SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dv8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 3dv8 TRANSCRIPTIONAL
REGULATOR, CRP/FNR
FAMILY
([Eubacterium]
rectale) 		5 / 12 LEU A 155
LEU A 156
GLN A 217
THR A 173
ILE A 169
 None
 1.50A 1p93A-3dv8A:
undetectable		 1p93A-3dv8A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 3dv8 TRANSCRIPTIONAL
REGULATOR, CRP/FNR
FAMILY
([Eubacterium]
rectale) 		4 / 6 LEU A 167
PHE A  72
ASP A  73
GLU A 162
 None
 1.14A 2vn1B-3dv8A:
undetectable		 2vn1B-3dv8A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3dv8 TRANSCRIPTIONAL
REGULATOR, CRP/FNR
FAMILY
([Eubacterium]
rectale) 		4 / 7 ILE A  35
GLU A  95
TYR A  57
VAL A 135
 None
 1.04A 4a97H-3dv8A:
undetectable		 4a97H-3dv8A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 3dv8 TRANSCRIPTIONAL
REGULATOR, CRP/FNR
FAMILY
([Eubacterium]
rectale) 		3 / 3 ARG A  70
ASP A  73
ASP A 101
 None
 0.86A 4kicB-3dv8A:
2.9		 4kicB-3dv8A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3dv8 TRANSCRIPTIONAL
REGULATOR, CRP/FNR
FAMILY
([Eubacterium]
rectale) 		4 / 7 GLY A  33
GLU A  95
ASN A 176
THR A 173
 None
 0.80A 5ybbB-3dv8A:
undetectable		 5ybbB-3dv8A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 3dv8 TRANSCRIPTIONAL
REGULATOR, CRP/FNR
FAMILY
([Eubacterium]
rectale) 		5 / 9 LEU A 200
VAL A 198
PHE A 154
SER A 153
ILE A 207
 None
 1.05A 6fdyU-3dv8A:
undetectable		 6fdyU-3dv8A:
19.86