SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dqp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 11 LEU A  61
VAL A  46
VAL A   6
TYR A  28
GLY A  30
None
1.23A 1fkpA-3dqpA:
undetectable
1fkpA-3dqpA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 THR A 187
HIS A 189
ALA A 207
THR A 180
ILE A 164
None
1.45A 1gtfE-3dqpA:
undetectable
1gtfF-3dqpA:
undetectable
1gtfE-3dqpA:
18.06
1gtfF-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 THR A 187
HIS A 189
ALA A 207
THR A 180
ILE A 164
None
1.39A 1gtnG-3dqpA:
undetectable
1gtnH-3dqpA:
undetectable
1gtnG-3dqpA:
18.06
1gtnH-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 10 LEU A  61
VAL A  46
VAL A   6
TYR A  28
GLY A  30
None
1.20A 1lw0A-3dqpA:
undetectable
1lw0A-3dqpA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 11 LEU A  61
VAL A  46
VAL A   6
TYR A  28
GLY A  30
None
1.09A 1lwcA-3dqpA:
undetectable
1lwcA-3dqpA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 12 LEU A  16
ILE A 148
ILE A  68
TYR A  25
MET A 186
None
1.46A 1osvB-3dqpA:
undetectable
1osvB-3dqpA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 HIS A 189
ALA A 207
THR A 180
ILE A 164
THR A 187
None
1.42A 1utdD-3dqpA:
undetectable
1utdE-3dqpA:
undetectable
1utdD-3dqpA:
18.06
1utdE-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 HIS A 189
ALA A 207
THR A 180
ILE A 164
THR A 187
None
1.40A 1utdG-3dqpA:
undetectable
1utdH-3dqpA:
undetectable
1utdG-3dqpA:
18.06
1utdH-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 7 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.00A 1v55C-3dqpA:
undetectable
1v55N-3dqpA:
undetectable
1v55P-3dqpA:
undetectable
1v55C-3dqpA:
20.86
1v55N-3dqpA:
17.95
1v55P-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 7 LEU A  20
ASP A 179
THR A 180
HIS A 189
None
1.22A 1v55C-3dqpA:
undetectable
1v55N-3dqpA:
undetectable
1v55P-3dqpA:
undetectable
1v55C-3dqpA:
20.86
1v55N-3dqpA:
17.95
1v55P-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VRT_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 LEU A  61
VAL A  46
VAL A   6
TYR A  28
GLY A  30
None
1.12A 1vrtA-3dqpA:
undetectable
1vrtA-3dqpA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 12 ALA A 129
GLY A  75
GLY A  74
SER A 105
LEU A 153
None
0.89A 1ya4A-3dqpA:
3.4
1ya4A-3dqpA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 VAL A 185
ASP A 188
TYR A  25
LEU A  20
None
0.92A 1z2bB-3dqpA:
6.3
1z2bB-3dqpA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 6 ALA A  66
TYR A  25
ILE A 102
ILE A   3
None
1.19A 2dcfA-3dqpA:
undetectable
2dcfA-3dqpA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HND_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 10 LEU A  61
VAL A  46
VAL A   6
TYR A  28
GLY A  30
None
1.14A 2hndA-3dqpA:
undetectable
2hndA-3dqpA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HNY_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 10 LEU A  61
VAL A  46
VAL A   6
TYR A  28
GLY A  30
None
1.10A 2hnyA-3dqpA:
undetectable
2hnyA-3dqpA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
3 / 3 ASP A  24
TYR A  25
LYS A 182
None
0.75A 2othA-3dqpA:
undetectable
2othA-3dqpA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.09A 2y69C-3dqpA:
undetectable
2y69N-3dqpA:
undetectable
2y69P-3dqpA:
undetectable
2y69C-3dqpA:
20.86
2y69N-3dqpA:
17.95
2y69P-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 12 ILE A 148
THR A 187
ARG A 100
THR A 146
PRO A 150
None
1.27A 2yzqA-3dqpA:
undetectable
2yzqA-3dqpA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 7 ALA A  66
TYR A  25
ILE A 102
ILE A   3
None
1.15A 2zm7A-3dqpA:
undetectable
2zm7A-3dqpA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZS9_A_PAUA603_0
(PANTOTHENATE KINASE)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 6 VAL A   6
ASP A  49
LYS A  88
ASN A  69
None
1.50A 2zs9A-3dqpA:
undetectable
2zs9A-3dqpA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.01A 3ablA-3dqpA:
undetectable
3ablC-3dqpA:
undetectable
3ablP-3dqpA:
undetectable
3ablA-3dqpA:
17.95
3ablC-3dqpA:
20.86
3ablP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.03A 3ablC-3dqpA:
undetectable
3ablN-3dqpA:
undetectable
3ablP-3dqpA:
undetectable
3ablC-3dqpA:
20.86
3ablN-3dqpA:
17.95
3ablP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.05A 3abmA-3dqpA:
undetectable
3abmC-3dqpA:
undetectable
3abmP-3dqpA:
undetectable
3abmA-3dqpA:
17.95
3abmC-3dqpA:
20.86
3abmP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.01A 3asnC-3dqpA:
undetectable
3asnN-3dqpA:
undetectable
3asnP-3dqpA:
undetectable
3asnC-3dqpA:
20.86
3asnN-3dqpA:
17.95
3asnP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.05A 3asoA-3dqpA:
undetectable
3asoC-3dqpA:
undetectable
3asoP-3dqpA:
undetectable
3asoA-3dqpA:
17.95
3asoC-3dqpA:
20.86
3asoP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.02A 3asoC-3dqpA:
undetectable
3asoN-3dqpA:
undetectable
3asoP-3dqpA:
undetectable
3asoC-3dqpA:
20.86
3asoN-3dqpA:
17.95
3asoP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 12 LEU A  17
GLY A   7
GLY A  13
ALA A  31
LEU A  89
None
1.02A 3dh0A-3dqpA:
5.5
3dh0A-3dqpA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 12 LEU A  17
GLY A   7
GLY A  13
ALA A  31
LEU A  89
None
1.09A 3dh0B-3dqpA:
5.4
3dh0B-3dqpA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 10 LEU A  61
VAL A  46
VAL A   6
TYR A  28
GLY A  30
None
1.08A 3qipA-3dqpA:
undetectable
3qipA-3dqpA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.05A 3wg7A-3dqpA:
undetectable
3wg7C-3dqpA:
undetectable
3wg7P-3dqpA:
undetectable
3wg7A-3dqpA:
17.95
3wg7C-3dqpA:
20.86
3wg7P-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.02A 3wg7C-3dqpA:
undetectable
3wg7N-3dqpA:
undetectable
3wg7P-3dqpA:
undetectable
3wg7C-3dqpA:
20.86
3wg7N-3dqpA:
17.95
3wg7P-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.02A 3x2qA-3dqpA:
undetectable
3x2qC-3dqpA:
undetectable
3x2qP-3dqpA:
undetectable
3x2qA-3dqpA:
17.95
3x2qC-3dqpA:
20.86
3x2qP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.02A 3x2qC-3dqpA:
undetectable
3x2qN-3dqpA:
undetectable
3x2qP-3dqpA:
undetectable
3x2qC-3dqpA:
20.86
3x2qN-3dqpA:
17.95
3x2qP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 4 SER A  19
SER A  15
GLU A 157
ASP A 179
None
1.34A 4ymgA-3dqpA:
3.1
4ymgA-3dqpA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.05A 5b1aA-3dqpA:
undetectable
5b1aC-3dqpA:
undetectable
5b1aP-3dqpA:
undetectable
5b1aA-3dqpA:
17.95
5b1aC-3dqpA:
20.86
5b1aP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.02A 5b1bA-3dqpA:
undetectable
5b1bC-3dqpA:
undetectable
5b1bP-3dqpA:
undetectable
5b1bA-3dqpA:
17.95
5b1bC-3dqpA:
20.86
5b1bP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.01A 5b3sA-3dqpA:
undetectable
5b3sC-3dqpA:
undetectable
5b3sP-3dqpA:
undetectable
5b3sA-3dqpA:
17.95
5b3sC-3dqpA:
20.86
5b3sP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 THR A 187
HIS A 189
ALA A 207
THR A 180
ILE A 164
None
1.40A 5eeuB-3dqpA:
undetectable
5eeuC-3dqpA:
undetectable
5eeuB-3dqpA:
18.06
5eeuC-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 THR A 187
HIS A 189
ALA A 207
THR A 180
ILE A 164
None
1.40A 5eevB-3dqpA:
undetectable
5eevC-3dqpA:
undetectable
5eevB-3dqpA:
18.06
5eevC-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 THR A 187
HIS A 189
ALA A 207
THR A 180
ILE A 164
None
1.40A 5eewB-3dqpA:
undetectable
5eewC-3dqpA:
undetectable
5eewB-3dqpA:
18.06
5eewC-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 THR A 187
HIS A 189
ALA A 207
THR A 180
ILE A 164
None
1.40A 5eexB-3dqpA:
undetectable
5eexC-3dqpA:
undetectable
5eexB-3dqpA:
18.06
5eexC-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 THR A 187
HIS A 189
ALA A 207
THR A 180
ILE A 164
None
1.41A 5eeyB-3dqpA:
undetectable
5eeyC-3dqpA:
undetectable
5eeyB-3dqpA:
18.06
5eeyC-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 THR A 187
HIS A 189
ALA A 207
THR A 180
ILE A 164
None
1.41A 5eezB-3dqpA:
undetectable
5eezC-3dqpA:
undetectable
5eezB-3dqpA:
18.06
5eezC-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 THR A 187
HIS A 189
ALA A 207
THR A 180
ILE A 164
None
1.41A 5ef0B-3dqpA:
undetectable
5ef0C-3dqpA:
undetectable
5ef0B-3dqpA:
18.06
5ef0C-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 THR A 187
HIS A 189
ALA A 207
THR A 180
ILE A 164
None
1.41A 5ef1B-3dqpA:
undetectable
5ef1C-3dqpA:
undetectable
5ef1B-3dqpA:
18.06
5ef1C-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 THR A 187
HIS A 189
ALA A 207
THR A 180
ILE A 164
None
1.41A 5ef2B-3dqpA:
undetectable
5ef2C-3dqpA:
undetectable
5ef2B-3dqpA:
18.06
5ef2C-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 10 THR A 187
HIS A 189
ALA A 207
THR A 180
ILE A 164
None
1.43A 5ef2D-3dqpA:
undetectable
5ef2E-3dqpA:
undetectable
5ef2D-3dqpA:
18.06
5ef2E-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 9 THR A 187
HIS A 189
ALA A 207
THR A 180
ILE A 164
None
1.41A 5ef3B-3dqpA:
undetectable
5ef3C-3dqpA:
undetectable
5ef3B-3dqpA:
18.06
5ef3C-3dqpA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
5 / 11 LEU A  61
VAL A  46
VAL A   6
TYR A  28
GLY A  30
None
1.05A 5hbmA-3dqpA:
undetectable
5hbmA-3dqpA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
0.97A 5iy5C-3dqpA:
undetectable
5iy5N-3dqpA:
undetectable
5iy5P-3dqpA:
undetectable
5iy5C-3dqpA:
20.65
5iy5N-3dqpA:
17.95
5iy5P-3dqpA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 LEU A  20
ASP A 179
THR A 180
HIS A 189
None
1.18A 5iy5C-3dqpA:
undetectable
5iy5N-3dqpA:
undetectable
5iy5P-3dqpA:
undetectable
5iy5C-3dqpA:
20.65
5iy5N-3dqpA:
17.95
5iy5P-3dqpA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 7 GLY A   7
GLY A  13
SER A  15
LEU A  20
None
0.79A 5izfA-3dqpA:
undetectable
5izfA-3dqpA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
0.99A 5w97A-3dqpA:
undetectable
5w97C-3dqpA:
undetectable
5w97c-3dqpA:
undetectable
5w97A-3dqpA:
17.95
5w97C-3dqpA:
20.86
5w97c-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 7 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
0.99A 5w97C-3dqpA:
undetectable
5w97a-3dqpA:
undetectable
5w97c-3dqpA:
undetectable
5w97C-3dqpA:
20.86
5w97a-3dqpA:
17.95
5w97c-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.02A 5wauA-3dqpA:
undetectable
5wauC-3dqpA:
undetectable
5wauc-3dqpA:
undetectable
5wauA-3dqpA:
17.95
5wauC-3dqpA:
20.86
5wauc-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 7 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.04A 5wauC-3dqpA:
undetectable
5waua-3dqpA:
undetectable
5wauc-3dqpA:
undetectable
5wauC-3dqpA:
20.86
5waua-3dqpA:
17.95
5wauc-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.07A 5x19A-3dqpA:
undetectable
5x19C-3dqpA:
undetectable
5x19P-3dqpA:
undetectable
5x19A-3dqpA:
17.95
5x19C-3dqpA:
20.86
5x19P-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 7 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.03A 5x1bA-3dqpA:
undetectable
5x1bC-3dqpA:
undetectable
5x1bP-3dqpA:
undetectable
5x1bA-3dqpA:
17.95
5x1bC-3dqpA:
20.86
5x1bP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 7 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.02A 5x1fA-3dqpA:
undetectable
5x1fC-3dqpA:
undetectable
5x1fP-3dqpA:
undetectable
5x1fA-3dqpA:
17.95
5x1fC-3dqpA:
20.86
5x1fP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.03A 5xdqA-3dqpA:
undetectable
5xdqC-3dqpA:
undetectable
5xdqP-3dqpA:
undetectable
5xdqA-3dqpA:
17.95
5xdqC-3dqpA:
20.86
5xdqP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.01A 5xdqC-3dqpA:
undetectable
5xdqN-3dqpA:
undetectable
5xdqP-3dqpA:
undetectable
5xdqC-3dqpA:
20.86
5xdqN-3dqpA:
17.95
5xdqP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.02A 5xdxC-3dqpA:
undetectable
5xdxN-3dqpA:
undetectable
5xdxP-3dqpA:
undetectable
5xdxC-3dqpA:
20.58
5xdxN-3dqpA:
17.95
5xdxP-3dqpA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.03A 5z84A-3dqpA:
undetectable
5z84C-3dqpA:
undetectable
5z84P-3dqpA:
undetectable
5z84A-3dqpA:
17.95
5z84C-3dqpA:
20.86
5z84P-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 7 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.05A 5z84C-3dqpA:
undetectable
5z84N-3dqpA:
undetectable
5z84P-3dqpA:
undetectable
5z84C-3dqpA:
20.86
5z84N-3dqpA:
17.95
5z84P-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.04A 5z85A-3dqpA:
undetectable
5z85C-3dqpA:
undetectable
5z85P-3dqpA:
undetectable
5z85A-3dqpA:
17.95
5z85C-3dqpA:
20.86
5z85P-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 7 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.03A 5z85C-3dqpA:
undetectable
5z85N-3dqpA:
undetectable
5z85P-3dqpA:
undetectable
5z85C-3dqpA:
20.86
5z85N-3dqpA:
17.95
5z85P-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 7 LEU A  20
ASP A 179
THR A 180
HIS A 189
None
1.26A 5z85C-3dqpA:
undetectable
5z85N-3dqpA:
undetectable
5z85P-3dqpA:
undetectable
5z85C-3dqpA:
20.86
5z85N-3dqpA:
17.95
5z85P-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.04A 5z86A-3dqpA:
undetectable
5z86C-3dqpA:
undetectable
5z86P-3dqpA:
undetectable
5z86A-3dqpA:
17.95
5z86C-3dqpA:
20.86
5z86P-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.05A 5z86C-3dqpA:
undetectable
5z86N-3dqpA:
undetectable
5z86P-3dqpA:
undetectable
5z86C-3dqpA:
20.86
5z86N-3dqpA:
17.95
5z86P-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.06A 5zcoA-3dqpA:
undetectable
5zcoC-3dqpA:
undetectable
5zcoP-3dqpA:
undetectable
5zcoA-3dqpA:
17.95
5zcoC-3dqpA:
20.86
5zcoP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.04A 5zcoC-3dqpA:
undetectable
5zcoN-3dqpA:
undetectable
5zcoP-3dqpA:
undetectable
5zcoC-3dqpA:
20.86
5zcoN-3dqpA:
17.95
5zcoP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.06A 5zcpA-3dqpA:
undetectable
5zcpC-3dqpA:
undetectable
5zcpP-3dqpA:
undetectable
5zcpA-3dqpA:
17.95
5zcpC-3dqpA:
20.86
5zcpP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.07A 5zcpC-3dqpA:
undetectable
5zcpN-3dqpA:
undetectable
5zcpP-3dqpA:
undetectable
5zcpC-3dqpA:
20.86
5zcpN-3dqpA:
17.95
5zcpP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.04A 5zcqA-3dqpA:
undetectable
5zcqC-3dqpA:
undetectable
5zcqP-3dqpA:
undetectable
5zcqA-3dqpA:
17.95
5zcqC-3dqpA:
20.86
5zcqP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 8 LEU A  16
ASP A 179
THR A 180
HIS A 189
None
1.03A 6nknC-3dqpA:
undetectable
6nknN-3dqpA:
undetectable
6nknP-3dqpA:
undetectable
6nknC-3dqpA:
20.86
6nknN-3dqpA:
17.95
6nknP-3dqpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3dqp OXIDOREDUCTASE YLBE
(Lactococcus
lactis)
4 / 7 ASP A 179
THR A 180
HIS A 189
LEU A  16
None
1.06A 6nmfA-3dqpA:
undetectable
6nmfC-3dqpA:
undetectable
6nmfP-3dqpA:
undetectable
6nmfA-3dqpA:
17.95
6nmfC-3dqpA:
20.86
6nmfP-3dqpA:
20.86