SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dte'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA2_0
(ACTINOMYCIN D)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		4 / 4 THR A 193
PRO A 212
THR A 211
PRO A 214
 None
 1.39A 1a7yA-3dteA:
undetectable
1a7yC-3dteA:
undetectable		 1a7yA-3dteA:
18.42
1a7yC-3dteA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		4 / 7 GLU A 113
LYS A  15
LEU A  11
ALA A  14
 None
 1.08A 1sn0B-3dteA:
undetectable
1sn0D-3dteA:
undetectable		 1sn0B-3dteA:
20.87
1sn0D-3dteA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		4 / 4 LEU A  21
SER A  24
TYR A  25
LEU A  88
 None
 1.26A 1xz1A-3dteA:
undetectable		 1xz1A-3dteA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		4 / 4 LEU A  21
SER A  24
TYR A  25
LEU A  88
 None
 1.26A 1xz3A-3dteA:
undetectable		 1xz3A-3dteA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		5 / 11 ASN A 117
VAL A 118
ILE A  84
ALA A  22
ASP A  55
 None
 1.40A 2iyfA-3dteA:
undetectable		 2iyfA-3dteA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		4 / 8 LEU A  99
LEU A  89
ASP A  92
ASP A  94
 None
 1.04A 2j2pA-3dteA:
undetectable
2j2pB-3dteA:
undetectable		 2j2pA-3dteA:
21.85
2j2pB-3dteA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		4 / 6 HIS A 217
ALA A 249
ALA A 222
THR A 225
 None
 1.06A 2xfhA-3dteA:
undetectable		 2xfhA-3dteA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		5 / 11 THR A 166
LEU A 134
GLY A 138
THR A 140
VAL A 170
 None
 1.13A 3lxiB-3dteA:
undetectable		 3lxiB-3dteA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		5 / 12 LEU A 124
ARG A  77
ALA A 151
GLU A  74
ARG A 255
 None
 1.46A 4cpzA-3dteA:
undetectable		 4cpzA-3dteA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		5 / 12 LEU A 124
ARG A  77
ALA A 151
GLU A  74
ARG A 255
 None
 1.46A 4cpzB-3dteA:
undetectable		 4cpzB-3dteA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		4 / 4 TYR A  25
GLY A  31
SER A  36
LEU A  37
 None
 1.39A 5bphC-3dteA:
undetectable		 5bphC-3dteA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		3 / 3 ASP A 216
SER A 233
TYR A 234
 None
 0.84A 5glmA-3dteA:
undetectable		 5glmA-3dteA:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		5 / 10 LEU A 147
ALA A 120
SER A  85
PHE A  78
THR A 156
 None
 1.27A 5mm4B-3dteA:
undetectable		 5mm4B-3dteA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		4 / 8 ILE A  67
ASN A 117
LEU A 123
ALA A 120
 None
 0.77A 5y7pC-3dteA:
undetectable		 5y7pC-3dteA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 3dte IRRE PROTEIN
(Deinococcus
deserti) 		5 / 12 VAL A 194
MET A 243
PRO A 139
THR A 140
GLY A 141
 None
 1.18A 6brdC-3dteA:
undetectable		 6brdC-3dteA:
12.96