SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dqg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		4 / 5 LEU A 484
ASP A 515
VAL A 461
ILE A 487
 None
 0.98A 2aoiB-3dqgA:
undetectable		 2aoiB-3dqgA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 12 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.90A 2avvE-3dqgA:
undetectable		 2avvE-3dqgA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 12 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.93A 2f80A-3dqgA:
undetectable		 2f80A-3dqgA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 12 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.92A 2f80B-3dqgA:
undetectable		 2f80B-3dqgA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 12 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.96A 2hs2B-3dqgA:
undetectable		 2hs2B-3dqgA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 12 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.98A 2pymA-3dqgA:
undetectable		 2pymA-3dqgA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 12 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.96A 2pymB-3dqgA:
undetectable		 2pymB-3dqgA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 12 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.99A 2pynA-3dqgA:
undetectable		 2pynA-3dqgA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 12 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.99A 2pynB-3dqgA:
undetectable		 2pynB-3dqgA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 12 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.97A 2q63B-3dqgA:
undetectable		 2q63B-3dqgA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 12 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.92A 2qakB-3dqgA:
undetectable		 2qakB-3dqgA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		4 / 8 GLN A 522
VAL A 497
GLY A 519
GLY A 517
 None
 0.78A 2vinA-3dqgA:
undetectable		 2vinA-3dqgA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 12 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.97A 3d1xB-3dqgA:
undetectable		 3d1xB-3dqgA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 10 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.91A 3em3A-3dqgA:
undetectable		 3em3A-3dqgA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 12 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 1.00A 3oxcB-3dqgA:
undetectable		 3oxcB-3dqgA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 12 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.98A 3oxxC-3dqgA:
undetectable		 3oxxC-3dqgA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 12 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.97A 3tkgA-3dqgA:
undetectable		 3tkgA-3dqgA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		5 / 11 LEU A 484
ASP A 515
GLY A 517
VAL A 461
ILE A 487
 None
 0.91A 4hlaB-3dqgA:
undetectable		 4hlaB-3dqgA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3dqg HEAT SHOCK 70 KDA
PROTEIN F
(Caenorhabditis
elegans) 		4 / 8 ILE A 432
GLY A 431
PHE A 482
ASN A 476
 None
 0.94A 5hieD-3dqgA:
undetectable		 5hieD-3dqgA:
19.33