SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dqv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 8 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.86A 1v54P-3dqvC:
undetectable
1v54W-3dqvC:
undetectable		 1v54P-3dqvC:
20.37
1v54W-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 7 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.91A 1v55P-3dqvC:
undetectable
1v55W-3dqvC:
undetectable		 1v55P-3dqvC:
20.37
1v55W-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 8 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.86A 2dyrP-3dqvC:
undetectable
2dyrW-3dqvC:
undetectable		 2dyrP-3dqvC:
20.37
2dyrW-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 7 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.84A 2dysC-3dqvC:
undetectable
2dysJ-3dqvC:
undetectable		 2dysC-3dqvC:
20.37
2dysJ-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 7 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.84A 2dysP-3dqvC:
undetectable
2dysW-3dqvC:
undetectable		 2dysP-3dqvC:
20.37
2dysW-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 7 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.91A 2eijP-3dqvC:
undetectable
2eijW-3dqvC:
undetectable		 2eijP-3dqvC:
20.37
2eijW-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3dqv CULLIN-5
(Homo
sapiens) 		5 / 12 VAL C1595
ILE C1686
LEU C1674
VAL C1647
LEU C1603
 None
 1.19A 2jn3A-3dqvC:
undetectable		 2jn3A-3dqvC:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 8 LEU C1531
ALA C1535
HIS C1574
MET C1577
 None
 1.05A 2wekA-3dqvC:
undetectable		 2wekA-3dqvC:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 3dqv CULLIN-5
(Homo
sapiens) 		3 / 3 SER C1730
ARG C1726
GLN C1733
 None
 1.02A 2xnrA-3dqvC:
undetectable		 2xnrA-3dqvC:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 7 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.83A 2zxwC-3dqvC:
undetectable
2zxwJ-3dqvC:
undetectable		 2zxwC-3dqvC:
20.37
2zxwJ-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 6 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.90A 2zxwP-3dqvC:
undetectable
2zxwW-3dqvC:
undetectable		 2zxwP-3dqvC:
20.37
2zxwW-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 6 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.79A 3ag1C-3dqvC:
undetectable
3ag1J-3dqvC:
undetectable		 3ag1C-3dqvC:
20.37
3ag1J-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 8 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.86A 3ag4C-3dqvC:
undetectable
3ag4J-3dqvC:
undetectable		 3ag4C-3dqvC:
20.37
3ag4J-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 7 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.89A 3ag4P-3dqvC:
undetectable
3ag4W-3dqvC:
undetectable		 3ag4P-3dqvC:
20.37
3ag4W-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 8 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.90A 3asoC-3dqvC:
undetectable
3asoJ-3dqvC:
undetectable		 3asoC-3dqvC:
20.37
3asoJ-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 3dqv CULLIN-5
(Homo
sapiens) 		5 / 12 LEU C1434
LEU C1416
ASP C1413
PHE C1450
SER C1402
 None
 1.21A 3ko0K-3dqvC:
undetectable
3ko0L-3dqvC:
undetectable
3ko0S-3dqvC:
undetectable
3ko0T-3dqvC:
undetectable		 3ko0K-3dqvC:
13.84
3ko0L-3dqvC:
13.84
3ko0S-3dqvC:
13.84
3ko0T-3dqvC:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 6 VAL C1602
VAL C1647
ILE C1582
ARG C1632
 None
 1.02A 3ms9A-3dqvC:
undetectable		 3ms9A-3dqvC:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 6 VAL C1602
VAL C1647
ILE C1582
ARG C1632
 None
 1.05A 3mssA-3dqvC:
undetectable		 3mssA-3dqvC:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 6 VAL C1602
VAL C1647
ILE C1582
ARG C1632
 None
 1.04A 3mssC-3dqvC:
undetectable		 3mssC-3dqvC:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 6 ILE C1530
ASN C1565
HIS C1566
LEU C1571
 None
 1.02A 3oi8A-3dqvC:
undetectable		 3oi8A-3dqvC:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 6 VAL C1602
VAL C1647
ILE C1582
ARG C1632
 None
 0.84A 3pyyA-3dqvC:
undetectable		 3pyyA-3dqvC:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 3dqv CULLIN-5
(Homo
sapiens) 		6 / 12 PHE C1450
LEU C1408
ALA C1409
LEU C1416
SER C1402
LEU C1493
 None
 1.50A 4dm8B-3dqvC:
undetectable		 4dm8B-3dqvC:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 7 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.95A 5b3sC-3dqvC:
undetectable
5b3sJ-3dqvC:
undetectable		 5b3sC-3dqvC:
20.37
5b3sJ-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 7 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.88A 5iy5C-3dqvC:
undetectable
5iy5J-3dqvC:
undetectable		 5iy5C-3dqvC:
20.68
5iy5J-3dqvC:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3dqv CULLIN-5
(Homo
sapiens) 		3 / 3 HIS C1763
GLU C1762
TRP C1759
 None
 0.76A 5odiD-3dqvC:
undetectable		 5odiD-3dqvC:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3dqv CULLIN-5
(Homo
sapiens) 		3 / 3 HIS C1763
GLU C1762
TRP C1759
 None
 0.75A 5odqD-3dqvC:
undetectable		 5odqD-3dqvC:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3dqv CULLIN-5
(Homo
sapiens) 		3 / 3 HIS C1763
GLU C1762
TRP C1759
 None
 0.74A 5odrD-3dqvC:
undetectable		 5odrD-3dqvC:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3dqv CULLIN-5
(Homo
sapiens) 		5 / 12 ILE C1686
PHE C1672
ASN C1586
LEU C1634
LEU C1688
 None
 1.03A 5xxiA-3dqvC:
undetectable		 5xxiA-3dqvC:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 7 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.92A 5z84C-3dqvC:
undetectable
5z84J-3dqvC:
undetectable		 5z84C-3dqvC:
20.37
5z84J-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3dqv CULLIN-5
(Homo
sapiens) 		4 / 7 LEU C1600
GLN C1599
PHE C1598
LEU C1551
 None
 0.87A 5zcoC-3dqvC:
undetectable
5zcoJ-3dqvC:
undetectable		 5zcoC-3dqvC:
20.37
5zcoJ-3dqvC:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3dqv CULLIN-5
(Homo
sapiens) 		3 / 3 LEU C1643
ASN C1586
LEU C1649
 None
 0.57A 6exiD-3dqvC:
undetectable		 6exiD-3dqvC:
12.53