SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		3 / 3 GLY A  29
GLU A  62
ASP A  33
 MG  A 301 ( 4.6A)
MG  A 301 ( 3.1A)
None
 0.68A 2b25B-3dv9A:
2.3		 2b25B-3dv9A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		4 / 7 TYR A  59
GLY A  29
ASN A 187
ASP A 229
 EDO  A 303 (-4.8A)
MG  A 301 ( 4.6A)
MG  A 301 (-2.7A)
None
 1.08A 2g72B-3dv9A:
2.1		 2g72B-3dv9A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		3 / 3 ARG A  64
GLN A 193
PRO A 163
 None
 0.95A 2qhfA-3dv9A:
undetectable		 2qhfA-3dv9A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		4 / 7 ILE A 117
TRP A 234
PHE A 230
GLU A 112
 None
 1.46A 3e7gA-3dv9A:
undetectable
3e7gB-3dv9A:
1.5		 3e7gA-3dv9A:
19.91
3e7gB-3dv9A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		4 / 7 MET A  46
ILE A  90
TYR A  91
ILE A  87
 None
 1.02A 3hgxA-3dv9A:
undetectable		 3hgxA-3dv9A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF201_1
(PROTEIN S100-A4)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		4 / 5 MET A  27
PHE A  25
PHE A 147
PHE A 143
 None
 1.25A 3ko0F-3dv9A:
undetectable
3ko0G-3dv9A:
undetectable		 3ko0F-3dv9A:
16.94
3ko0G-3dv9A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		5 / 12 LEU A 183
MET A 125
LEU A 122
GLY A 175
LEU A 172
 None
 1.12A 3olsA-3dv9A:
undetectable		 3olsA-3dv9A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		5 / 9 ILE A   6
PHE A   2
ALA A 220
LEU A 237
ALA A 240
 None
 0.92A 3ozvB-3dv9A:
4.7		 3ozvB-3dv9A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		4 / 7 TRP A 234
PHE A 230
GLU A 112
ILE A 117
 None
 1.45A 4cx7C-3dv9A:
undetectable
4cx7D-3dv9A:
undetectable		 4cx7C-3dv9A:
20.00
4cx7D-3dv9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		5 / 12 PHE A 230
PHE A  25
LEU A 222
LEU A 237
ILE A  18
 None
 1.13A 4g1bD-3dv9A:
5.1		 4g1bD-3dv9A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		5 / 12 LEU A 183
MET A 125
LEU A 122
GLY A 175
LEU A 172
 None
 1.15A 4j26A-3dv9A:
undetectable		 4j26A-3dv9A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		5 / 12 PHE A  25
GLU A 186
ALA A 182
ALA A 198
GLY A 199
 None
MG  A 301 ( 4.6A)
None
None
None
 1.08A 4oaeA-3dv9A:
undetectable		 4oaeA-3dv9A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		4 / 8 PHE A 201
LEU A 241
LEU A 222
PHE A 224
 None
 0.69A 4qopC-3dv9A:
undetectable		 4qopC-3dv9A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_B_SALB504_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		4 / 6 SER A 130
HIS A  38
PHE A  98
MET A  27
 None
 1.50A 5u6nB-3dv9A:
5.0		 5u6nB-3dv9A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		4 / 4 ILE A  45
LEU A  53
HIS A  38
ALA A  58
 None
 1.03A 6ck2C-3dv9A:
undetectable
6ck2D-3dv9A:
undetectable		 6ck2C-3dv9A:
8.38
6ck2D-3dv9A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		4 / 7 GLY A 199
ALA A 198
VAL A 127
LEU A  24
 None
 0.79A 6dwnB-3dv9A:
undetectable		 6dwnB-3dv9A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 3dv9 BETA-PHOSPHOGLUCOMUT
ASE
(Bacteroides
vulgatus) 		5 / 12 GLY A  63
HIS A  61
TYR A  59
PRO A 189
GLY A 191
 PO4  A 302 (-3.6A)
None
EDO  A 303 (-4.8A)
None
None
 1.29A 6gngA-3dv9A:
6.0		 6gngA-3dv9A:
17.69