SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dsh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3dsh INTERFERON
REGULATORY FACTOR 5
(Homo
sapiens) 		4 / 5 PHE A 387
PHE A 389
PHE A 289
VAL A 408
 None
 1.23A 2lh6A-3dshA:
undetectable		 2lh6A-3dshA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 3dsh INTERFERON
REGULATORY FACTOR 5
(Homo
sapiens) 		4 / 5 PHE A 420
PHE A 372
LEU A 417
LEU A 424
 None
 1.00A 5veuH-3dshA:
undetectable		 5veuH-3dshA:
19.87