SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dtd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 3dtd INVASION-ASSOCIATED
PROTEIN B
(Bartonella
henselae) 		3 / 3 GLU A  69
LYS A 150
VAL A 168
 None
 0.92A 1l2iA-3dtdA:
undetectable		 1l2iA-3dtdA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 3dtd INVASION-ASSOCIATED
PROTEIN B
(Bartonella
henselae) 		4 / 6 TRP A  50
GLY A  92
PHE A 135
SER A  91
 None
 1.15A 2a3cA-3dtdA:
undetectable		 2a3cA-3dtdA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 3dtd INVASION-ASSOCIATED
PROTEIN B
(Bartonella
henselae) 		4 / 6 TRP A  50
GLY A  92
PHE A 135
SER A  91
 None
 1.17A 2a3cB-3dtdA:
undetectable		 2a3cB-3dtdA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3dtd INVASION-ASSOCIATED
PROTEIN B
(Bartonella
henselae) 		4 / 4 GLU A 160
PRO A 161
ILE A 155
LEU A 101
 None
 1.20A 5m45A-3dtdA:
undetectable		 5m45A-3dtdA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3dtd INVASION-ASSOCIATED
PROTEIN B
(Bartonella
henselae) 		4 / 4 GLU A 160
PRO A 161
ILE A 155
LEU A 101
 None
 1.23A 5m45D-3dtdA:
undetectable		 5m45D-3dtdA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3dtd INVASION-ASSOCIATED
PROTEIN B
(Bartonella
henselae) 		4 / 4 GLU A 160
PRO A 161
ILE A 155
LEU A 101
 None
 1.20A 5m45G-3dtdA:
undetectable		 5m45G-3dtdA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3dtd INVASION-ASSOCIATED
PROTEIN B
(Bartonella
henselae) 		4 / 4 GLU A 160
PRO A 161
ILE A 155
LEU A 101
 None
 1.29A 5m45J-3dtdA:
undetectable		 5m45J-3dtdA:
12.31