SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dt8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 9 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.30A 1c9sA-3dt8A:
undetectable
1c9sB-3dt8A:
undetectable
1c9sA-3dt8A:
15.02
1c9sB-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.25A 1c9sB-3dt8A:
undetectable
1c9sC-3dt8A:
undetectable
1c9sB-3dt8A:
15.02
1c9sC-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.27A 1c9sG-3dt8A:
undetectable
1c9sH-3dt8A:
undetectable
1c9sG-3dt8A:
15.02
1c9sH-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
3 / 3 GLN A  78
HIS A  79
PRO A  13
None
0.90A 1d8cA-3dt8A:
undetectable
1d8cA-3dt8A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
4 / 8 ILE A  96
HIS A 209
LEU A 208
VAL A  98
None
0.86A 1fslA-3dt8A:
undetectable
1fslA-3dt8A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
4 / 8 ILE A  96
HIS A 209
LEU A 208
VAL A  98
None
0.87A 1fslB-3dt8A:
undetectable
1fslB-3dt8A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.29A 1gtfC-3dt8A:
undetectable
1gtfD-3dt8A:
undetectable
1gtfC-3dt8A:
15.02
1gtfD-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 9 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.26A 1gtfF-3dt8A:
undetectable
1gtfG-3dt8A:
undetectable
1gtfF-3dt8A:
15.02
1gtfG-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.26A 1gtfG-3dt8A:
undetectable
1gtfH-3dt8A:
undetectable
1gtfG-3dt8A:
15.02
1gtfH-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.28A 1gtfH-3dt8A:
undetectable
1gtfI-3dt8A:
undetectable
1gtfH-3dt8A:
15.02
1gtfI-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 11 GLY A 116
HIS A  79
THR A  77
ILE A 117
ARG A  83
None
1.30A 1gtfU-3dt8A:
undetectable
1gtfV-3dt8A:
undetectable
1gtfU-3dt8A:
15.02
1gtfV-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 11 LEU A 194
LEU A 139
ALA A 207
ALA A 174
TYR A 201
SGB  A  47 ( 4.6A)
None
None
None
None
1.40A 1iiuA-3dt8A:
undetectable
1iiuA-3dt8A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 11 LEU A  84
VAL A 101
GLY A  45
LEU A  81
GLU A  88
None
1.50A 1jkhA-3dt8A:
1.2
1jkhB-3dt8A:
undetectable
1jkhA-3dt8A:
16.79
1jkhB-3dt8A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 11 GLY A 116
HIS A  79
THR A  77
ILE A 117
ARG A  83
None
1.28A 1utdM-3dt8A:
undetectable
1utdN-3dt8A:
undetectable
1utdM-3dt8A:
15.02
1utdN-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
4 / 5 VAL A  98
VAL A  97
GLN A 130
ARG A  93
None
1.32A 3bjwH-3dt8A:
undetectable
3bjwH-3dt8A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
4 / 5 VAL A  98
VAL A  97
GLN A 130
ARG A  93
None
1.30A 3bjwB-3dt8A:
undetectable
3bjwB-3dt8A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
3 / 3 HIS A  27
HIS A  28
MET A  24
None
0.83A 3mihA-3dt8A:
undetectable
3mihA-3dt8A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
3 / 3 ARG A  29
ASP A  20
GLN A  18
None
0.92A 4azsA-3dt8A:
3.4
4azsA-3dt8A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
4 / 4 ASN A   6
ALA A   8
GLY A 115
THR A 114
None
1.20A 4bboC-3dt8A:
undetectable
4bboC-3dt8A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 9 LEU A 136
VAL A 121
ILE A 120
LEU A  84
ILE A 117
None
1.11A 4kukA-3dt8A:
undetectable
4kukA-3dt8A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.25A 5eeuD-3dt8A:
undetectable
5eeuE-3dt8A:
undetectable
5eeuD-3dt8A:
15.02
5eeuE-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.25A 5eeuH-3dt8A:
undetectable
5eeuI-3dt8A:
undetectable
5eeuH-3dt8A:
15.02
5eeuI-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.26A 5eeuJ-3dt8A:
undetectable
5eeuK-3dt8A:
undetectable
5eeuJ-3dt8A:
15.02
5eeuK-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.24A 5eevD-3dt8A:
undetectable
5eevE-3dt8A:
undetectable
5eevD-3dt8A:
15.02
5eevE-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.26A 5eevJ-3dt8A:
undetectable
5eevK-3dt8A:
undetectable
5eevJ-3dt8A:
15.02
5eevK-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.24A 5eewD-3dt8A:
undetectable
5eewE-3dt8A:
undetectable
5eewD-3dt8A:
15.02
5eewE-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.25A 5eewH-3dt8A:
undetectable
5eewI-3dt8A:
undetectable
5eewH-3dt8A:
15.02
5eewI-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.26A 5eewJ-3dt8A:
undetectable
5eewK-3dt8A:
undetectable
5eewJ-3dt8A:
15.02
5eewK-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.24A 5eexD-3dt8A:
undetectable
5eexE-3dt8A:
undetectable
5eexD-3dt8A:
15.02
5eexE-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.25A 5eexH-3dt8A:
undetectable
5eexI-3dt8A:
undetectable
5eexH-3dt8A:
15.02
5eexI-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 11 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.29A 5eexI-3dt8A:
undetectable
5eexJ-3dt8A:
undetectable
5eexI-3dt8A:
15.02
5eexJ-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.26A 5eexJ-3dt8A:
undetectable
5eexK-3dt8A:
undetectable
5eexJ-3dt8A:
15.02
5eexK-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.24A 5eeyD-3dt8A:
undetectable
5eeyE-3dt8A:
undetectable
5eeyD-3dt8A:
15.02
5eeyE-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 11 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.29A 5eeyI-3dt8A:
undetectable
5eeyJ-3dt8A:
undetectable
5eeyI-3dt8A:
15.02
5eeyJ-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.26A 5eeyJ-3dt8A:
undetectable
5eeyK-3dt8A:
undetectable
5eeyJ-3dt8A:
15.02
5eeyK-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.24A 5eezD-3dt8A:
undetectable
5eezE-3dt8A:
undetectable
5eezD-3dt8A:
15.02
5eezE-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 11 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.29A 5eezI-3dt8A:
undetectable
5eezJ-3dt8A:
undetectable
5eezI-3dt8A:
15.02
5eezJ-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.24A 5ef0D-3dt8A:
undetectable
5ef0E-3dt8A:
undetectable
5ef0D-3dt8A:
15.02
5ef0E-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 11 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.29A 5ef0I-3dt8A:
undetectable
5ef0J-3dt8A:
undetectable
5ef0I-3dt8A:
15.02
5ef0J-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.24A 5ef1D-3dt8A:
undetectable
5ef1E-3dt8A:
undetectable
5ef1D-3dt8A:
15.02
5ef1E-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 11 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.28A 5ef1I-3dt8A:
undetectable
5ef1J-3dt8A:
undetectable
5ef1I-3dt8A:
15.02
5ef1J-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.24A 5ef2D-3dt8A:
undetectable
5ef2E-3dt8A:
undetectable
5ef2D-3dt8A:
15.02
5ef2E-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 11 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.28A 5ef2I-3dt8A:
undetectable
5ef2J-3dt8A:
undetectable
5ef2I-3dt8A:
15.02
5ef2J-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 10 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.24A 5ef3D-3dt8A:
undetectable
5ef3E-3dt8A:
undetectable
5ef3D-3dt8A:
15.02
5ef3E-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 11 ARG A  83
GLY A 116
HIS A  79
THR A  77
ILE A 117
None
1.28A 5ef3I-3dt8A:
undetectable
5ef3J-3dt8A:
undetectable
5ef3I-3dt8A:
15.02
5ef3J-3dt8A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)
3dt8 BRAIN
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
SUBUNIT ALPHA

(Bos
taurus)
5 / 12 GLY A 137
VAL A  98
VAL A 204
ALA A 207
LEU A 208
None
1.04A 5kocA-3dt8A:
undetectable
5kocA-3dt8A:
19.42