SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dsl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 7 VAL A 129
ILE A 128
HIS A  95
LEU A  89
 None
 0.77A 1j96B-3dslA:
undetectable		 1j96B-3dslA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 5 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.35A 1os2A-3dslA:
9.8		 1os2A-3dslA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 4 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.32A 1os2D-3dslA:
9.8		 1os2D-3dslA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		5 / 10 THR A 110
HIS A 145
GLU A 146
HIS A 149
HIS A 155
 FLE  A 504 (-4.0A)
ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.49A 1r55A-3dslA:
31.4		 1r55A-3dslA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 4 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.29A 1uttA-3dslA:
10.2		 1uttA-3dslA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 4 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.35A 1utzA-3dslA:
10.0		 1utzA-3dslA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 4 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.32A 1utzB-3dslA:
10.1		 1utzB-3dslA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 6 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.33A 1y93A-3dslA:
10.2		 1y93A-3dslA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 4 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.28A 2hu6A-3dslA:
10.0		 2hu6A-3dslA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 8 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.26A 2jihB-3dslA:
25.6		 2jihB-3dslA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 6 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.40A 2ow9A-3dslA:
9.7		 2ow9A-3dslA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 4 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.39A 2ow9B-3dslA:
9.7		 2ow9B-3dslA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 4 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.39A 2ozrC-3dslA:
9.4		 2ozrC-3dslA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 4 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.42A 2ozrD-3dslA:
9.5		 2ozrD-3dslA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 4 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.35A 2ozrE-3dslA:
9.6		 2ozrE-3dslA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		3 / 3 HIS A 145
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.29A 2ozrF-3dslA:
9.4		 2ozrF-3dslA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WB9_A_CYSA301_0
(GLUTATHIONE
TRANSFERASE SIGMA
CLASS)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 5 TYR A 371
GLY A 348
ARG A 369
TYR A 346
 None
 1.32A 2wb9A-3dslA:
0.0		 2wb9A-3dslA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 5 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.35A 3kecA-3dslA:
9.6		 3kecA-3dslA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 5 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.32A 3likA-3dslA:
10.1		 3likA-3dslA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 4 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.31A 3lilA-3dslA:
10.2		 3lilA-3dslA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		5 / 5 ILE A 111
HIS A 145
GLU A 146
HIS A 149
HIS A 155
 FLE  A 504 (-3.9A)
ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 1.27A 3ljgA-3dslA:
10.2		 3ljgA-3dslA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 5 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.33A 3lkaA-3dslA:
10.1		 3lkaA-3dslA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 5 PHE A 181
ILE A 187
MET A  52
ASN A  44
 None
 1.28A 3octA-3dslA:
undetectable		 3octA-3dslA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		5 / 12 LEU A 151
ASN A 150
MET A 119
ALA A  54
ILE A 201
 None
 1.12A 3ut5D-3dslA:
undetectable		 3ut5D-3dslA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 6 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.49A 4a7bA-3dslA:
9.4		 4a7bA-3dslA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		5 / 12 HIS A 155
HIS A 145
ILE A 116
ALA A 114
ILE A 153
 ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
None
None
None
 1.25A 4rp8C-3dslA:
undetectable		 4rp8C-3dslA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		5 / 12 GLY A 170
ASP A 156
ILE A 168
ALA A 144
HIS A 149
 TRP  A 505 (-4.8A)
None
None
None
ZN  A 503 ( 3.3A)
 1.37A 4wh5A-3dslA:
undetectable		 4wh5A-3dslA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		6 / 12 LEU A  50
LEU A 151
ASN A 150
MET A 119
ALA A  54
ILE A 201
 None
 1.15A 4x1iD-3dslA:
undetectable		 4x1iD-3dslA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		5 / 12 LEU A  50
LEU A 151
ASN A 150
MET A 119
ILE A 201
 None
 1.01A 4x1yB-3dslA:
undetectable		 4x1yB-3dslA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		6 / 12 LEU A  50
LEU A 151
ASN A 150
MET A 119
ALA A  54
ILE A 201
 None
 1.14A 4x1yD-3dslA:
undetectable		 4x1yD-3dslA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		5 / 11 LEU A  50
LEU A 151
ASN A 150
MET A 119
ILE A 201
 None
 1.05A 4x20D-3dslA:
undetectable		 4x20D-3dslA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 7 VAL A 129
ILE A 128
HIS A  95
LEU A  89
 None
 0.97A 4xo7A-3dslA:
undetectable		 4xo7A-3dslA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		5 / 12 VAL A 126
GLY A 148
TYR A 115
SER A 118
ILE A 168
 None
 1.43A 4xueB-3dslA:
undetectable		 4xueB-3dslA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 4 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.31A 5n5jA-3dslA:
10.1		 5n5jA-3dslA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 5 HIS A 145
GLU A 146
HIS A 149
HIS A 155
 ZN  A 503 ( 3.3A)
TRP  A 505 (-2.4A)
ZN  A 503 ( 3.3A)
ZN  A 503 ( 3.3A)
 0.33A 5n5kA-3dslA:
10.1		 5n5kA-3dslA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 5 PRO A 399
GLY A 400
THR A 401
LYS A 402
 None
 1.04A 5x23A-3dslA:
undetectable		 5x23A-3dslA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 6 PRO A 399
GLY A 400
THR A 401
LYS A 402
 None
 0.92A 5x24A-3dslA:
undetectable		 5x24A-3dslA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 6 PRO A 399
GLY A 400
THR A 401
LYS A 402
 None
 0.99A 5xxiA-3dslA:
undetectable		 5xxiA-3dslA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 3dsl ZINC
METALLOPROTEINASE-DI
SINTEGRIN
BOTHROPASIN
(Bothrops
jararaca) 		4 / 4 HIS A  95
VAL A  16
LEU A  89
ALA A  98
 None
 1.44A 6d8pB-3dslA:
4.6		 6d8pB-3dslA:
19.20