SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3duz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 3duz MAJOR ENVELOPE
GLYCOPROTEIN
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 LYS A  49
LEU A  47
ALA A 227
LEU A 229
 None
 0.84A 1eta2-3duzA:
undetectable		 1eta2-3duzA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 3duz MAJOR ENVELOPE
GLYCOPROTEIN
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 6 LYS A  49
LEU A  47
ALA A 227
LEU A 229
 None
 0.81A 1ictB-3duzA:
undetectable		 1ictB-3duzA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 3duz MAJOR ENVELOPE
GLYCOPROTEIN
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 9 LEU A 102
GLY A 438
ILE A 442
ILE A 212
ILE A  65
 None
 0.95A 3s56B-3duzA:
undetectable		 3s56B-3duzA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 3duz MAJOR ENVELOPE
GLYCOPROTEIN
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 7 LYS A  49
LEU A  47
ALA A 227
LEU A 229
 None
 0.80A 4d7bA-3duzA:
undetectable		 4d7bA-3duzA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 3duz MAJOR ENVELOPE
GLYCOPROTEIN
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		3 / 3 LYS A  49
LEU A  47
ALA A 227
 None
 0.59A 4iizA-3duzA:
undetectable		 4iizA-3duzA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 3duz MAJOR ENVELOPE
GLYCOPROTEIN
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 8 LYS A  49
LEU A  47
ALA A 227
LEU A 229
 None
 0.79A 4iizB-3duzA:
undetectable		 4iizB-3duzA:
14.23