SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dwm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3dwm 9.5 KDA CULTURE
FILTRATE ANTIGEN
CFP10A
(Mycobacterium
tuberculosis) 		4 / 5 THR A  76
LEU A  28
VAL A  31
LEU A  35
 None
 0.54A 1fbmE-3dwmA:
undetectable		 1fbmE-3dwmA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 3dwm 9.5 KDA CULTURE
FILTRATE ANTIGEN
CFP10A
(Mycobacterium
tuberculosis) 		4 / 8 ILE A  86
ARG A  45
ILE A  42
ILE A   7
 None
 0.78A 2bu8A-3dwmA:
undetectable		 2bu8A-3dwmA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3dwm 9.5 KDA CULTURE
FILTRATE ANTIGEN
CFP10A
(Mycobacterium
tuberculosis) 		3 / 3 ASP A  34
LEU A  35
GLN A  18
 None
 0.66A 3g4lA-3dwmA:
undetectable		 3g4lA-3dwmA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3dwm 9.5 KDA CULTURE
FILTRATE ANTIGEN
CFP10A
(Mycobacterium
tuberculosis) 		4 / 8 ARG A  45
GLU A  36
LEU A  11
THR A  15
 None
 1.01A 5sxqA-3dwmA:
undetectable		 5sxqA-3dwmA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3dwm 9.5 KDA CULTURE
FILTRATE ANTIGEN
CFP10A
(Mycobacterium
tuberculosis) 		4 / 8 ARG A  45
GLU A  36
LEU A  11
THR A  15
 None
 1.00A 5sxtA-3dwmA:
undetectable		 5sxtA-3dwmA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3dwm 9.5 KDA CULTURE
FILTRATE ANTIGEN
CFP10A
(Mycobacterium
tuberculosis) 		4 / 8 VAL A   5
GLY A  29
LEU A  28
THR A  27
 None
 0.97A 5sxtA-3dwmA:
undetectable		 5sxtA-3dwmA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3dwm 9.5 KDA CULTURE
FILTRATE ANTIGEN
CFP10A
(Mycobacterium
tuberculosis) 		4 / 8 ARG A  45
GLU A  36
LEU A  11
THR A  15
 None
 0.99A 5sxtB-3dwmA:
undetectable		 5sxtB-3dwmA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3dwm 9.5 KDA CULTURE
FILTRATE ANTIGEN
CFP10A
(Mycobacterium
tuberculosis) 		4 / 8 VAL A   5
GLY A  29
LEU A  28
THR A  27
 None
 0.97A 5sxtB-3dwmA:
undetectable		 5sxtB-3dwmA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3dwm 9.5 KDA CULTURE
FILTRATE ANTIGEN
CFP10A
(Mycobacterium
tuberculosis) 		4 / 8 ARG A  45
GLU A  36
LEU A  11
THR A  15
 None
 1.00A 5syjB-3dwmA:
undetectable		 5syjB-3dwmA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3dwm 9.5 KDA CULTURE
FILTRATE ANTIGEN
CFP10A
(Mycobacterium
tuberculosis) 		4 / 8 VAL A   5
GLY A  29
LEU A  28
THR A  27
 None
 0.99A 5syjB-3dwmA:
undetectable		 5syjB-3dwmA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3dwm 9.5 KDA CULTURE
FILTRATE ANTIGEN
CFP10A
(Mycobacterium
tuberculosis) 		4 / 8 ILE A  10
THR A   9
THR A  15
SER A   6
 None
 1.11A 6c06C-3dwmA:
undetectable		 6c06C-3dwmA:
undetectable