SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dp7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 ALA A  66
GLY A  58
ALA A  67
THR A  60
ILE A  56
 None
 1.20A 1gtnB-3dp7A:
undetectable
1gtnC-3dp7A:
undetectable		 1gtnB-3dp7A:
15.60
1gtnC-3dp7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		3 / 3 ILE A 267
ASP A 324
PHE A 320
 None
 0.65A 1uwjB-3dp7A:
undetectable		 1uwjB-3dp7A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		3 / 3 ASN A  98
TRP A  94
GLN A  42
 None
 1.40A 1xoqA-3dp7A:
undetectable		 1xoqA-3dp7A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		4 / 8 ASP A 323
SER A 322
ILE A 326
ASP A 291
 None
 0.98A 2xadA-3dp7A:
5.5		 2xadA-3dp7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		4 / 8 ASP A 323
SER A 322
ILE A 326
ASP A 291
 None
 1.01A 2xadB-3dp7A:
5.3		 2xadB-3dp7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		4 / 8 ASP A 323
SER A 322
ILE A 326
ASP A 291
 None
 1.01A 2xadC-3dp7A:
5.4		 2xadC-3dp7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		4 / 8 ASP A 323
SER A 322
ILE A 326
ASP A 291
 None
 1.00A 2xadD-3dp7A:
5.5		 2xadD-3dp7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		4 / 4 ILE A 285
GLN A 256
ILE A 269
LEU A 302
 None
 1.35A 3dzyD-3dp7A:
undetectable		 3dzyD-3dp7A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		3 / 3 TRP A 193
VAL A 209
TRP A 253
 None
 1.43A 3zq8A-3dp7A:
undetectable
3zq8B-3dp7A:
undetectable		 3zq8A-3dp7A:
4.12
3zq8B-3dp7A:
4.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		4 / 8 ASP A 185
ILE A 186
GLY A 187
PHE A 257
 None
 0.70A 4acbB-3dp7A:
3.2
4acbC-3dp7A:
3.7		 4acbB-3dp7A:
19.76
4acbC-3dp7A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		4 / 6 HIS A 110
GLU A 107
ASP A 111
SER A 155
 None
 1.36A 4apjA-3dp7A:
2.1
4apjP-3dp7A:
undetectable		 4apjA-3dp7A:
21.37
4apjP-3dp7A:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 ARG A 182
VAL A 273
GLY A 187
ILE A 208
PRO A 246
 None
 1.07A 4dqcA-3dp7A:
undetectable		 4dqcA-3dp7A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 11 SER A 164
GLY A 187
GLY A 188
ASP A 210
LEU A 211
 None
 1.14A 4pghA-3dp7A:
21.3		 4pghA-3dp7A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 12 SER A 164
GLY A 187
GLY A 188
ASP A 210
LEU A 211
 None
 1.12A 4pghD-3dp7A:
17.4		 4pghD-3dp7A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 GLY A  58
ALA A  67
THR A  60
ILE A  56
ALA A  66
 None
 1.20A 5eeuO-3dp7A:
undetectable
5eeuP-3dp7A:
undetectable		 5eeuO-3dp7A:
15.60
5eeuP-3dp7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 GLY A  58
ALA A  67
THR A  60
ILE A  56
ALA A  66
 None
 1.20A 5eeuQ-3dp7A:
undetectable
5eeuR-3dp7A:
undetectable		 5eeuQ-3dp7A:
15.60
5eeuR-3dp7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 GLY A  58
ALA A  67
THR A  60
ILE A  56
ALA A  66
 None
 1.20A 5eevO-3dp7A:
undetectable
5eevP-3dp7A:
undetectable		 5eevO-3dp7A:
15.60
5eevP-3dp7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 GLY A  58
ALA A  67
THR A  60
ILE A  56
ALA A  66
 None
 1.20A 5eewO-3dp7A:
undetectable
5eewP-3dp7A:
undetectable		 5eewO-3dp7A:
15.60
5eewP-3dp7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 GLY A  58
ALA A  67
THR A  60
ILE A  56
ALA A  66
 None
 1.20A 5eexO-3dp7A:
undetectable
5eexP-3dp7A:
undetectable		 5eexO-3dp7A:
15.60
5eexP-3dp7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 GLY A  58
ALA A  67
THR A  60
ILE A  56
ALA A  66
 None
 1.20A 5eeyO-3dp7A:
undetectable
5eeyP-3dp7A:
undetectable		 5eeyO-3dp7A:
15.60
5eeyP-3dp7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 GLY A  58
ALA A  67
THR A  60
ILE A  56
ALA A  66
 None
 1.20A 5eezO-3dp7A:
undetectable
5eezP-3dp7A:
undetectable		 5eezO-3dp7A:
15.60
5eezP-3dp7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 GLY A  58
ALA A  67
THR A  60
ILE A  56
ALA A  66
 None
 1.20A 5ef0O-3dp7A:
undetectable
5ef0P-3dp7A:
undetectable		 5ef0O-3dp7A:
15.60
5ef0P-3dp7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 GLY A  58
ALA A  67
THR A  60
ILE A  56
ALA A  66
 None
 1.20A 5ef1O-3dp7A:
undetectable
5ef1P-3dp7A:
undetectable		 5ef1O-3dp7A:
15.60
5ef1P-3dp7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 GLY A  58
ALA A  67
THR A  60
ILE A  56
ALA A  66
 None
 1.20A 5ef2O-3dp7A:
undetectable
5ef2P-3dp7A:
undetectable		 5ef2O-3dp7A:
15.60
5ef2P-3dp7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 GLY A  58
ALA A  67
THR A  60
ILE A  56
ALA A  66
 None
 1.20A 5ef3O-3dp7A:
undetectable
5ef3P-3dp7A:
undetectable		 5ef3O-3dp7A:
15.60
5ef3P-3dp7A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 12 VAL A  69
ALA A  67
THR A  79
PHE A  41
ILE A  40
 None
 1.44A 5hgcA-3dp7A:
undetectable		 5hgcA-3dp7A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3dp7 SAM-DEPENDENT
METHYLTRANSFERASE
(Bacteroides
vulgatus) 		4 / 7 HIS A 347
ARG A 292
HIS A 321
ASP A 341
 None
 1.07A 6mn4E-3dp7A:
undetectable		 6mn4E-3dp7A:
20.82