 (POLYPROTEIN)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	6 / 12	GLY A 46 GLY A 51 TRP A 52 LEU A 68 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-4.2A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.61A	3gczA-3douA: 14.7	3gczA-3douA: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IHT_A_SAMA200_0 (S-ADENOSYL-L-METHION INE METHYL TRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 50 ASP A 83 ILE A 84 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-3.6A) SAM A 1 (-3.9A) SAM A 1 (-3.7A)	0.56A	3ihtA-3douA: 11.7	3ihtA-3douA: 22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P97_A_SAMA263_0 (NON-STRUCTURAL PROTEIN 5)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.50A	3p97A-3douA: 13.8	3p97A-3douA: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P97_C_SAMC263_0 (NON-STRUCTURAL PROTEIN 5)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.48A	3p97C-3douA: 13.7	3p97C-3douA: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFN_A_ROCA401_1 (HIV-1 PROTEASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 11	GLY A 39 ALA A 60 ASN A 57 VAL A 77 ILE A 102	None	0.82A	3ufnA-3douA: undetectable	3ufnA-3douA: 23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B17_A_SAMA1358_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	7 / 12	GLY A 46 PRO A 49 GLY A 50 GLY A 51 TRP A 52 ASP A 67 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-2.7A) SAM A 1 (-3.7A)	0.38A	4b17A-3douA: 15.1	4b17A-3douA: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B17_A_SAMA1358_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	6 / 12	PRO A 49 GLY A 50 TRP A 52 ASP A 67 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-4.0A) SAM A 1 (-2.7A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.79A	4b17A-3douA: 15.1	4b17A-3douA: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B17_A_SAMA1358_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	SER A 20 GLY A 46 GLY A 51 TRP A 52 ASP A 111	SAM A 1 ( 4.5A) SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.7A)	1.08A	4b17A-3douA: 15.1	4b17A-3douA: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTJ_A_SAMA1263_0 (NON-STRUCTURAL PROTEIN 5)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.46A	4ctjA-3douA: 13.7	4ctjA-3douA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTK_A_SAMA1263_0 (POLYPROTEIN)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.48A	4ctkA-3douA: 13.8	4ctkA-3douA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTK_C_SAMC1263_0 (POLYPROTEIN)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	SER A 20 GLY A 46 GLY A 51 TRP A 52 ASP A 111	SAM A 1 ( 4.5A) SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.7A)	0.81A	4ctkC-3douA: 13.7	4ctkC-3douA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EQ4_B_SALB601_1 (4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	4 / 8	LEU A 68 ILE A 130 VAL A 134 GLY A 46	SAM A 1 (-4.2A) None None SAM A 1 (-3.5A)	0.91A	4eq4B-3douA: undetectable	4eq4B-3douA: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_A_SAMA401_0 (METHYLTRANSFERASE NSUN4)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	PRO A 49 GLY A 50 GLY A 51 LEU A 68 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-3.2A) SAM A 1 (-4.2A) SAM A 1 (-3.7A)	0.58A	4fp9A-3douA: 8.8	4fp9A-3douA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_C_SAMC401_0 (METHYLTRANSFERASE NSUN4)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	PRO A 49 GLY A 50 GLY A 51 LEU A 68 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-3.2A) SAM A 1 (-4.2A) SAM A 1 (-3.7A)	0.58A	4fp9C-3douA: 7.9	4fp9C-3douA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_D_SAMD401_0 (METHYLTRANSFERASE NSUN4)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	PRO A 49 GLY A 50 GLY A 51 LEU A 68 ASP A 83	SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-3.2A) SAM A 1 (-4.2A) SAM A 1 (-3.6A)	0.64A	4fp9D-3douA: 9.1	4fp9D-3douA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_F_SAMF401_0 (METHYLTRANSFERASE NSUN4)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	PRO A 49 GLY A 50 GLY A 51 LEU A 68 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-3.2A) SAM A 1 (-4.2A) SAM A 1 (-3.7A)	0.57A	4fp9F-3douA: 9.0	4fp9F-3douA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FZV_A_SAMA401_0 (PUTATIVE METHYLTRANSFERASE NSUN4)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	PRO A 49 GLY A 50 GLY A 51 LEU A 68 ASP A 83	SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-3.2A) SAM A 1 (-4.2A) SAM A 1 (-3.6A)	0.66A	4fzvA-3douA: 8.9	4fzvA-3douA: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N48_A_SAMA601_1 (CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-M ETHYLTRANSFERASE 1)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	4 / 5	ALA A 22 GLY A 51 ASP A 83 ASP A 111	SAM A 1 (-3.3A) SAM A 1 (-3.2A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.36A	4n48A-3douA: 16.4	4n48A-3douA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N48_B_SAMB601_1 (CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-M ETHYLTRANSFERASE 1)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	4 / 5	PRO A 49 GLY A 51 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.35A	4n48B-3douA: 16.3	4n48B-3douA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N49_A_SAMA601_0 (CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-M ETHYLTRANSFERASE 1)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	ALA A 22 PRO A 49 GLY A 50 LEU A 68 ILE A 84	SAM A 1 (-3.3A) SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-4.2A) SAM A 1 (-3.9A)	0.63A	4n49A-3douA: 16.0	4n49A-3douA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OK1_A_198A1001_1 (ANDROGEN RECEPTOR)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 MET A 71 THR A 53 ILE A 63 VAL A 77	SAM A 1 (-3.5A) None None None None	1.15A	4ok1A-3douA: undetectable	4ok1A-3douA: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OKW_A_198A1001_1 (ANDROGEN RECEPTOR)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 MET A 71 THR A 53 ILE A 63 VAL A 77	SAM A 1 (-3.5A) None None None None	1.17A	4okwA-3douA: undetectable	4okwA-3douA: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PGH_A_SAMA401_0 (CAFFEIC ACID O-METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 11	SER A 20 GLY A 46 ASP A 67 LEU A 68 ASP A 83	SAM A 1 ( 4.5A) SAM A 1 (-3.5A) SAM A 1 (-2.7A) SAM A 1 (-4.2A) SAM A 1 (-3.6A)	1.11A	4pghA-3douA: 11.0	4pghA-3douA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PGH_B_SAMB401_0 (CAFFEIC ACID O-METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	SER A 20 GLY A 46 ASP A 67 LEU A 68 ASP A 83	SAM A 1 ( 4.5A) SAM A 1 (-3.5A) SAM A 1 (-2.7A) SAM A 1 (-4.2A) SAM A 1 (-3.6A)	1.24A	4pghB-3douA: 10.9	4pghB-3douA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PGH_C_SAMC401_0 (CAFFEIC ACID O-METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 11	SER A 20 GLY A 46 ASP A 67 LEU A 68 ASP A 83	SAM A 1 ( 4.5A) SAM A 1 (-3.5A) SAM A 1 (-2.7A) SAM A 1 (-4.2A) SAM A 1 (-3.6A)	1.12A	4pghC-3douA: 11.7	4pghC-3douA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCI_A_SAMA2409_0 (RNA-DIRECTED RNA POLYMERASE L)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 50 LEU A 68 ALA A 112 LYS A 151	SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-4.2A) SAM A 1 (-3.7A) SAM A 1 (-3.5A)	0.58A	4uciA-3douA: 8.8	4uciA-3douA: 20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCI_B_SAMB2409_0 (RNA-DIRECTED RNA POLYMERASE L)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 50 LEU A 68 ALA A 112 LYS A 151	SAM A 1 (-3.5A) SAM A 1 (-3.8A) SAM A 1 (-4.2A) SAM A 1 (-3.7A) SAM A 1 (-3.5A)	0.59A	4uciB-3douA: 8.7	4uciB-3douA: 20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E9Q_A_SAMA301_0 (GENOME POLYPROTEIN)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.47A	5e9qA-3douA: 13.7	5e9qA-3douA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E9Q_C_SAMC4000_0 (GENOME POLYPROTEIN)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.50A	5e9qC-3douA: 13.7	5e9qC-3douA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EC8_A_SAMA301_0 (GENOME POLYPROTEIN)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	SER A 20 GLY A 46 GLY A 51 TRP A 52 ASP A 111	SAM A 1 ( 4.5A) SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.7A)	0.75A	5ec8A-3douA: 13.8	5ec8A-3douA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EC8_C_SAMC4000_0 (GENOME POLYPROTEIN)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.42A	5ec8C-3douA: 13.6	5ec8C-3douA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EHG_A_SAMA301_0 (RNA-DIRECTED RNA POLYMERASE NS5)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.47A	5ehgA-3douA: 13.8	5ehgA-3douA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EHI_A_SAMA4001_0 (NS5 METHYLTRANSFERASE DENGUE VIRUS)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.49A	5ehiA-3douA: 13.7	5ehiA-3douA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EHI_C_SAMC4000_0 (NS5 METHYLTRANSFERASE DENGUE VIRUS)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.45A	5ehiC-3douA: 13.9	5ehiC-3douA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EIF_A_SAMA301_0 (GENOME POLYPROTEIN)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.48A	5eifA-3douA: 13.7	5eifA-3douA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EIF_C_SAMC4000_0 (GENOME POLYPROTEIN)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.45A	5eifC-3douA: 13.8	5eifC-3douA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EIW_A_SAMA301_0 (NS5 METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.50A	5eiwA-3douA: 13.8	5eiwA-3douA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EIW_C_SAMC4000_0 (NS5 METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.48A	5eiwC-3douA: 13.6	5eiwC-3douA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EKX_A_SAMA301_0 (NS5 METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.46A	5ekxA-3douA: 13.8	5ekxA-3douA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKM_A_SAMA311_0 (NS5 METHYL TRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.48A	5ikmA-3douA: 13.9	5ikmA-3douA: 17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J4N_B_AG2B501_1 (ARGININE/AGMATINE ANTIPORTER)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	4 / 6	ILE A 64 GLY A 50 MET A 71 ILE A 63	None SAM A 1 (-3.8A) None None	0.82A	5j4nB-3douA: undetectable	5j4nB-3douA: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KQS_A_SAMA307_0 (GENOME POLYPROTEIN)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.37A	5kqsA-3douA: 14.0	5kqsA-3douA: 19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NJV_A_SAMA301_0 (NS5)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.45A	5njvA-3douA: 13.9	5njvA-3douA: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NJV_B_SAMB301_0 (NS5)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.44A	5njvB-3douA: 13.9	5njvB-3douA: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WWS_A_SAMA501_0 (PUTATIVE METHYLTRANSFERASE NSUN6)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	PRO A 49 GLY A 51 ASP A 67 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-2.7A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.64A	5wwsA-3douA: 10.0	5wwsA-3douA: 18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WWS_B_SAMB501_0 (PUTATIVE METHYLTRANSFERASE NSUN6)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	PRO A 49 GLY A 51 ASP A 67 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-2.7A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.66A	5wwsB-3douA: 9.8	5wwsB-3douA: 18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_A_SAMA601_0 (NS5 METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.50A	5wz1A-3douA: 13.8	5wz1A-3douA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_C_SAMC601_0 (NS5 METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.51A	5wz1C-3douA: 13.8	5wz1C-3douA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_D_SAMD601_0 (NS5 METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.56A	5wz1D-3douA: 13.9	5wz1D-3douA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_E_SAME601_0 (NS5 METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.48A	5wz1E-3douA: 13.8	5wz1E-3douA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_F_SAMF601_0 (NS5 METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.57A	5wz1F-3douA: 13.9	5wz1F-3douA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_G_SAMG601_0 (NS5 METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.52A	5wz1G-3douA: 13.8	5wz1G-3douA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_H_SAMH601_0 (NS5 METHYLTRANSFERASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.52A	5wz1H-3douA: 13.8	5wz1H-3douA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ2_A_SAMA601_0 (NS5 MTASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.41A	5wz2A-3douA: 13.8	5wz2A-3douA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ2_B_SAMB601_0 (NS5 MTASE)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 TRP A 52 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.0A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.44A	5wz2B-3douA: 13.9	5wz2B-3douA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YN6_A_SAMA401_0 (NSP16 PROTEIN)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	5 / 12	GLY A 46 GLY A 51 LEU A 68 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-4.2A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.97A	5yn6A-3douA: 7.6	5yn6A-3douA: 20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YNI_A_SAMA401_0 (NSP16 PROTEIN)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	6 / 12	GLY A 46 GLY A 51 ASP A 67 LEU A 68 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-2.7A) SAM A 1 (-4.2A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	1.01A	5yniA-3douA: 12.9	5yniA-3douA: 20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YNM_A_SAMA401_0 (NSP16 PROTEIN)	3dou	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J (Thermoplasma volcanium)	6 / 12	GLY A 46 GLY A 51 ASP A 67 LEU A 68 ASP A 83 ASP A 111	SAM A 1 (-3.5A) SAM A 1 (-3.2A) SAM A 1 (-2.7A) SAM A 1 (-4.2A) SAM A 1 (-3.6A) SAM A 1 (-3.7A)	0.98A	5ynmA-3douA: 13.0	5ynmA-3douA: 20.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DF7_A_MTXA501_2","DIHYDROFOLATE REDUCTASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",3,"TRP A  52;ARG A  81;THR A  53","SAM A   1 (-4.0A);None;None","0.84A","1df7A-3douA:2.3","1df7A-3douA:19.70"],["1EIZ_A_SAMA301_0","FTSJ","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",8,"ALA A  22;GLY A  46;PRO A  49;GLY A  50;GLY A  51;TRP A  52;LEU A  68;LYS A 151","SAM A   1 (-3.3A);SAM A   1 (-3.5A);SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-4.2A);SAM A   1 (-3.5A)","0.33A","1eizA-3douA:26.9","1eizA-3douA:33.69"],["1EIZ_A_SAMA301_1","FTSJ","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",3,"ASP A  67;ASP A  83;ASP A 111","SAM A   1 (-2.7A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.15A","1eizA-3douA:26.9","1eizA-3douA:33.69"],["1EJ0_A_SAMA301_0","FTSJ","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",8,"ALA A  22;GLY A  46;PRO A  49;GLY A  50;GLY A  51;TRP A  52;LEU A  68;LYS A 151","SAM A   1 (-3.3A);SAM A   1 (-3.5A);SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-4.2A);SAM A   1 (-3.5A)","0.33A","1ej0A-3douA:26.8","1ej0A-3douA:33.69"],["1EJ0_A_SAMA301_1","FTSJ","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",3,"ASP A  67;ASP A  83;ASP A 111","SAM A   1 (-2.7A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.20A","1ej0A-3douA:26.8","1ej0A-3douA:33.69"],["1EQG_A_IBPA701_1","PROSTAGLANDIN H2 SYNTHASE-1","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"VAL A  36;LEU A  26;ILE A  63;ALA A  60;LEU A  59","None","1.20A","1eqgA-3douA:undetectable","1eqgA-3douA:15.40"],["1P7L_C_SAMC685_1","S-ADENOSYLMETHIONINE SYNTHETASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",4,"ALA A  96;ASP A  67;ILE A  66;ILE A  84","None;SAM A   1 (-2.7A);None;SAM A   1 (-3.9A)","0.89A","1p7lD-3douA:undetectable","1p7lD-3douA:18.80"],["1P7L_C_SAMC885_0","S-ADENOSYLMETHIONINE SYNTHETASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",4,"ALA A  96;ASP A  67;ILE A  66;ILE A  84","None;SAM A   1 (-2.7A);None;SAM A   1 (-3.9A)","0.91A","1p7lC-3douA:undetectable","1p7lC-3douA:18.80"],["1RG9_A_SAMA385_1","S-ADENOSYLMETHIONINE SYNTHETASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",4,"ALA A  96;ASP A  67;ILE A  66;ILE A  84","None;SAM A   1 (-2.7A);None;SAM A   1 (-3.9A)","0.87A","1rg9B-3douA:undetectable","1rg9B-3douA:18.80"],["1RG9_B_SAMB485_0","S-ADENOSYLMETHIONINE SYNTHETASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",4,"ALA A  96;ASP A  67;ILE A  66;ILE A  84","None;SAM A   1 (-2.7A);None;SAM A   1 (-3.9A)","0.89A","1rg9A-3douA:undetectable","1rg9A-3douA:18.80"],["1RG9_C_SAMC585_1","S-ADENOSYLMETHIONINE SYNTHETASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",4,"ALA A  96;ASP A  67;ILE A  66;ILE A  84","None;SAM A   1 (-2.7A);None;SAM A   1 (-3.9A)","0.88A","1rg9D-3douA:undetectable","1rg9D-3douA:18.80"],["1RG9_C_SAMC685_0","S-ADENOSYLMETHIONINE SYNTHETASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",4,"ALA A  96;ASP A  67;ILE A  66;ILE A  84","None;SAM A   1 (-2.7A);None;SAM A   1 (-3.9A)","0.90A","1rg9C-3douA:undetectable","1rg9C-3douA:18.80"],["1SQF_A_SAMA430_1","SUN PROTEIN","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",3,"PRO A  49;ASP A  67;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-2.7A);SAM A   1 (-3.7A)","0.35A","1sqfA-3douA:7.2","1sqfA-3douA:17.17"],["1T03_P_TFOP822_1","POL POLYPROTEIN;SYNTHETIC OLIGONUCLEOTIDE PRIMER","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",4,"TYR A 128;MET A 157;ASP A 160;LYS A 167","None","1.46A","1t03A-3douA:undetectable","1t03A-3douA:14.31"],["2NYU_A_SAMA201_0","PUTATIVE RIBOSOMAL RNA METHYLTRANSFERASE 2","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  50;TRP A  52;LEU A  68;LYS A 151","SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-4.0A);SAM A   1 (-4.2A);SAM A   1 (-3.5A)","0.26A","2nyuA-3douA:24.8","2nyuA-3douA:26.87"],["2NYU_A_SAMA201_1","PUTATIVE RIBOSOMAL RNA METHYLTRANSFERASE 2","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",4,"PRO A  49;ASP A  67;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-2.7A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.50A","2nyuA-3douA:24.8","2nyuA-3douA:26.87"],["2NYU_B_SAMB201_0","PUTATIVE RIBOSOMAL RNA METHYLTRANSFERASE 2","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  50;TRP A  52;LEU A  68;LYS A 151","SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-4.0A);SAM A   1 (-4.2A);SAM A   1 (-3.5A)","0.29A","2nyuB-3douA:25.3","2nyuB-3douA:26.87"],["2NYU_B_SAMB201_1","PUTATIVE RIBOSOMAL RNA METHYLTRANSFERASE 2","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",4,"PRO A  49;ASP A  67;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-2.7A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.47A","2nyuB-3douA:25.3","2nyuB-3douA:26.87"],["2OXT_A_SAMA300_0","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;LEU A  68;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-4.2A);SAM A   1 (-3.7A)","0.49A","2oxtA-3douA:14.5","2oxtA-3douA:18.15"],["2OXT_B_SAMB300_0","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  50;TRP A  52;LEU A  68;LYS A 151","SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-4.0A);SAM A   1 (-4.2A);SAM A   1 (-3.5A)","0.57A","2oxtB-3douA:14.6","2oxtB-3douA:18.15"],["2OXT_C_SAMC300_0","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",6,"GLY A  46;GLY A  51;TRP A  52;LEU A  68;ASP A 111;LYS A 151","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-4.2A);SAM A   1 (-3.7A);SAM A   1 (-3.5A)","0.56A","2oxtC-3douA:14.5","2oxtC-3douA:18.15"],["2OXT_C_SAMC300_0","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"TRP A  52;LEU A  68;ILE A  84;ASP A 111;LYS A 151","SAM A   1 (-4.0A);SAM A   1 (-4.2A);SAM A   1 (-3.9A);SAM A   1 (-3.7A);SAM A   1 (-3.5A)","0.85A","2oxtC-3douA:14.5","2oxtC-3douA:18.15"],["2PLW_A_SAMA203_0","RIBOSOMAL RNA METHYLTRANSFERASE, PUTATIVE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",6,"ALA A  22;GLY A  46;PRO A  49;GLY A  50;TRP A  52;ALA A 112","SAM A   1 (-3.3A);SAM A   1 (-3.5A);SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-4.0A);SAM A   1 (-3.7A)","0.27A","2plwA-3douA:25.4","2plwA-3douA:31.55"],["2PLW_A_SAMA203_0","RIBOSOMAL RNA METHYLTRANSFERASE, PUTATIVE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",6,"ALA A  22;GLY A  46;PRO A  49;GLY A  50;TRP A  52;ILE A  84","SAM A   1 (-3.3A);SAM A   1 (-3.5A);SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-4.0A);SAM A   1 (-3.9A)","0.66A","2plwA-3douA:25.4","2plwA-3douA:31.55"],["2PXC_A_SAMA500_0","GENOME POLYPROTEIN [CONTAINS: CAPSID PROTEIN C (CORE PROTEIN); ENVELOPE PROTEIN M (MATRIX PROTEIN); MAJOR ENVELOPE PROTEIN E; NON-STRUCTURAL PROTEIN 1 (NS1); NON-STRUCTURAL PROTEIN 2A (NS2A); FLAVIVIRIN PROTEASE NS2B REGULATORY SUBUNIT; FLAVIVIRIN PROTEASE NS3 CATALYTIC SUBUNIT; NON-STRUCTURAL PROTEIN 4A (NS4A); NON-STRUCTURAL PROTEIN 4B (NS4B); RNA-DIRECTED RNA POLYMERASE (EC 2.7.7.48) (NS5)]","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.50A","2pxcA-3douA:14.2","2pxcA-3douA:22.18"],["3DOU_A_SAMA1_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",11,"ALA A  22;GLY A  46;SER A  48;PRO A  49;GLY A  50;GLY A  51;TRP A  52;LEU A  68;ILE A  84;ALA A 112;LYS A 151","SAM A   1 (-3.3A);SAM A   1 (-3.5A);SAM A   1 (-4.5A);SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-4.2A);SAM A   1 (-3.9A);SAM A   1 (-3.7A);SAM A   1 (-3.5A)","0.46A","3douA-3douA:37.9","3douA-3douA:100.00"],["3DOU_A_SAMA1_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",7,"ALA A  22;SER A  47;GLY A  50;GLY A  51;LEU A  68;ILE A  84;ALA A 112","SAM A   1 (-3.3A);None;SAM A   1 (-3.8A);SAM A   1 (-3.2A);SAM A   1 (-4.2A);SAM A   1 (-3.9A);SAM A   1 (-3.7A)","1.29A","3douA-3douA:37.9","3douA-3douA:100.00"],["3DOU_A_SAMA1_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  50;ILE A  84;ALA A 112;LYS A 151","SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-3.9A);SAM A   1 (-3.7A);SAM A   1 (-3.5A)","0.94A","3douA-3douA:37.9","3douA-3douA:100.00"],["3DOU_A_SAMA1_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",6,"GLY A  46;SER A  48;LEU A  68;GLN A  69;ILE A  84;ALA A 112","SAM A   1 (-3.5A);SAM A   1 (-4.5A);SAM A   1 (-4.2A);None;SAM A   1 (-3.9A);SAM A   1 (-3.7A)","1.16A","3douA-3douA:37.9","3douA-3douA:100.00"],["3DOU_A_SAMA1_1","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",3,"ASP A  67;ASP A  83;ASP A 111","SAM A   1 (-2.7A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.00A","3douA-3douA:37.9","3douA-3douA:100.00"],["3ELU_A_SAMA4633_0","METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;LEU A  68;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-4.2A);SAM A   1 (-3.7A)","0.33A","3eluA-3douA:14.0","3eluA-3douA:undetectable"],["3ELW_A_SAMA4633_0","METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;LEU A  68;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-4.2A);SAM A   1 (-3.7A)","0.35A","3elwA-3douA:14.5","3elwA-3douA:21.12"],["3EMB_A_SAMA4633_0","METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;LEU A  68;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-4.2A);SAM A   1 (-3.7A)","0.33A","3embA-3douA:14.6","3embA-3douA:undetectable"],["3GCZ_A_SAMA4633_0","POLYPROTEIN","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",6,"GLY A  46;GLY A  51;TRP A  52;LEU A  68;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-4.2A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.61A","3gczA-3douA:14.7","3gczA-3douA:19.37"],["3IHT_A_SAMA200_0","S-ADENOSYL-L-METHIONINE METHYL TRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  50;ASP A  83;ILE A  84;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-3.6A);SAM A   1 (-3.9A);SAM A   1 (-3.7A)","0.56A","3ihtA-3douA:11.7","3ihtA-3douA:22.16"],["3P97_A_SAMA263_0","NON-STRUCTURAL PROTEIN 5","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.50A","3p97A-3douA:13.8","3p97A-3douA:19.56"],["3P97_C_SAMC263_0","NON-STRUCTURAL PROTEIN 5","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.48A","3p97C-3douA:13.7","3p97C-3douA:19.56"],["3UFN_A_ROCA401_1","HIV-1 PROTEASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  39;ALA A  60;ASN A  57;VAL A  77;ILE A 102","None","0.82A","3ufnA-3douA:undetectable","3ufnA-3douA:23.75"],["4B17_A_SAMA1358_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",7,"GLY A  46;PRO A  49;GLY A  50;GLY A  51;TRP A  52;ASP A  67;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-2.7A);SAM A   1 (-3.7A)","0.38A","4b17A-3douA:15.1","4b17A-3douA:21.22"],["4B17_A_SAMA1358_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",6,"PRO A  49;GLY A  50;TRP A  52;ASP A  67;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-4.0A);SAM A   1 (-2.7A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.79A","4b17A-3douA:15.1","4b17A-3douA:21.22"],["4B17_A_SAMA1358_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"SER A  20;GLY A  46;GLY A  51;TRP A  52;ASP A 111","SAM A   1 ( 4.5A);SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.7A)","1.08A","4b17A-3douA:15.1","4b17A-3douA:21.22"],["4CTJ_A_SAMA1263_0","NON-STRUCTURAL PROTEIN 5","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.46A","4ctjA-3douA:13.7","4ctjA-3douA:19.13"],["4CTK_A_SAMA1263_0","POLYPROTEIN","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.48A","4ctkA-3douA:13.8","4ctkA-3douA:19.13"],["4CTK_C_SAMC1263_0","POLYPROTEIN","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"SER A  20;GLY A  46;GLY A  51;TRP A  52;ASP A 111","SAM A   1 ( 4.5A);SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.7A)","0.81A","4ctkC-3douA:13.7","4ctkC-3douA:19.13"],["4EQ4_B_SALB601_1","4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",4,"LEU A  68;ILE A 130;VAL A 134;GLY A  46","SAM A   1 (-4.2A);None;None;SAM A   1 (-3.5A)","0.91A","4eq4B-3douA:undetectable","4eq4B-3douA:16.26"],["4FP9_A_SAMA401_0","METHYLTRANSFERASE NSUN4","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"PRO A  49;GLY A  50;GLY A  51;LEU A  68;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-3.2A);SAM A   1 (-4.2A);SAM A   1 (-3.7A)","0.58A","4fp9A-3douA:8.8","4fp9A-3douA:18.26"],["4FP9_C_SAMC401_0","METHYLTRANSFERASE NSUN4","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"PRO A  49;GLY A  50;GLY A  51;LEU A  68;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-3.2A);SAM A   1 (-4.2A);SAM A   1 (-3.7A)","0.58A","4fp9C-3douA:7.9","4fp9C-3douA:18.26"],["4FP9_D_SAMD401_0","METHYLTRANSFERASE NSUN4","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"PRO A  49;GLY A  50;GLY A  51;LEU A  68;ASP A  83","SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-3.2A);SAM A   1 (-4.2A);SAM A   1 (-3.6A)","0.64A","4fp9D-3douA:9.1","4fp9D-3douA:18.26"],["4FP9_F_SAMF401_0","METHYLTRANSFERASE NSUN4","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"PRO A  49;GLY A  50;GLY A  51;LEU A  68;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-3.2A);SAM A   1 (-4.2A);SAM A   1 (-3.7A)","0.57A","4fp9F-3douA:9.0","4fp9F-3douA:18.26"],["4FZV_A_SAMA401_0","PUTATIVE METHYLTRANSFERASE NSUN4","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"PRO A  49;GLY A  50;GLY A  51;LEU A  68;ASP A  83","SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-3.2A);SAM A   1 (-4.2A);SAM A   1 (-3.6A)","0.66A","4fzvA-3douA:8.9","4fzvA-3douA:19.59"],["4N48_A_SAMA601_1","CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",4,"ALA A  22;GLY A  51;ASP A  83;ASP A 111","SAM A   1 (-3.3A);SAM A   1 (-3.2A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.36A","4n48A-3douA:16.4","4n48A-3douA:19.90"],["4N48_B_SAMB601_1","CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",4,"PRO A  49;GLY A  51;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.35A","4n48B-3douA:16.3","4n48B-3douA:19.90"],["4N49_A_SAMA601_0","CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"ALA A  22;PRO A  49;GLY A  50;LEU A  68;ILE A  84","SAM A   1 (-3.3A);SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-4.2A);SAM A   1 (-3.9A)","0.63A","4n49A-3douA:16.0","4n49A-3douA:19.90"],["4OK1_A_198A1001_1","ANDROGEN RECEPTOR","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;MET A  71;THR A  53;ILE A  63;VAL A  77","SAM A   1 (-3.5A);None;None;None;None","1.15A","4ok1A-3douA:undetectable","4ok1A-3douA:22.71"],["4OKW_A_198A1001_1","ANDROGEN RECEPTOR","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;MET A  71;THR A  53;ILE A  63;VAL A  77","SAM A   1 (-3.5A);None;None;None;None","1.17A","4okwA-3douA:undetectable","4okwA-3douA:22.71"],["4PGH_A_SAMA401_0","CAFFEIC ACID O-METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"SER A  20;GLY A  46;ASP A  67;LEU A  68;ASP A  83","SAM A   1 ( 4.5A);SAM A   1 (-3.5A);SAM A   1 (-2.7A);SAM A   1 (-4.2A);SAM A   1 (-3.6A)","1.11A","4pghA-3douA:11.0","4pghA-3douA:18.26"],["4PGH_B_SAMB401_0","CAFFEIC ACID O-METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"SER A  20;GLY A  46;ASP A  67;LEU A  68;ASP A  83","SAM A   1 ( 4.5A);SAM A   1 (-3.5A);SAM A   1 (-2.7A);SAM A   1 (-4.2A);SAM A   1 (-3.6A)","1.24A","4pghB-3douA:10.9","4pghB-3douA:18.26"],["4PGH_C_SAMC401_0","CAFFEIC ACID O-METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"SER A  20;GLY A  46;ASP A  67;LEU A  68;ASP A  83","SAM A   1 ( 4.5A);SAM A   1 (-3.5A);SAM A   1 (-2.7A);SAM A   1 (-4.2A);SAM A   1 (-3.6A)","1.12A","4pghC-3douA:11.7","4pghC-3douA:18.26"],["4UCI_A_SAMA2409_0","RNA-DIRECTED RNA POLYMERASE L","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  50;LEU A  68;ALA A 112;LYS A 151","SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-4.2A);SAM A   1 (-3.7A);SAM A   1 (-3.5A)","0.58A","4uciA-3douA:8.8","4uciA-3douA:20.52"],["4UCI_B_SAMB2409_0","RNA-DIRECTED RNA POLYMERASE L","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  50;LEU A  68;ALA A 112;LYS A 151","SAM A   1 (-3.5A);SAM A   1 (-3.8A);SAM A   1 (-4.2A);SAM A   1 (-3.7A);SAM A   1 (-3.5A)","0.59A","4uciB-3douA:8.7","4uciB-3douA:20.52"],["5E9Q_A_SAMA301_0","GENOME POLYPROTEIN","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.47A","5e9qA-3douA:13.7","5e9qA-3douA:20.00"],["5E9Q_C_SAMC4000_0","GENOME POLYPROTEIN","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.50A","5e9qC-3douA:13.7","5e9qC-3douA:20.00"],["5EC8_A_SAMA301_0","GENOME POLYPROTEIN","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"SER A  20;GLY A  46;GLY A  51;TRP A  52;ASP A 111","SAM A   1 ( 4.5A);SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.7A)","0.75A","5ec8A-3douA:13.8","5ec8A-3douA:19.13"],["5EC8_C_SAMC4000_0","GENOME POLYPROTEIN","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.42A","5ec8C-3douA:13.6","5ec8C-3douA:19.13"],["5EHG_A_SAMA301_0","RNA-DIRECTED RNA POLYMERASE NS5","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.47A","5ehgA-3douA:13.8","5ehgA-3douA:19.13"],["5EHI_A_SAMA4001_0","NS5 METHYLTRANSFERASE DENGUE VIRUS","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.49A","5ehiA-3douA:13.7","5ehiA-3douA:19.13"],["5EHI_C_SAMC4000_0","NS5 METHYLTRANSFERASE DENGUE VIRUS","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.45A","5ehiC-3douA:13.9","5ehiC-3douA:undetectable"],["5EIF_A_SAMA301_0","GENOME POLYPROTEIN","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.48A","5eifA-3douA:13.7","5eifA-3douA:19.13"],["5EIF_C_SAMC4000_0","GENOME POLYPROTEIN","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.45A","5eifC-3douA:13.8","5eifC-3douA:19.13"],["5EIW_A_SAMA301_0","NS5 METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.50A","5eiwA-3douA:13.8","5eiwA-3douA:19.13"],["5EIW_C_SAMC4000_0","NS5 METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.48A","5eiwC-3douA:13.6","5eiwC-3douA:19.13"],["5EKX_A_SAMA301_0","NS5 METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.46A","5ekxA-3douA:13.8","5ekxA-3douA:undetectable"],["5IKM_A_SAMA311_0","NS5 METHYL TRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.48A","5ikmA-3douA:13.9","5ikmA-3douA:17.83"],["5J4N_B_AG2B501_1","ARGININE\/AGMATINE ANTIPORTER","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",4,"ILE A  64;GLY A  50;MET A  71;ILE A  63","None;SAM A   1 (-3.8A);None;None","0.82A","5j4nB-3douA:undetectable","5j4nB-3douA:19.27"],["5KQS_A_SAMA307_0","GENOME POLYPROTEIN","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.37A","5kqsA-3douA:14.0","5kqsA-3douA:19.78"],["5NJV_A_SAMA301_0","NS5","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.45A","5njvA-3douA:13.9","5njvA-3douA:19.85"],["5NJV_B_SAMB301_0","NS5","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.44A","5njvB-3douA:13.9","5njvB-3douA:19.85"],["5WWS_A_SAMA501_0","PUTATIVE METHYLTRANSFERASE NSUN6","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"PRO A  49;GLY A  51;ASP A  67;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-2.7A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.64A","5wwsA-3douA:10.0","5wwsA-3douA:18.03"],["5WWS_B_SAMB501_0","PUTATIVE METHYLTRANSFERASE NSUN6","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"PRO A  49;GLY A  51;ASP A  67;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-2.7A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.66A","5wwsB-3douA:9.8","5wwsB-3douA:18.03"],["5WZ1_A_SAMA601_0","NS5 METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.50A","5wz1A-3douA:13.8","5wz1A-3douA:20.00"],["5WZ1_C_SAMC601_0","NS5 METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.51A","5wz1C-3douA:13.8","5wz1C-3douA:20.00"],["5WZ1_D_SAMD601_0","NS5 METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.56A","5wz1D-3douA:13.9","5wz1D-3douA:20.00"],["5WZ1_E_SAME601_0","NS5 METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.48A","5wz1E-3douA:13.8","5wz1E-3douA:20.00"],["5WZ1_F_SAMF601_0","NS5 METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.57A","5wz1F-3douA:13.9","5wz1F-3douA:20.00"],["5WZ1_G_SAMG601_0","NS5 METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.52A","5wz1G-3douA:13.8","5wz1G-3douA:20.00"],["5WZ1_H_SAMH601_0","NS5 METHYLTRANSFERASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.52A","5wz1H-3douA:13.8","5wz1H-3douA:20.00"],["5WZ2_A_SAMA601_0","NS5 MTASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.41A","5wz2A-3douA:13.8","5wz2A-3douA:20.00"],["5WZ2_B_SAMB601_0","NS5 MTASE","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;TRP A  52;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.0A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.44A","5wz2B-3douA:13.9","5wz2B-3douA:20.00"],["5YN6_A_SAMA401_0","NSP16 PROTEIN","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",5,"GLY A  46;GLY A  51;LEU A  68;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-4.2A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.97A","5yn6A-3douA:7.6","5yn6A-3douA:20.50"],["5YNI_A_SAMA401_0","NSP16 PROTEIN","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",6,"GLY A  46;GLY A  51;ASP A  67;LEU A  68;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-2.7A);SAM A   1 (-4.2A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","1.01A","5yniA-3douA:12.9","5yniA-3douA:20.50"],["5YNM_A_SAMA401_0","NSP16 PROTEIN","3dou","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","Thermoplasma volcanium",6,"GLY A  46;GLY A  51;ASP A  67;LEU A  68;ASP A  83;ASP A 111","SAM A   1 (-3.5A);SAM A   1 (-3.2A);SAM A   1 (-2.7A);SAM A   1 (-4.2A);SAM A   1 (-3.6A);SAM A   1 (-3.7A)","0.98A","5ynmA-3douA:13.0","5ynmA-3douA:20.50"]]