SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dtn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 9 ILE A  95
LEU A 128
ARG A 131
GLY A  50
LEU A  47
 None
 0.95A 1e7aB-3dtnA:
undetectable		 1e7aB-3dtnA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 GLY A  52
THR A  53
SER A  75
MET A  78
SER A 116
 None
 0.91A 1nbiC-3dtnA:
15.6		 1nbiC-3dtnA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 GLY A  52
THR A  53
SER A  75
MET A  78
SER A 116
 None
 0.91A 1nbiD-3dtnA:
15.6		 1nbiD-3dtnA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		4 / 8 GLY A 150
THR A 161
ILE A 155
ASN A 157
 None
 0.90A 2a8tB-3dtnA:
undetectable		 2a8tB-3dtnA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 ASP A  48
GLY A  50
GLY A  52
LEU A  56
LEU A 120
 None
 0.71A 2nxeA-3dtnA:
14.8		 2nxeA-3dtnA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		6 / 12 ASP A  48
LEU A  49
GLY A  50
GLY A  52
LEU A  56
LEU A 128
 None
 1.46A 2nxeA-3dtnA:
14.8		 2nxeA-3dtnA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 ASP A  48
GLY A  50
GLY A  52
LEU A  56
LEU A 120
 None
 0.74A 2nxeB-3dtnA:
15.1		 2nxeB-3dtnA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 ASP A  48
LEU A  49
GLY A  50
GLY A  52
LEU A  56
 None
 0.89A 2nxeB-3dtnA:
15.1		 2nxeB-3dtnA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 ASP A  48
GLY A  50
LEU A  56
ASP A  73
LEU A 120
 None
 0.73A 3cjtC-3dtnA:
15.3		 3cjtC-3dtnA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 ASP A  48
LEU A  49
GLY A  50
LEU A  56
ASP A  73
 None
 0.90A 3cjtC-3dtnA:
15.3		 3cjtC-3dtnA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 TYR A  30
GLY A  50
GLY A  52
ASP A  98
SER A 116
 None
 1.10A 3dlcA-3dtnA:
15.6		 3dlcA-3dtnA:
27.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 TYR A  30
GLY A  50
GLY A  52
SER A  75
SER A 116
 None
 0.84A 3dlcA-3dtnA:
15.6		 3dlcA-3dtnA:
27.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 VAL A 207
LEU A 147
ILE A 117
TYR A 129
GLN A 195
 None
 1.36A 3elzC-3dtnA:
undetectable		 3elzC-3dtnA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 GLY A  52
SER A  75
MET A  78
ASP A  98
ALA A 114
 None
 0.89A 3ou6A-3dtnA:
17.7		 3ou6A-3dtnA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 GLY A  52
SER A  75
MET A  78
ALA A 114
HIS A 119
 None
 0.61A 3ou6B-3dtnA:
17.6		 3ou6B-3dtnA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 GLY A  52
SER A  75
MET A  78
ALA A 114
HIS A 119
 None
 0.64A 3ou7B-3dtnA:
17.7		 3ou7B-3dtnA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		3 / 3 GLY A  52
ASP A  73
ASP A  98
 None
 0.42A 3ou7C-3dtnA:
17.5		 3ou7C-3dtnA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 GLY A  52
SER A  75
MET A  78
ASP A  98
HIS A 119
 None
 0.68A 3pfgA-3dtnA:
17.5		 3pfgA-3dtnA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 GLY A  52
SER A  75
MET A  78
SER A 116
HIS A 119
 None
 1.00A 3pfgA-3dtnA:
17.5		 3pfgA-3dtnA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 GLY A  50
GLY A  52
THR A  53
LEU A  55
ASP A  98
 None
 0.45A 3sglA-3dtnA:
6.4		 3sglA-3dtnA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		4 / 4 SER A  33
ASP A  48
ASP A  73
ALA A 114
 None
 1.22A 3uj6A-3dtnA:
18.8		 3uj6A-3dtnA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		7 / 12 GLY A  50
GLY A  52
ASP A  73
MET A  78
ASP A  98
HIS A 119
LEU A 120
 None
 0.75A 4iv8A-3dtnA:
19.2		 4iv8A-3dtnA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		7 / 12 GLY A  50
GLY A  52
ASP A  73
MET A  78
ASP A  98
HIS A 119
LEU A 120
 None
 0.77A 4iv8B-3dtnA:
19.3		 4iv8B-3dtnA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 GLY A  50
GLY A  52
SER A 116
HIS A 119
LEU A 120
 None
 0.82A 4mwzA-3dtnA:
19.0		 4mwzA-3dtnA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 GLY A  50
GLY A  52
SER A  75
MET A  78
HIS A 119
 None
 0.62A 4qdjA-3dtnA:
17.2		 4qdjA-3dtnA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		3 / 3 ASP A 187
HIS A 118
LYS A 188
 None
 0.88A 4qzuD-3dtnA:
undetectable		 4qzuD-3dtnA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_1
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		4 / 4 ASP A  48
GLY A  52
ASP A  73
ASP A  98
 None
 0.53A 5e72A-3dtnA:
15.5		 5e72A-3dtnA:
26.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 GLY A  52
SER A  75
MET A  78
HIS A 119
LEU A 120
 None
 0.95A 5gwxA-3dtnA:
16.9		 5gwxA-3dtnA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 GLY A  52
SER A  75
MET A  78
SER A 116
HIS A 119
 None
 0.84A 5gwxA-3dtnA:
16.9		 5gwxA-3dtnA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 GLY A  52
SER A  75
MET A  78
SER A 116
HIS A 119
 None
 0.77A 5hikA-3dtnA:
17.4		 5hikA-3dtnA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		5 / 12 GLY A  50
GLY A  52
ASP A  73
HIS A 119
LEU A 120
 None
 0.42A 5wy0A-3dtnA:
14.3		 5wy0A-3dtnA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3dtn PUTATIVE
METHYLTRANSFERASE
MM_2633
(Methanosarcina
mazei) 		6 / 12 GLY A  52
GLY A  54
ILE A 117
VAL A 112
LEU A  49
GLY A  50
 None
 1.15A 5zhmB-3dtnA:
undetectable		 5zhmB-3dtnA:
22.07