SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dsb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3dsb PUTATIVE
ACETYLTRANSFERASE
(Clostridioides
difficile) 		3 / 3 TYR A 153
MET A 152
ILE A 119
 None
 0.86A 4c8bB-3dsbA:
undetectable		 4c8bB-3dsbA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3dsb PUTATIVE
ACETYLTRANSFERASE
(Clostridioides
difficile) 		4 / 6 ALA A  22
ILE A 119
ILE A  30
VAL A 100
 None
 0.81A 4r21A-3dsbA:
undetectable		 4r21A-3dsbA:
14.14