SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dxi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 3dxi PUTATIVE ALDOLASE
(Bacteroides
vulgatus) 		5 / 8 GLU A  86
ILE A 102
LEU A  78
ALA A 118
VAL A 128
 None
 1.37A 1a29A-3dxiA:
undetectable		 1a29A-3dxiA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 3dxi PUTATIVE ALDOLASE
(Bacteroides
vulgatus) 		5 / 12 LEU A  66
ALA A  30
ILE A 252
THR A 255
ASP A  25
 None
 1.05A 1tw4A-3dxiA:
undetectable		 1tw4A-3dxiA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 3dxi PUTATIVE ALDOLASE
(Bacteroides
vulgatus) 		5 / 12 LEU A  66
LEU A  29
ILE A 252
THR A 255
ASP A  25
 None
 1.15A 1tw4A-3dxiA:
undetectable		 1tw4A-3dxiA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3dxi PUTATIVE ALDOLASE
(Bacteroides
vulgatus) 		5 / 12 THR A 183
LEU A 175
PHE A 130
CYH A 159
VAL A 161
 None
 1.27A 2g72A-3dxiA:
undetectable		 2g72A-3dxiA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WB9_A_CYSA301_0
(GLUTATHIONE
TRANSFERASE SIGMA
CLASS)		 3dxi PUTATIVE ALDOLASE
(Bacteroides
vulgatus) 		4 / 5 TYR A 271
GLY A 223
TYR A  14
TYR A  13
 None
 0.99A 2wb9A-3dxiA:
undetectable		 2wb9A-3dxiA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 3dxi PUTATIVE ALDOLASE
(Bacteroides
vulgatus) 		5 / 10 ALA A 114
ILE A 104
ILE A 102
LEU A  92
ILE A 121
 None
 1.20A 4dtaA-3dxiA:
undetectable		 4dtaA-3dxiA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 3dxi PUTATIVE ALDOLASE
(Bacteroides
vulgatus) 		3 / 3 MET A 101
GLU A 127
LEU A 157
 None
 0.81A 4v2oB-3dxiA:
undetectable		 4v2oB-3dxiA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_2
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 3dxi PUTATIVE ALDOLASE
(Bacteroides
vulgatus) 		4 / 5 LEU A 176
VAL A 172
MET A 135
CYH A 159
 None
 1.34A 5te0A-3dxiA:
undetectable		 5te0A-3dxiA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 3dxi PUTATIVE ALDOLASE
(Bacteroides
vulgatus) 		4 / 8 ILE A 154
ALA A 120
ILE A 115
THR A 123
 None
 0.85A 5uihA-3dxiA:
undetectable		 5uihA-3dxiA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 3dxi PUTATIVE ALDOLASE
(Bacteroides
vulgatus) 		4 / 5 ASN A 131
GLY A 198
HIS A 190
ASP A  10
 None
 0.92A 6gh9A-3dxiA:
undetectable		 6gh9A-3dxiA:
14.14