SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dtt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 3dtt NADP OXIDOREDUCTASE
(Arthrobacter
sp.
FB24) 		4 / 7 ALA A  72
GLU A  73
LEU A  74
VAL A  76
 None
 0.93A 1hk2A-3dttA:
undetectable		 1hk2A-3dttA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 3dtt NADP OXIDOREDUCTASE
(Arthrobacter
sp.
FB24) 		4 / 8 PRO A 107
GLU A 128
ALA A 198
PRO A 120
 None
 0.88A 2v32A-3dttA:
undetectable
2v32B-3dttA:
undetectable		 2v32A-3dttA:
22.51
2v32B-3dttA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3dtt NADP OXIDOREDUCTASE
(Arthrobacter
sp.
FB24) 		4 / 8 PRO A 120
PRO A 107
GLU A 128
ALA A 198
 None
 0.88A 2v32A-3dttA:
undetectable
2v32B-3dttA:
undetectable		 2v32A-3dttA:
22.51
2v32B-3dttA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3dtt NADP OXIDOREDUCTASE
(Arthrobacter
sp.
FB24) 		4 / 7 VAL A  26
GLY A  17
ALA A  18
LEU A  22
 None
 0.87A 2wekB-3dttA:
5.2		 2wekB-3dttA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3dtt NADP OXIDOREDUCTASE
(Arthrobacter
sp.
FB24) 		4 / 7 LEU A 126
VAL A 139
LEU A  88
LEU A  19
 None
 0.87A 3g8iA-3dttA:
undetectable		 3g8iA-3dttA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3dtt NADP OXIDOREDUCTASE
(Arthrobacter
sp.
FB24) 		4 / 4 LEU A  74
MET A 151
ILE A 195
ASP A 191
 None
 1.18A 3hecA-3dttA:
undetectable		 3hecA-3dttA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3dtt NADP OXIDOREDUCTASE
(Arthrobacter
sp.
FB24) 		5 / 12 ILE A  28
GLY A  29
ALA A  87
PRO A  33
ALA A  69
 None
None
NAP  A 300 ( 3.8A)
None
None
 1.10A 3jb1A-3dttA:
undetectable		 3jb1A-3dttA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3dtt NADP OXIDOREDUCTASE
(Arthrobacter
sp.
FB24) 		5 / 12 GLY A  29
ALA A  87
PRO A  33
ALA A  69
VAL A  68
 None
NAP  A 300 ( 3.8A)
None
None
None
 0.97A 3jb3A-3dttA:
undetectable		 3jb3A-3dttA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 3dtt NADP OXIDOREDUCTASE
(Arthrobacter
sp.
FB24) 		5 / 9 THR A 142
LEU A 184
LEU A 181
VAL A  76
VAL A 102
 None
 1.01A 4c9kB-3dttA:
undetectable		 4c9kB-3dttA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_B_010B607_0
(HNL ISOENZYME 5)		 3dtt NADP OXIDOREDUCTASE
(Arthrobacter
sp.
FB24) 		5 / 10 ALA A  18
ALA A  16
VAL A   5
LEU A 180
VAL A  76
 None
 1.17A 5eb5B-3dttA:
undetectable		 5eb5B-3dttA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3dtt NADP OXIDOREDUCTASE
(Arthrobacter
sp.
FB24) 		4 / 6 LEU A  37
SER A  51
PHE A  50
HIS A  57
 None
 1.18A 5om3A-3dttA:
undetectable
5om3B-3dttA:
undetectable		 5om3A-3dttA:
18.22
5om3B-3dttA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3dtt NADP OXIDOREDUCTASE
(Arthrobacter
sp.
FB24) 		5 / 10 VAL A  75
ALA A   4
LEU A  96
THR A  27
LEU A  88
 None
 0.91A 6f5uA-3dttA:
undetectable
6f5uB-3dttA:
undetectable		 6f5uA-3dttA:
15.49
6f5uB-3dttA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_B_FFOB403_0
(THYMIDYLATE SYNTHASE)		 3dtt NADP OXIDOREDUCTASE
(Arthrobacter
sp.
FB24) 		5 / 10 ILE A  85
LEU A  96
ASP A 103
LEU A 126
GLY A 127
 None
 1.41A 6r2eB-3dttA:
undetectable		 6r2eB-3dttA:
21.68