SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 3dz1 DIHYDRODIPICOLINATE
SYNTHASE
(Rhodopseudomonas
palustris) 		3 / 4 LYS A   2
ALA A 102
MET A  97
 None
 1.05A 1hk3A-3dz1A:
undetectable		 1hk3A-3dz1A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3dz1 DIHYDRODIPICOLINATE
SYNTHASE
(Rhodopseudomonas
palustris) 		4 / 6 GLY A 103
VAL A  81
ALA A  93
SER A  96
 None
 0.91A 1p6kA-3dz1A:
undetectable		 1p6kA-3dz1A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 3dz1 DIHYDRODIPICOLINATE
SYNTHASE
(Rhodopseudomonas
palustris) 		4 / 7 LEU A 137
LEU A 166
PRO A 150
ILE A 153
 None
 0.95A 3s56B-3dz1A:
undetectable		 3s56B-3dz1A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 3dz1 DIHYDRODIPICOLINATE
SYNTHASE
(Rhodopseudomonas
palustris) 		3 / 3 PRO A  15
THR A  16
LEU A  47
 None
 0.77A 3ttrA-3dz1A:
undetectable		 3ttrA-3dz1A:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 3dz1 DIHYDRODIPICOLINATE
SYNTHASE
(Rhodopseudomonas
palustris) 		4 / 5 LEU A 180
LEU A 166
MET A 148
TRP A 135
 None
 1.25A 4do3A-3dz1A:
undetectable		 4do3A-3dz1A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3dz1 DIHYDRODIPICOLINATE
SYNTHASE
(Rhodopseudomonas
palustris) 		3 / 3 SER A 275
ASP A  57
ASP A  21
 None
 0.70A 4uckA-3dz1A:
undetectable		 4uckA-3dz1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 3dz1 DIHYDRODIPICOLINATE
SYNTHASE
(Rhodopseudomonas
palustris) 		4 / 4 LEU A  50
LEU A 260
GLY A 259
GLU A 253
 None
 1.17A 5hhjA-3dz1A:
undetectable		 5hhjA-3dz1A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 3dz1 DIHYDRODIPICOLINATE
SYNTHASE
(Rhodopseudomonas
palustris) 		4 / 4 LEU A  56
LEU A  47
GLY A  51
GLU A  52
 None
 1.24A 5hhjA-3dz1A:
undetectable		 5hhjA-3dz1A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 3dz1 DIHYDRODIPICOLINATE
SYNTHASE
(Rhodopseudomonas
palustris) 		4 / 4 LEU A 224
MET A 207
ILE A  13
LEU A 195
 None
 1.38A 5nfpA-3dz1A:
undetectable		 5nfpA-3dz1A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3dz1 DIHYDRODIPICOLINATE
SYNTHASE
(Rhodopseudomonas
palustris) 		4 / 7 VAL A  79
PRO A 134
ALA A  65
THR A  66
 None
 0.91A 6cduH-3dz1A:
undetectable
6cduI-3dz1A:
undetectable		 6cduH-3dz1A:
20.45
6cduI-3dz1A:
20.45