SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dto'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		5 / 9 ALA A  54
ILE A 100
ILE A  30
ILE A  61
ILE A  97
 None
 0.96A 1hshB-3dtoA:
undetectable		 1hshB-3dtoA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		4 / 7 LYS A  38
LEU A  35
GLU A  42
ALA A  37
 None
 1.11A 1sn0B-3dtoA:
undetectable
1sn0D-3dtoA:
undetectable		 1sn0B-3dtoA:
20.18
1sn0D-3dtoA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		4 / 6 LYS A  38
LEU A  35
GLU A  42
ALA A  37
 None
 1.12A 1sn5A-3dtoA:
undetectable		 1sn5A-3dtoA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		5 / 12 LEU A 180
ASP A 125
VAL A  33
HIS A  29
ALA A 115
 None
 1.14A 2g70A-3dtoA:
undetectable		 2g70A-3dtoA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		5 / 12 LEU A 180
ASP A 125
VAL A  33
HIS A  29
ALA A 115
 None
 1.13A 2g70B-3dtoA:
undetectable		 2g70B-3dtoA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		5 / 12 LEU A 180
ASP A 125
VAL A  33
HIS A  29
ALA A 115
 None
 1.15A 2g72A-3dtoA:
undetectable		 2g72A-3dtoA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		5 / 12 ALA A  10
LEU A   7
LEU A  56
ILE A  61
LEU A  76
 None
 1.10A 2qxsB-3dtoA:
undetectable		 2qxsB-3dtoA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		5 / 12 PHE A  57
THR A  93
ILE A  96
ILE A 100
ASN A  98
 None
 1.13A 2rlcA-3dtoA:
undetectable		 2rlcA-3dtoA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		4 / 5 VAL A 118
VAL A 117
THR A  99
THR A  34
 None
 0.85A 3bjwA-3dtoA:
undetectable		 3bjwA-3dtoA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		4 / 5 VAL A 118
VAL A 117
THR A  99
THR A  34
 None
 0.86A 3bjwG-3dtoA:
undetectable		 3bjwG-3dtoA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		4 / 5 VAL A 118
VAL A 117
THR A  99
THR A  34
 None
 0.81A 3bjwC-3dtoA:
undetectable		 3bjwC-3dtoA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		4 / 5 VAL A 118
VAL A 117
THR A  99
THR A  34
 None
 0.86A 3bjwD-3dtoA:
undetectable		 3bjwD-3dtoA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		5 / 9 ALA A  54
ILE A 100
ILE A  30
ILE A  61
ILE A  97
 None
 1.04A 3s45A-3dtoA:
undetectable		 3s45A-3dtoA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		5 / 11 ALA A  54
ILE A 100
ILE A  30
ILE A  61
ILE A  97
 None
 0.84A 3s45B-3dtoA:
undetectable		 3s45B-3dtoA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		3 / 3 LYS A 181
ASP A 182
ARG A 123
 None
 0.79A 5jwaA-3dtoA:
undetectable
5jwaH-3dtoA:
undetectable		 5jwaA-3dtoA:
18.61
5jwaH-3dtoA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		3 / 3 HIS A  29
ASP A  59
HIS A  58
 None
 0.58A 5oexA-3dtoA:
undetectable		 5oexA-3dtoA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		3 / 3 HIS A  29
ASP A  59
HIS A  58
 None
 0.56A 5oexB-3dtoA:
undetectable		 5oexB-3dtoA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		3 / 3 HIS A  29
ASP A  59
HIS A  58
 None
 0.60A 5oexC-3dtoA:
undetectable		 5oexC-3dtoA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		3 / 3 HIS A  29
ASP A  59
HIS A  58
 None
 0.60A 5oexD-3dtoA:
undetectable		 5oexD-3dtoA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		5 / 12 ALA A  10
LEU A  76
ILE A  77
VAL A  85
ASP A  95
 None
 1.29A 5vlmG-3dtoA:
undetectable		 5vlmG-3dtoA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 3dto BH2835 PROTEIN
(Bacillus
halodurans) 		3 / 3 ARG A 196
PHE A 199
GLY A 128
 None
 0.70A 6fgdA-3dtoA:
undetectable		 6fgdA-3dtoA:
18.75