SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dyj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3dyj TALIN-1
(Mus
musculus) 		4 / 6 ALA A1981
LEU A2033
ASP A2029
LEU A2026
 None
 0.63A 1mt1D-3dyjA:
undetectable
1mt1E-3dyjA:
undetectable		 1mt1D-3dyjA:
16.17
1mt1E-3dyjA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 3dyj TALIN-1
(Mus
musculus) 		4 / 8 MET A2215
PHE A2160
ALA A2244
ASN A2245
 None
 1.10A 1pnlA-3dyjA:
undetectable
1pnlB-3dyjA:
undetectable		 1pnlA-3dyjA:
19.76
1pnlB-3dyjA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3dyj TALIN-1
(Mus
musculus) 		5 / 11 ALA A2189
VAL A2201
LEU A2251
LEU A2255
THR A2257
 None
 1.10A 3kw2A-3dyjA:
undetectable		 3kw2A-3dyjA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3dyj TALIN-1
(Mus
musculus) 		5 / 11 ALA A2189
VAL A2201
LEU A2251
LEU A2255
THR A2257
 None
 1.10A 3kw2B-3dyjA:
undetectable		 3kw2B-3dyjA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3dyj TALIN-1
(Mus
musculus) 		5 / 12 ALA A2244
LEU A2251
LEU A2248
ALA A2185
ILE A2212
 None
 1.18A 3lbdA-3dyjA:
undetectable		 3lbdA-3dyjA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dyj TALIN-1
(Mus
musculus) 		5 / 12 ALA A2023
VAL A2062
ALA A2066
SER A2068
LEU A2069
 None
 0.86A 3ln1A-3dyjA:
undetectable		 3ln1A-3dyjA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dyj TALIN-1
(Mus
musculus) 		5 / 12 ALA A2023
VAL A2062
ALA A2066
SER A2068
LEU A2069
 None
 0.85A 3ln1B-3dyjA:
undetectable		 3ln1B-3dyjA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dyj TALIN-1
(Mus
musculus) 		5 / 12 ALA A2023
VAL A2062
ALA A2066
SER A2068
LEU A2069
 None
 0.85A 3ln1C-3dyjA:
undetectable		 3ln1C-3dyjA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3dyj TALIN-1
(Mus
musculus) 		5 / 12 LEU A2283
ALA A2244
GLY A2246
GLY A2240
LEU A2216
 None
 1.21A 3ou7A-3dyjA:
undetectable		 3ou7A-3dyjA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3dyj TALIN-1
(Mus
musculus) 		5 / 12 LEU A2283
ALA A2244
GLY A2246
GLY A2240
LEU A2216
 None
 1.17A 3ou7B-3dyjA:
undetectable		 3ou7B-3dyjA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3dyj TALIN-1
(Mus
musculus) 		5 / 12 LEU A2283
ALA A2244
GLY A2246
GLY A2240
LEU A2216
 None
 1.20A 3ou7D-3dyjA:
undetectable		 3ou7D-3dyjA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3dyj TALIN-1
(Mus
musculus) 		4 / 8 GLY A2142
TYR A2247
LEU A2251
VAL A2254
 None
 0.70A 4fgzA-3dyjA:
undetectable		 4fgzA-3dyjA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 3dyj TALIN-1
(Mus
musculus) 		5 / 12 ASP A2029
VAL A2087
ALA A2090
VAL A1985
GLY A2092
 None
 1.25A 4mm6A-3dyjA:
undetectable		 4mm6A-3dyjA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 3dyj TALIN-1
(Mus
musculus) 		4 / 5 VAL A2025
GLU A2028
VAL A2032
LYS A2031
 None
 1.39A 4p6vB-3dyjA:
1.6
4p6vE-3dyjA:
3.7		 4p6vB-3dyjA:
21.63
4p6vE-3dyjA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 3dyj TALIN-1
(Mus
musculus) 		5 / 12 HIS A2015
GLU A2010
GLY A2008
GLN A2077
GLY A2070
 None
 1.28A 4uilH-3dyjA:
undetectable
4uilL-3dyjA:
undetectable		 4uilH-3dyjA:
19.70
4uilL-3dyjA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 3dyj TALIN-1
(Mus
musculus) 		5 / 12 SER A2279
GLY A2278
ALA A2277
GLU A2249
THR A2186
 None
 1.12A 4xt8A-3dyjA:
undetectable		 4xt8A-3dyjA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dyj TALIN-1
(Mus
musculus) 		5 / 12 ALA A2023
VAL A2062
ALA A2066
SER A2068
LEU A2069
 None
 0.89A 5jw1A-3dyjA:
undetectable		 5jw1A-3dyjA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dyj TALIN-1
(Mus
musculus) 		6 / 12 ALA A2023
VAL A2062
GLY A2065
ALA A2066
SER A2068
LEU A2069
 None
 1.27A 5kirA-3dyjA:
undetectable		 5kirA-3dyjA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dyj TALIN-1
(Mus
musculus) 		6 / 12 ALA A2023
VAL A2062
GLY A2065
ALA A2066
SER A2068
LEU A2069
 None
 1.33A 5kirB-3dyjA:
undetectable		 5kirB-3dyjA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 3dyj TALIN-1
(Mus
musculus) 		4 / 5 GLN A2077
THR A2076
THR A2140
GLY A2065
 None
 1.19A 6gbnC-3dyjA:
undetectable		 6gbnC-3dyjA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 3dyj TALIN-1
(Mus
musculus) 		4 / 6 SER A2273
ALA A2189
THR A2204
ALA A2211
 None
 1.18A 6ma6A-3dyjA:
undetectable		 6ma6A-3dyjA:
11.86