SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ds8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		5 / 12 PHE A 202
ALA A 178
ALA A 176
GLY A 131
LEU A 108
 None
 1.00A 1qabF-3ds8A:
undetectable		 1qabF-3ds8A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		4 / 6 SER A 195
SER A  12
GLN A  70
ASP A 136
 None
SO4  A 255 ( 2.6A)
None
None
 1.42A 2cl5B-3ds8A:
3.3		 2cl5B-3ds8A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		4 / 6 SER A 195
SER A  12
GLN A  70
ASP A 136
 None
SO4  A 255 ( 2.6A)
None
None
 1.41A 2zvjA-3ds8A:
undetectable		 2zvjA-3ds8A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		4 / 8 GLY A 105
GLY A 104
GLY A  11
SER A 132
 None
None
SO4  A 256 ( 3.5A)
None
 0.70A 3d41A-3ds8A:
undetectable		 3d41A-3ds8A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 105
VAL A 128
GLY A  98
GLY A  11
LEU A  19
 None
None
None
SO4  A 256 ( 3.5A)
None
 0.81A 3ku1A-3ds8A:
2.0		 3ku1A-3ds8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 105
VAL A 128
GLY A  98
GLY A  11
LEU A  19
 None
None
None
SO4  A 256 ( 3.5A)
None
 0.80A 3ku1C-3ds8A:
2.5		 3ku1C-3ds8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		4 / 8 GLY A 105
GLY A 131
ILE A 177
LEU A 225
 None
 0.79A 4mwzB-3ds8A:
undetectable		 4mwzB-3ds8A:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		3 / 3 SER A 102
ALA A 129
VAL A 128
 SO4  A 255 (-2.2A)
None
None
 0.54A 4o2bA-3ds8A:
4.4		 4o2bA-3ds8A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		3 / 3 SER A 102
ALA A 129
VAL A 128
 SO4  A 255 (-2.2A)
None
None
 0.52A 4o2bC-3ds8A:
4.2		 4o2bC-3ds8A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		4 / 6 ILE A 249
GLY A 205
ILE A 162
LEU A 251
 None
 0.76A 4o8fB-3ds8A:
undetectable		 4o8fB-3ds8A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		3 / 3 VAL A 174
ALA A 209
PHE A 238
 None
 0.92A 4olbA-3ds8A:
3.5		 4olbA-3ds8A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		3 / 3 VAL A 174
ALA A 209
PHE A 238
 None
 0.94A 4w5nA-3ds8A:
2.3		 4w5nA-3ds8A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		3 / 3 SER A 102
ALA A 129
VAL A 128
 SO4  A 255 (-2.2A)
None
None
 0.46A 4x1iA-3ds8A:
4.6		 4x1iA-3ds8A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		4 / 4 LEU A  19
ILE A 130
HIS A 101
VAL A  99
 None
None
SO4  A 256 (-3.8A)
None
 1.28A 4xyzA-3ds8A:
undetectable		 4xyzA-3ds8A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		3 / 3 SER A 102
ALA A 129
VAL A 128
 SO4  A 255 (-2.2A)
None
None
 0.42A 5eypA-3ds8A:
5.0		 5eypA-3ds8A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		4 / 5 SER A 195
SER A  12
GLN A  70
ASP A 136
 None
SO4  A 255 ( 2.6A)
None
None
 1.42A 5fhrB-3ds8A:
2.8		 5fhrB-3ds8A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUQ_A_ACTA1278_0
(NAD(P)H
DEHYDROGENASE
[QUINONE] 1)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		4 / 5 HIS A 101
SER A 102
GLN A 223
ILE A 190
 SO4  A 256 (-3.8A)
SO4  A 255 (-2.2A)
None
None
 1.50A 5fuqA-3ds8A:
2.6
5fuqB-3ds8A:
3.5		 5fuqA-3ds8A:
23.29
5fuqB-3ds8A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		4 / 4 LEU A   8
MET A  96
ILE A 130
LEU A 108
 None
 0.87A 5nfpA-3ds8A:
undetectable		 5nfpA-3ds8A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		4 / 8 ALA A 176
SER A 231
THR A 235
GLY A 131
 None
 1.00A 5v0vA-3ds8A:
undetectable		 5v0vA-3ds8A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 3ds8 LIN2722 PROTEIN
(Listeria
innocua) 		3 / 3 SER A 102
ALA A 129
VAL A 128
 SO4  A 255 (-2.2A)
None
None
 0.49A 5xiwC-3ds8A:
3.5		 5xiwC-3ds8A:
15.75