SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dqy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3dqy TOLUENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		5 / 12 ILE A  58
ILE A  89
THR A  72
VAL A  26
LEU A  54
 CSO  A  69 ( 4.7A)
None
CSO  A  69 ( 3.8A)
None
None
 1.16A 2qo5A-3dqyA:
undetectable		 2qo5A-3dqyA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA500_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3dqy TOLUENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		4 / 4 ALA A  80
HIS A  44
HIS A  64
PRO A  79
 FES  A 107 ( 4.9A)
FES  A 107 (-3.2A)
FES  A 107 (-3.1A)
FES  A 107 ( 4.6A)
 1.22A 3mbgA-3dqyA:
undetectable		 3mbgA-3dqyA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC900_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3dqy TOLUENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		4 / 4 ALA A  80
HIS A  44
HIS A  64
PRO A  79
 FES  A 107 ( 4.9A)
FES  A 107 (-3.2A)
FES  A 107 (-3.1A)
FES  A 107 ( 4.6A)
 1.22A 3mbgC-3dqyA:
undetectable		 3mbgC-3dqyA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_D_DXCD92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3dqy TOLUENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		4 / 5 VAL A  26
GLU A  95
LYS A  90
PHE A  87
 None
 1.38A 3rv5C-3dqyA:
undetectable
3rv5D-3dqyA:
undetectable		 3rv5C-3dqyA:
22.61
3rv5D-3dqyA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 3dqy TOLUENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		4 / 6 CYH A  42
THR A  43
CYH A  61
GLY A  66
 FES  A 107 (-2.3A)
None
FES  A 107 (-2.2A)
FES  A 107 (-3.7A)
 1.38A 3w9tE-3dqyA:
undetectable		 3w9tE-3dqyA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3dqy TOLUENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT
(Pseudomonas
putida) 		4 / 7 THR A  43
VAL A  75
LYS A  82
HIS A  44
 None
None
None
FES  A 107 (-3.2A)
 1.24A 5ecnA-3dqyA:
undetectable		 5ecnA-3dqyA:
11.11