SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dsm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		3 / 3 VAL A  64
VAL A  73
TRP A  71
 None
 0.74A 1av2A-3dsmA:
undetectable
1av2B-3dsmA:
undetectable		 1av2A-3dsmA:
6.62
1av2B-3dsmA:
6.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		5 / 12 PHE A 322
LEU A 286
GLY A 329
ALA A 330
LEU A  18
 None
 1.06A 1fe2A-3dsmA:
undetectable		 1fe2A-3dsmA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		5 / 12 PHE A 322
LEU A 286
GLY A 329
ALA A 330
LEU A  18
 None
 1.10A 1igxA-3dsmA:
undetectable		 1igxA-3dsmA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		3 / 3 GLU A 225
GLU A 230
LEU A 182
 None
 0.69A 1v8bA-3dsmA:
undetectable		 1v8bA-3dsmA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		4 / 7 ILE A 202
LEU A 253
ASN A 257
ILE A 256
 None
 0.96A 1yc2E-3dsmA:
undetectable		 1yc2E-3dsmA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		5 / 12 ASN A 160
GLU A 243
TYR A 102
GLU A 148
ARG A 101
 None
 1.27A 2f0zA-3dsmA:
6.0		 2f0zA-3dsmA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		3 / 3 VAL A  73
TRP A  71
VAL A  64
 None
 0.75A 2izqC-3dsmA:
undetectable
2izqD-3dsmA:
undetectable		 2izqC-3dsmA:
6.62
2izqD-3dsmA:
6.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		4 / 7 GLN A 305
TYR A 303
TYR A 283
ILE A 256
 None
 1.33A 2ph9A-3dsmA:
undetectable
2ph9B-3dsmA:
undetectable		 2ph9A-3dsmA:
22.35
2ph9B-3dsmA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		3 / 3 ASN A 166
ARG A 167
ASP A 141
 None
 0.89A 2qe6A-3dsmA:
undetectable		 2qe6A-3dsmA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		3 / 3 ASN A 166
ARG A 167
ASP A 141
 None
 0.92A 2qe6B-3dsmA:
undetectable		 2qe6B-3dsmA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		3 / 3 ASP A 204
THR A  21
GLU A 243
 None
 0.79A 2zifB-3dsmA:
undetectable		 2zifB-3dsmA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		3 / 3 SER A  99
GLN A 115
PHE A  97
 None
 0.67A 3g4lC-3dsmA:
undetectable		 3g4lC-3dsmA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		5 / 12 PHE A 105
GLY A  70
ALA A  82
ILE A 124
ILE A 123
 None
 1.40A 3ld6A-3dsmA:
undetectable		 3ld6A-3dsmA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		3 / 3 TYR A 312
TYR A 283
GLU A 321
 None
 0.97A 3pfgA-3dsmA:
2.3		 3pfgA-3dsmA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		4 / 4 VAL A  47
PHE A  19
PHE A 331
VAL A 309
 None
 0.80A 3rv5C-3dsmA:
undetectable
3rv5D-3dsmA:
undetectable		 3rv5C-3dsmA:
14.24
3rv5D-3dsmA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		4 / 6 GLY A  57
TYR A  49
ALA A  31
GLU A  46
 None
 0.99A 4ae1A-3dsmA:
undetectable		 4ae1A-3dsmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		5 / 12 PHE A 227
ILE A 135
TYR A 112
ARG A 167
LEU A 169
 None
 1.36A 4kotA-3dsmA:
undetectable		 4kotA-3dsmA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		4 / 8 ASP A  67
ILE A  69
ASP A  84
ILE A  85
 None
 0.95A 4ndnD-3dsmA:
undetectable		 4ndnD-3dsmA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		4 / 4 CYH A 332
PHE A  19
ILE A  80
GLY A  70
 None
 1.49A 5hesB-3dsmA:
undetectable		 5hesB-3dsmA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		4 / 6 ASP A 302
ARG A 279
TYR A 310
TYR A 323
 None
 1.11A 5igyA-3dsmA:
2.8		 5igyA-3dsmA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_B_SAMB503_0
(CARNOSINE
N-METHYLTRANSFERASE)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		5 / 12 ASN A 160
TRP A 162
SER A 163
PHE A 122
TYR A 102
 None
 1.48A 5yf0B-3dsmA:
0.0		 5yf0B-3dsmA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		3 / 3 GLU A 215
ASP A 204
PRO A 241
 None
 0.63A 6berA-3dsmA:
undetectable		 6berA-3dsmA:
5.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		4 / 6 ASP A 194
GLU A 230
ASP A 223
GLU A 225
 None
 1.47A 6mn5A-3dsmA:
undetectable		 6mn5A-3dsmA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		4 / 6 ASP A 194
GLU A 230
ASP A 223
GLU A 225
 None
 1.48A 6mn5C-3dsmA:
undetectable		 6mn5C-3dsmA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_D_LLLD301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3dsm UNCHARACTERIZED
PROTEIN BACUNI_02894
(Bacteroides
uniformis) 		4 / 6 ASP A 194
GLU A 230
ASP A 223
GLU A 225
 None
 1.40A 6mn5D-3dsmA:
undetectable		 6mn5D-3dsmA:
12.34