SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dsf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J9C_C_ACTC1120_0 (HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059)	3dsf	FAB FRAGMENT OF ANTI-OSTEOPONTIN ANTIBODY 23C3, HEAVY CHAIN (Mus musculus)	3 / 3	LYS H 211 TYR H 125 PRO H 126	None	1.49A	2j9cC-3dsfH: undetectable	2j9cC-3dsfH: 19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OF4_B_ACTB313_0 (NITROREDUCTASE)	3dsf	FAB FRAGMENT OF ANTI-OSTEOPONTIN ANTIBODY 23C3, HEAVY CHAIN (Mus musculus)	3 / 3	ALA H 171 VAL H 172 GLN H 174	None	0.74A	3of4B-3dsfH: undetectable	3of4B-3dsfH: 23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM2_A_SALA501_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	3dsf	FAB FRAGMENT OF ANTI-OSTEOPONTIN ANTIBODY 23C3, HEAVY CHAIN (Mus musculus)	4 / 5	TYR H 96 LEU H 83 LEU H 88 ARG H 69	None	1.23A	4em2A-3dsfH: undetectable	4em2A-3dsfH: 18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B58_A_ACTA606_0 (FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT)	3dsf	FAB FRAGMENT OF ANTI-OSTEOPONTIN ANTIBODY 23C3, HEAVY CHAIN (Mus musculus)	4 / 5	GLU H 151 PHE H 149 HIS H 202 THR H 113	None	1.12A	6b58A-3dsfH: undetectable	6b58A-3dsfH: 16.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2J9C_C_ACTC1120_0","HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059","3dsf","FAB FRAGMENT OF ANTI-OSTEOPONTIN ANTIBODY 23C3, HEAVY CHAIN","Mus musculus",3,"LYS H 211;TYR H 125;PRO H 126","None","1.49A","2j9cC-3dsfH:undetectable","2j9cC-3dsfH:19.47"],["3OF4_B_ACTB313_0","NITROREDUCTASE","3dsf","FAB FRAGMENT OF ANTI-OSTEOPONTIN ANTIBODY 23C3, HEAVY CHAIN","Mus musculus",3,"ALA H 171;VAL H 172;GLN H 174","None","0.74A","3of4B-3dsfH:undetectable","3of4B-3dsfH:23.37"],["4EM2_A_SALA501_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349","3dsf","FAB FRAGMENT OF ANTI-OSTEOPONTIN ANTIBODY 23C3, HEAVY CHAIN","Mus musculus",4,"TYR H  96;LEU H  83;LEU H  88;ARG H  69","None","1.23A","4em2A-3dsfH:undetectable","4em2A-3dsfH:18.83"],["6B58_A_ACTA606_0","FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT","3dsf","FAB FRAGMENT OF ANTI-OSTEOPONTIN ANTIBODY 23C3, HEAVY CHAIN","Mus musculus",4,"GLU H 151;PHE H 149;HIS H 202;THR H 113","None","1.12A","6b58A-3dsfH:undetectable","6b58A-3dsfH:16.70"]]