SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3dzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 8 GLY A 341
PHE A 438
PHE A 439
HIS A 435
 None
None
None
9CR  A7223 (-4.3A)
 1.00A 1ax9A-3dzuA:
undetectable		 1ax9A-3dzuA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3004_0
(BETA-CARBONIC
ANHYDRASE)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 6 CYH D 111
ASP D 116
VAL D 113
GLY D 130
 ZN  D7121 (-2.3A)
None
ZN  D7121 ( 4.6A)
None
 1.21A 1ekjC-3dzuD:
undetectable
1ekjD-3dzuD:
undetectable		 1ekjC-3dzuD:
19.08
1ekjD-3dzuD:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 8 ALA A 272
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.86A 1ereE-3dzuA:
25.4		 1ereE-3dzuA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 8 ALA A 272
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.87A 1ereF-3dzuA:
25.4		 1ereF-3dzuA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 276
TRP A 305
ARG A 316
ILE A 428
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 (-3.7A)
None
 1.03A 1errA-3dzuA:
21.9		 1errA-3dzuA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ILE A 428
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
None
 0.87A 1errB-3dzuA:
22.1		 1errB-3dzuA:
20.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
CYH A 269
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
HIS A 435
 9CR  A7223 (-3.9A)
None
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
 0.71A 1fbyA-3dzuA:
33.1		 1fbyA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
CYH A 269
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
HIS A 435
 9CR  A7223 (-3.9A)
None
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
 0.72A 1fbyB-3dzuA:
32.4		 1fbyB-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.67A 1fm6A-3dzuA:
32.4		 1fm6A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 GLY D 284
MET D 348
LEU D 353
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 4.7A)
None
PLB  D 701 ( 4.8A)
None
None
None
 0.68A 1fm6D-3dzuD:
37.0		 1fm6D-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 GLY D 284
SER D 289
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.93A 1fm6D-3dzuD:
37.0		 1fm6D-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 SER D 289
TYR D 327
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.8A)
None
None
None
 1.12A 1fm6D-3dzuD:
37.0		 1fm6D-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 TYR D 327
LEU D 353
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
None
PLB  D 701 ( 4.8A)
None
None
None
 0.89A 1fm6D-3dzuD:
37.0		 1fm6D-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 4 ILE D 281
LEU D 330
VAL D 339
ILE D 341
 PLB  D 701 (-4.6A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 (-3.6A)
 0.20A 1fm6D-3dzuD:
37.0		 1fm6D-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ALA A 271
ALA A 272
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 428
CYH A 432
LEU A 436
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
None
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 1.47A 1fm6U-3dzuA:
32.6		 1fm6U-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ALA A 271
ALA A 272
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.62A 1fm6U-3dzuA:
32.6		 1fm6U-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 TRP A 305
VAL A 342
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 None
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 1.13A 1fm6U-3dzuA:
32.6		 1fm6U-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 ILE D 281
PHE D 282
GLY D 284
SER D 289
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-4.6A)
None
PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.8A)
None
None
None
 0.71A 1fm6X-3dzuD:
37.1		 1fm6X-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
CYH D 285
TYR D 327
MET D 364
HIS D 449
 None
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.8A)
None
 1.05A 1fm6X-3dzuD:
37.1		 1fm6X-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
GLY D 284
CYH D 285
MET D 364
HIS D 449
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.8A)
None
 1.02A 1fm6X-3dzuD:
37.1		 1fm6X-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
HIS D 323
TYR D 327
HIS D 449
TYR D 473
 None
 1.10A 1fm6X-3dzuD:
37.1		 1fm6X-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
TYR D 327
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
None
PLB  D 701 ( 4.8A)
None
None
None
 0.85A 1fm6X-3dzuD:
37.1		 1fm6X-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.62A 1fm9A-3dzuA:
32.7		 1fm9A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 GLN A 275
ILE A 345
HIS A 435
 9CR  A7223 (-4.6A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-4.3A)
 0.52A 1fm9A-3dzuA:
32.7		 1fm9A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 TRP A 305
LEU A 309
ARG A 316
LEU A 326
ALA A 327
 None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.56A 1g5yB-3dzuA:
25.5		 1g5yB-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 10 LEU A 309
SER A 312
PHE A 313
ARG A 316
LEU A 326
ALA A 327
 9CR  A7223 ( 4.4A)
9CR  A7223 ( 4.0A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.87A 1g5yC-3dzuA:
25.5		 1g5yC-3dzuA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K4T_D_TTCD990_1
(DNA TOPOISOMERASE I)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 5 GLU A 207
ARG A 202
ASP D 337
THR A 168
 None
 1.49A 1k4tA-3dzuA:
0.3		 1k4tA-3dzuA:
20.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.64A 1k74A-3dzuA:
32.8		 1k74A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 GLN A 275
ILE A 345
HIS A 435
 9CR  A7223 (-4.6A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-4.3A)
 0.47A 1k74A-3dzuA:
32.8		 1k74A-3dzuA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 TYR D 327
ILE D 472
VAL D 293
ALA D 331
TYR D 473
 None
 1.03A 1kiaC-3dzuD:
undetectable		 1kiaC-3dzuD:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 TYR D 327
ILE D 472
VAL D 293
ALA D 331
TYR D 473
 None
 1.02A 1nbhA-3dzuD:
undetectable		 1nbhA-3dzuD:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 TYR D 327
ILE D 472
VAL D 293
ALA D 331
TYR D 473
 None
 1.00A 1nbhB-3dzuD:
undetectable		 1nbhB-3dzuD:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 TYR D 327
ILE D 472
VAL D 293
ALA D 331
TYR D 473
 None
 1.01A 1nbhC-3dzuD:
undetectable		 1nbhC-3dzuD:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 TYR D 327
ILE D 472
VAL D 293
ALA D 331
TYR D 473
 None
 1.00A 1nbhD-3dzuD:
undetectable		 1nbhD-3dzuD:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 10 GLY D 174
PHE D 135
VAL D 125
GLY D 124
VAL D 173
 None
 1.24A 1pwyE-3dzuD:
undetectable		 1pwyE-3dzuD:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A7223 (-4.2A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 ( 4.7A)
 0.98A 1qknA-3dzuA:
22.6		 1qknA-3dzuA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A7223 (-4.2A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
None
 0.94A 1qknA-3dzuA:
22.6		 1qknA-3dzuA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RR8_A_TTCA100_1
(DNA TOPOISOMERASE I)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 5 GLU A 207
ARG A 202
ASP D 337
THR A 168
 None
 1.46A 1rr8C-3dzuA:
undetectable		 1rr8C-3dzuA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RRJ_B_TTCB990_1
(DNA TOPOISOMERASE I)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 5 GLU A 207
ARG A 202
ASP D 337
THR A 168
 None
 1.46A 1rrjA-3dzuA:
undetectable		 1rrjA-3dzuA:
20.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ILE A 268
ALA A 271
GLN A 275
TRP A 305
ASN A 306
PHE A 313
ARG A 316
LEU A 326
VAL A 342
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-3.9A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.7A)
 0.76A 1xdkA-3dzuA:
33.7		 1xdkA-3dzuA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.70A 1xdkA-3dzuA:
33.7		 1xdkA-3dzuA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.67A 1xdkE-3dzuA:
33.7		 1xdkE-3dzuA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
CYH A 269
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
None
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.67A 1xiuA-3dzuA:
30.3		 1xiuA-3dzuA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
VAL A 342
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.58A 1xiuB-3dzuA:
33.1		 1xiuB-3dzuA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.64A 1xlsA-3dzuA:
32.9		 1xlsA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.64A 1xlsB-3dzuA:
32.9		 1xlsB-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.64A 1xlsC-3dzuA:
32.9		 1xlsC-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.64A 1xlsD-3dzuA:
32.9		 1xlsD-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 0.97A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.06A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
TYR D 473
LEU D 469
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
None
None
 1.49A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 GLY D 284
SER D 289
LEU D 330
LEU D 353
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
None
None
 0.69A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
GLY D 284
CYH D 285
LEU D 330
MET D 364
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
 1.10A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 PHE D 282
GLY D 284
SER D 289
LEU D 330
LEU D 353
MET D 364
LEU D 469
TYR D 473
 None
PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
None
 0.78A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 TYR D 327
LEU D 330
LEU D 353
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
None
None
 0.88A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 5 ILE D 281
ILE D 326
ILE D 341
MET D 348
 PLB  D 701 (-4.6A)
PLB  D 701 ( 4.5A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
 0.35A 1zgyA-3dzuD:
37.2		 1zgyA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ALA A 271
ALA A 272
GLN A 275
ASN A 306
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ILE A 345
CYH A 432
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-3.9A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.75A 2aclA-3dzuA:
29.9
2aclE-3dzuA:
29.9		 2aclA-3dzuA:
100.00
2aclE-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		8 / 12 GLN A 275
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
 9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.73A 2aclA-3dzuA:
29.9
2aclE-3dzuA:
29.9		 2aclA-3dzuA:
100.00
2aclE-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		8 / 10 ALA A 271
ALA A 272
GLN A 275
ASN A 306
PHE A 313
ARG A 316
ILE A 345
CYH A 432
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-3.9A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.77A 2aclC-3dzuA:
30.1		 2aclC-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 10 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
ALA A 327
ILE A 345
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.81A 2aclC-3dzuA:
30.1		 2aclC-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 11 ALA A 271
ALA A 272
GLN A 275
ASN A 306
LEU A 309
PHE A 313
ARG A 316
ILE A 345
CYH A 432
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-3.9A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.84A 2aclE-3dzuA:
29.9		 2aclE-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 11 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
ILE A 345
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.87A 2aclE-3dzuA:
29.9		 2aclE-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
ASN A 306
LEU A 309
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ALA A 327
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-3.9A)
9CR  A7223 ( 4.4A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 (-3.8A)
 0.86A 2aclG-3dzuA:
29.0		 2aclG-3dzuA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 8 PHE D 363
PHE D 360
GLU D 460
TYR D 473
 None
 1.36A 2aoxA-3dzuD:
undetectable		 2aoxA-3dzuD:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_B_THAB401_1
(HISTAMINE
N-METHYLTRANSFERASE)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 7 PHE D 363
PHE D 360
GLU D 460
TYR D 473
 None
 1.37A 2aoxB-3dzuD:
undetectable		 2aoxB-3dzuD:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 276
TRP A 305
ILE A 345
LEU A 436
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.9A)
9CR  A7223 ( 4.7A)
 0.85A 2jfaA-3dzuA:
22.7		 2jfaA-3dzuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
ILE A 428
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
 1.02A 2jfaA-3dzuA:
22.7		 2jfaA-3dzuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.87A 2jfaA-3dzuA:
22.7		 2jfaA-3dzuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
GLY A 429
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
 0.88A 2jfaB-3dzuA:
22.3		 2jfaB-3dzuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.87A 2jfaB-3dzuA:
22.3		 2jfaB-3dzuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens;
Homo
sapiens) 		5 / 12 GLN D 410
ALA A 416
GLN A 411
ASP D 396
LEU A 420
 None
 1.03A 2nv4A-3dzuD:
undetectable		 2nv4A-3dzuD:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 5 LEU D 442
VAL A 396
LEU A 400
ARG A 371
 None
 1.10A 2oiqA-3dzuD:
undetectable		 2oiqA-3dzuD:
20.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 None
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.12A 2prgA-3dzuD:
36.9		 2prgA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
GLY D 284
CYH D 285
GLN D 286
LEU D 330
MET D 364
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
 1.01A 2prgA-3dzuD:
36.9		 2prgA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
GLY D 284
CYH D 285
LEU D 330
MET D 364
HIS D 449
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.09A 2prgA-3dzuD:
36.9		 2prgA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
GLY D 284
GLN D 286
LEU D 330
MET D 348
MET D 364
TYR D 473
 None
PLB  D 701 (-3.3A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
 0.67A 2prgA-3dzuD:
36.9		 2prgA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
GLY D 284
LEU D 330
MET D 348
MET D 364
HIS D 449
TYR D 473
 None
PLB  D 701 (-3.3A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
 0.76A 2prgA-3dzuD:
36.9		 2prgA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
HIS D 323
TYR D 327
HIS D 449
TYR D 473
 None
 1.07A 2prgA-3dzuD:
36.9		 2prgA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
TYR D 327
LEU D 330
MET D 364
HIS D 449
TYR D 473
 None
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 1.00A 2prgA-3dzuD:
36.9		 2prgA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 CYH D 285
TYR D 327
LEU D 330
VAL D 339
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
 0.93A 2prgB-3dzuD:
35.8		 2prgB-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
CYH D 285
LEU D 330
VAL D 339
MET D 364
 None
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
 1.00A 2prgB-3dzuD:
35.8		 2prgB-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
SER D 289
LEU D 330
VAL D 339
MET D 364
LEU D 469
TYR D 473
 None
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
None
 0.72A 2prgB-3dzuD:
35.8		 2prgB-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 SER D 289
LEU D 330
VAL D 339
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
None
None
 0.81A 2prgB-3dzuD:
35.8		 2prgB-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 TYR D 327
LEU D 330
VAL D 339
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
None
None
 0.95A 2prgB-3dzuD:
35.8		 2prgB-3dzuD:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 7 LEU A 367
LEU A 425
ILE A 373
GLU A 239
 None
 1.05A 2qqdA-3dzuA:
undetectable
2qqdE-3dzuA:
undetectable		 2qqdA-3dzuA:
9.07
2qqdE-3dzuA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
ILE A 428
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
 0.99A 2qxsA-3dzuA:
22.9		 2qxsA-3dzuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.80A 2qxsA-3dzuA:
22.9		 2qxsA-3dzuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
ILE A 428
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
 1.01A 2qxsB-3dzuA:
22.8		 2qxsB-3dzuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.83A 2qxsB-3dzuA:
22.8		 2qxsB-3dzuA:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
HIS D 323
TYR D 327
HIS D 449
TYR D 473
 PLB  D 701 (-3.2A)
None
None
None
None
 1.22A 2xkwA-3dzuD:
37.5		 2xkwA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		9 / 12 CYH D 285
SER D 289
LEU D 330
ILE D 341
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.69A 2xkwA-3dzuD:
37.5		 2xkwA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		9 / 12 CYH D 285
TYR D 327
LEU D 330
ILE D 341
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.84A 2xkwA-3dzuD:
37.5		 2xkwA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		9 / 12 PHE D 282
CYH D 285
SER D 289
LEU D 330
ILE D 341
MET D 348
MET D 364
LEU D 469
TYR D 473
 None
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
 0.49A 2xkwA-3dzuD:
37.5		 2xkwA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 7 LEU D 255
ILE D 281
GLN D 286
ALA D 292
ILE D 326
 None
PLB  D 701 (-4.6A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.5A)
 0.68A 2xkwA-3dzuD:
37.5		 2xkwA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 ILE D 249
CYH D 285
SER D 289
ALA D 292
LEU D 330
ILE D 341
MET D 348
MET D 364
 None
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
 0.40A 2xkwB-3dzuD:
34.5		 2xkwB-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 6 LEU D 255
ARG D 280
ILE D 281
ILE D 326
MET D 329
LEU D 333
 None
None
PLB  D 701 (-4.6A)
PLB  D 701 ( 4.5A)
None
PLB  D 701 (-4.4A)
 0.66A 2xkwB-3dzuD:
34.5		 2xkwB-3dzuD:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 5 ALA A 136
GLY A 154
CYH A 155
LYS A 156
 None
None
ZN  A7221 (-2.5A)
None
 1.30A 2yldA-3dzuA:
undetectable		 2yldA-3dzuA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 5 ALA A 136
GLY A 154
CYH A 155
LYS A 156
 None
None
ZN  A7221 (-2.5A)
None
 1.21A 2ylgA-3dzuA:
undetectable		 2ylgA-3dzuA:
16.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 10 ARG D 280
ILE D 281
GLY D 284
CYH D 285
LEU D 330
ILE D 341
MET D 348
MET D 364
 None
PLB  D 701 (-4.6A)
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
 0.66A 3adsA-3dzuD:
37.2		 3adsA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 CYH D 285
SER D 289
LEU D 330
LEU D 353
PHE D 363
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
None
None
None
None
 0.85A 3adsA-3dzuD:
37.2		 3adsA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
CYH D 285
SER D 289
LEU D 353
PHE D 363
HIS D 449
LEU D 469
 None
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
None
None
None
None
 1.00A 3adsA-3dzuD:
37.2		 3adsA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 6 ILE D 281
ILE D 326
LEU D 356
PHE D 360
MET D 364
 PLB  D 701 (-4.6A)
PLB  D 701 ( 4.5A)
None
None
PLB  D 701 ( 4.8A)
 0.54A 3adsA-3dzuD:
37.2		 3adsA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 6 ILE D 326
TYR D 327
LEU D 356
PHE D 360
MET D 364
 PLB  D 701 ( 4.5A)
None
None
None
PLB  D 701 ( 4.8A)
 0.62A 3adsA-3dzuD:
37.2		 3adsA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		10 / 12 ILE D 281
CYH D 285
SER D 289
ALA D 292
ILE D 326
LEU D 330
LEU D 333
VAL D 339
ILE D 341
MET D 364
 PLB  D 701 (-4.6A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-4.4A)
None
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
 0.54A 3adsB-3dzuD:
34.0		 3adsB-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		10 / 12 ILE D 281
GLY D 284
CYH D 285
SER D 289
ALA D 292
ILE D 326
LEU D 330
VAL D 339
ILE D 341
MET D 364
 PLB  D 701 (-4.6A)
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
 0.45A 3adsB-3dzuD:
34.0		 3adsB-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 CYH D 285
GLN D 286
SER D 289
LEU D 330
LEU D 353
PHE D 363
LEU D 469
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
None
None
 0.79A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 CYH D 285
GLN D 286
SER D 289
TYR D 327
LEU D 330
LEU D 353
HIS D 449
LEU D 469
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.1A)
None
None
None
 0.74A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
HIS D 323
TYR D 327
HIS D 449
TYR D 473
 PLB  D 701 (-3.2A)
None
None
None
None
 1.26A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 CYH D 285
SER D 289
LEU D 330
LEU D 353
PHE D 363
LEU D 469
TYR D 473
 PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
None
None
None
 0.68A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 CYH D 285
SER D 289
TYR D 327
LEU D 330
LEU D 353
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.1A)
None
None
None
None
 0.78A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
GLN D 286
SER D 289
LEU D 353
PHE D 363
LEU D 469
 None
None
PLB  D 701 ( 3.9A)
None
None
None
 1.03A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
GLN D 286
SER D 289
TYR D 327
LEU D 353
HIS D 449
LEU D 469
 None
None
PLB  D 701 ( 3.9A)
None
None
None
None
 0.84A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 7 ILE D 281
ILE D 326
LEU D 356
PHE D 360
MET D 364
 PLB  D 701 (-4.6A)
PLB  D 701 ( 4.5A)
None
None
PLB  D 701 ( 4.8A)
 0.51A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 7 ILE D 281
LEU D 356
PHE D 360
MET D 364
LYS D 367
 PLB  D 701 (-4.6A)
None
None
PLB  D 701 ( 4.8A)
None
 1.09A 3adxA-3dzuD:
37.0		 3adxA-3dzuD:
94.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		11 / 12 LEU D 228
GLY D 284
CYH D 285
SER D 289
ALA D 292
ILE D 326
LEU D 330
LEU D 333
VAL D 339
ILE D 341
MET D 364
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-4.4A)
None
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
 0.61A 3adxB-3dzuD:
34.2		 3adxB-3dzuD:
94.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 5 LEU D 384
THR D 328
HIS D 425
LEU D 431
 None
 1.14A 3ce6D-3dzuD:
undetectable		 3ce6D-3dzuD:
21.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 GLY D 284
CYH D 285
HIS D 323
LEU D 330
MET D 364
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 0.68A 3cs8A-3dzuD:
36.3		 3cs8A-3dzuD:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 GLY D 284
CYH D 285
ILE D 326
LEU D 330
MET D 364
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 0.61A 3cs8A-3dzuD:
36.3		 3cs8A-3dzuD:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 GLY D 284
CYH D 285
LEU D 330
MET D 364
HIS D 449
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 1.10A 3cs8A-3dzuD:
36.3		 3cs8A-3dzuD:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 GLY D 284
SER D 289
ILE D 326
LEU D 330
MET D 364
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 0.76A 3cs8A-3dzuD:
36.3		 3cs8A-3dzuD:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 GLY D 284
SER D 289
LEU D 330
MET D 364
HIS D 449
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 1.17A 3cs8A-3dzuD:
36.3		 3cs8A-3dzuD:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 HIS D 323
LEU D 330
MET D 364
LYS D 367
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
None
 0.95A 3cs8A-3dzuD:
36.3		 3cs8A-3dzuD:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 ILE D 326
LEU D 330
MET D 364
LYS D 367
LEU D 469
TYR D 473
 PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
None
 0.86A 3cs8A-3dzuD:
36.3		 3cs8A-3dzuD:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
GLN A 275
ASN A 306
SER A 312
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.6A)
9CR  A7223 (-3.9A)
9CR  A7223 ( 4.0A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.67A 3dzyA-3dzuA:
34.1		 3dzyA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ILE A 268
ALA A 272
SER A 312
PHE A 313
VAL A 342
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.2A)
9CR  A7223 ( 4.0A)
9CR  A7223 (-4.5A)
9CR  A7223 ( 4.5A)
 1.13A 3dzyA-3dzuA:
34.1		 3dzyA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 PHE D 282
CYH D 285
HIS D 323
TYR D 327
VAL D 339
LEU D 353
MET D 364
HIS D 449
 None
PLB  D 701 (-3.2A)
None
None
None
None
PLB  D 701 ( 4.8A)
None
 0.96A 3dzyD-3dzuD:
44.4		 3dzyD-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 PHE D 282
CYH D 285
TYR D 327
LEU D 330
VAL D 339
LEU D 353
MET D 364
HIS D 449
 None
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
None
None
PLB  D 701 ( 4.8A)
None
 0.90A 3dzyD-3dzuD:
44.4		 3dzyD-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 PHE D 282
HIS D 323
TYR D 327
VAL D 339
LEU D 353
MET D 364
HIS D 449
TYR D 473
 None
None
None
None
None
PLB  D 701 ( 4.8A)
None
None
 0.89A 3dzyD-3dzuD:
44.4		 3dzyD-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		9 / 12 PHE D 282
SER D 289
TYR D 327
LEU D 330
VAL D 339
LEU D 353
MET D 364
HIS D 449
TYR D 473
 None
PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.1A)
None
None
PLB  D 701 ( 4.8A)
None
None
 0.89A 3dzyD-3dzuD:
44.4		 3dzyD-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ALA A 271
ALA A 272
GLN A 275
TRP A 305
ASN A 306
PHE A 313
ARG A 316
VAL A 342
ILE A 345
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-3.9A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
 0.74A 3e00A-3dzuA:
34.6		 3e00A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
ALA A 327
VAL A 342
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
 0.60A 3e00A-3dzuA:
34.6		 3e00A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
VAL A 342
ILE A 345
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.51A 3e00A-3dzuA:
34.6		 3e00A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 10 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
ALA A 327
VAL A 342
ILE A 345
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.78A 3falA-3dzuA:
29.5		 3falA-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 10 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.79A 3falC-3dzuA:
29.8		 3falC-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 11 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.72A 3fc6A-3dzuA:
30.5		 3fc6A-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		7 / 11 ILE A 268
ALA A 271
GLN A 275
PHE A 313
ARG A 316
ALA A 327
ILE A 345
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
 1.50A 3fc6A-3dzuA:
30.5		 3fc6A-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 VAL A 265
CYH A 269
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
 9CR  A7223 ( 4.5A)
None
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
 0.71A 3fc6C-3dzuA:
30.3		 3fc6C-3dzuA:
51.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens;
Homo
sapiens) 		5 / 12 GLN D 437
LEU A 422
THR D 440
TYR A 397
LEU A 400
 None
 1.08A 3fsuA-3dzuD:
undetectable		 3fsuA-3dzuD:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_E_C2FE995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens;
Homo
sapiens) 		5 / 11 GLN D 437
LEU A 422
THR D 440
TYR A 397
LEU A 400
 None
 1.10A 3fsuE-3dzuD:
undetectable		 3fsuE-3dzuD:
21.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 SER D 289
MET D 334
MET D 364
HIS D 449
TYR D 473
 PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.8A)
None
None
 1.33A 3g8iA-3dzuD:
34.3		 3g8iA-3dzuD:
61.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 7 LEU D 255
GLN D 286
LEU D 330
LEU D 353
LEU D 469
 None
None
PLB  D 701 ( 4.1A)
None
None
 0.72A 3g8iA-3dzuD:
34.3		 3g8iA-3dzuD:
61.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
LEU D 330
VAL D 339
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
None
None
 0.91A 3g9eA-3dzuD:
37.2		 3g9eA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
LEU D 330
VAL D 339
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
None
None
 0.93A 3g9eA-3dzuD:
37.2		 3g9eA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 GLY D 284
LEU D 330
VAL D 339
ILE D 341
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 (-3.6A)
None
None
None
 0.68A 3g9eA-3dzuD:
37.2		 3g9eA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 GLY D 284
SER D 289
ILE D 341
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 (-3.6A)
None
None
None
 0.91A 3g9eA-3dzuD:
37.2		 3g9eA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 HIS D 323
TYR D 327
HIS D 449
LEU D 469
TYR D 473
 None
 1.19A 3g9eA-3dzuD:
37.2		 3g9eA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 SER D 289
TYR D 327
ILE D 341
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
None
PLB  D 701 (-3.6A)
None
None
None
 1.00A 3g9eA-3dzuD:
37.2		 3g9eA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 TYR D 327
LEU D 330
VAL D 339
ILE D 341
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
None
PLB  D 701 (-3.6A)
None
None
None
 0.80A 3g9eA-3dzuD:
37.2		 3g9eA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 10 PHE D 282
GLN D 286
ILE D 326
MET D 329
LEU D 353
 None
None
PLB  D 701 ( 4.5A)
None
None
 0.70A 3gwxA-3dzuD:
34.3		 3gwxA-3dzuD:
42.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLU D 295
LEU D 330
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
None
None
None
 1.03A 3gwxB-3dzuD:
34.4		 3gwxB-3dzuD:
42.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU D 255
PHE D 282
GLN D 286
ILE D 326
MET D 329
LEU D 353
 None
None
None
PLB  D 701 ( 4.5A)
None
None
 0.72A 3gwxB-3dzuD:
34.4		 3gwxB-3dzuD:
42.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		8 / 12 ALA A 271
ALA A 272
GLN A 275
TRP A 305
LEU A 309
ARG A 316
LEU A 326
LEU A 436
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.78A 3h0aA-3dzuA:
31.5		 3h0aA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ALA A 271
ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 326
VAL A 342
ILE A 345
LEU A 436
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 ( 4.7A)
 0.74A 3h0aA-3dzuA:
31.5		 3h0aA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 271
GLN A 275
TRP A 305
ARG A 316
LEU A 326
ILE A 428
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
None
 1.35A 3h0aA-3dzuA:
31.5		 3h0aA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		7 / 12 ALA A 271
LEU A 309
ARG A 316
LEU A 326
VAL A 342
ILE A 345
CYH A 432
 9CR  A7223 (-3.5A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.93A 3h0aA-3dzuA:
31.5		 3h0aA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 ILE A 268
PHE A 313
HIS A 435
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.5A)
9CR  A7223 (-4.3A)
 0.66A 3h0aA-3dzuA:
31.5		 3h0aA-3dzuA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 CYH A 269
PRO A 264
ASP A 444
 None
 0.97A 3hlwB-3dzuA:
undetectable		 3hlwB-3dzuA:
21.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
ILE A 345
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.62A 3oapA-3dzuA:
33.9		 3oapA-3dzuA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A7223 (-4.2A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
None
 0.99A 3q95A-3dzuA:
25.5		 3q95A-3dzuA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A7223 (-4.2A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
None
 1.01A 3q95B-3dzuA:
25.0		 3q95B-3dzuA:
20.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 ALA D 292
LEU D 330
ILE D 341
MET D 348
MET D 364
HIS D 449
 PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
 1.10A 3qt0A-3dzuD:
36.1		 3qt0A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 ALA D 292
TYR D 327
LEU D 330
ILE D 341
MET D 364
HIS D 449
 PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
None
 1.16A 3qt0A-3dzuD:
36.1		 3qt0A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 CYH D 285
ALA D 292
TYR D 327
LEU D 330
ILE D 341
HIS D 449
 PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
None
 1.12A 3qt0A-3dzuD:
36.1		 3qt0A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 SER D 289
ALA D 292
ILE D 341
MET D 348
HIS D 449
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
None
 0.87A 3qt0A-3dzuD:
36.1		 3qt0A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 SER D 289
ALA D 292
TYR D 327
ILE D 341
HIS D 449
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 (-3.6A)
None
 0.97A 3qt0A-3dzuD:
36.1		 3qt0A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP6_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
SER D 289
MET D 364
HIS D 449
TYR D 473
 None
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.8A)
None
None
 0.70A 3sp6A-3dzuD:
35.5		 3sp6A-3dzuD:
43.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU D 255
PHE D 282
ILE D 326
HIS D 449
TYR D 473
 None
None
PLB  D 701 ( 4.5A)
None
None
 1.30A 3sp9A-3dzuD:
34.5		 3sp9A-3dzuD:
42.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU D 255
PHE D 282
ILE D 326
HIS D 449
TYR D 473
 None
None
PLB  D 701 ( 4.5A)
None
None
 1.29A 3sp9B-3dzuD:
34.3		 3sp9B-3dzuD:
42.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
VAL A 342
ILE A 345
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.55A 3uvvB-3dzuA:
34.1		 3uvvB-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ILE A 268
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
VAL A 342
ILE A 345
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.62A 3uvvB-3dzuA:
34.1		 3uvvB-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ILE A 268
ALA A 272
PHE A 313
VAL A 342
ILE A 345
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.5A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
 1.25A 3uvvB-3dzuA:
34.1		 3uvvB-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
CYH D 285
TYR D 327
LEU D 330
LEU D 353
MET D 364
HIS D 449
 None
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
 1.03A 3vn2A-3dzuD:
37.7		 3vn2A-3dzuD:
93.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		10 / 12 PHE D 282
SER D 289
HIS D 323
ILE D 326
TYR D 327
LEU D 330
LEU D 353
MET D 364
HIS D 449
TYR D 473
 None
PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.5A)
None
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.8A)
None
None
 0.86A 3vn2A-3dzuD:
37.7		 3vn2A-3dzuD:
93.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 SER D 289
HIS D 323
ILE D 326
LEU D 330
PHE D 282
TYR D 473
 PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
None
None
 1.31A 3vn2A-3dzuD:
37.7		 3vn2A-3dzuD:
93.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 5 ALA A 136
GLY A 154
CYH A 155
LYS A 156
 None
None
ZN  A7221 (-2.5A)
None
 1.33A 3zwiA-3dzuA:
undetectable		 3zwiA-3dzuA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 368
VAL D 339
ILE D 341
GLU D 365
ILE D 445
 None
None
PLB  D 701 (-3.6A)
None
None
 1.16A 4a97B-3dzuD:
undetectable
4a97C-3dzuD:
undetectable		 4a97B-3dzuD:
21.48
4a97C-3dzuD:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 8 PHE D 368
VAL D 339
ILE D 341
GLU D 365
 None
None
PLB  D 701 (-3.6A)
None
 1.10A 4a97C-3dzuD:
0.9		 4a97C-3dzuD:
21.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 0.94A 4emaA-3dzuD:
37.4		 4emaA-3dzuD:
90.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.06A 4emaA-3dzuD:
37.4		 4emaA-3dzuD:
90.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
TYR D 473
LEU D 469
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
None
None
 1.45A 4emaA-3dzuD:
37.4		 4emaA-3dzuD:
90.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 GLY D 284
SER D 289
LEU D 330
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.73A 4emaA-3dzuD:
37.4		 4emaA-3dzuD:
90.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 TYR D 327
LEU D 330
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.89A 4emaA-3dzuD:
37.4		 4emaA-3dzuD:
90.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		3 / 3 PHE D 282
VAL D 339
ILE D 341
 None
None
PLB  D 701 (-3.6A)
 0.18A 4emaA-3dzuD:
37.4		 4emaA-3dzuD:
90.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ALA A 271
ALA A 272
GLN A 275
LEU A 309
ILE A 310
PHE A 313
ARG A 316
LEU A 326
VAL A 349
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
None
 0.51A 4k6iA-3dzuA:
33.7		 4k6iA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		8 / 12 GLN A 275
LEU A 309
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 349
 9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
None
 0.63A 4k6iA-3dzuA:
33.7		 4k6iA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
ILE A 310
PHE A 313
ARG A 316
VAL A 349
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
None
 0.54A 4k6iA-3dzuA:
33.7		 4k6iA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ILE A 268
ILE A 310
PHE A 313
ARG A 316
CYH A 432
 9CR  A7223 (-3.9A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
 1.01A 4k6iA-3dzuA:
33.7		 4k6iA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ILE A 310
PHE A 313
ARG A 316
LEU A 326
CYH A 432
 None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 (-3.8A)
 0.95A 4k6iA-3dzuA:
33.7		 4k6iA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 LEU A 309
ILE A 310
PHE A 313
ALA A 271
VAL A 349
 9CR  A7223 ( 4.4A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.5A)
None
 1.10A 4k6iA-3dzuA:
33.7		 4k6iA-3dzuA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 8 SER D 394
GLU D 407
GLN D 410
THR D 440
 None
 1.07A 4lnwA-3dzuD:
22.3		 4lnwA-3dzuD:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 6 SER D 394
GLU D 407
GLN D 410
THR D 440
 None
 1.03A 4lnxA-3dzuD:
22.3		 4lnxA-3dzuD:
24.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 11 ILE A 268
ALA A 272
GLN A 275
PHE A 313
ARG A 316
ALA A 327
VAL A 342
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.76A 4nqaA-3dzuA:
32.2		 4nqaA-3dzuA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 11 ILE A 268
ALA A 272
GLN A 275
PHE A 313
LEU A 326
ALA A 327
VAL A 342
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.74A 4nqaA-3dzuA:
32.2		 4nqaA-3dzuA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.66A 4nqaH-3dzuA:
32.4		 4nqaH-3dzuA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.73A 4nqaH-3dzuA:
32.4		 4nqaH-3dzuA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
VAL D 339
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
None
PLB  D 701 ( 4.8A)
None
 0.93A 4o8fA-3dzuD:
35.9		 4o8fA-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 HIS D 323
TYR D 327
VAL D 339
HIS D 449
TYR D 473
 None
 1.16A 4o8fA-3dzuD:
35.9		 4o8fA-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
ARG D 288
SER D 289
MET D 348
LEU D 469
TYR D 473
 None
PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.7A)
None
None
 1.10A 4o8fA-3dzuD:
35.9		 4o8fA-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
SER D 289
VAL D 339
MET D 348
MET D 364
LEU D 469
TYR D 473
 None
PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
 0.56A 4o8fA-3dzuD:
35.9		 4o8fA-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 SER D 289
VAL D 339
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.81A 4o8fA-3dzuD:
35.9		 4o8fA-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 TYR D 327
VAL D 339
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
None
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.94A 4o8fA-3dzuD:
35.9		 4o8fA-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 5 GLY D 284
LEU D 330
ILE D 341
LEU D 353
 PLB  D 701 (-3.3A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
None
 0.29A 4o8fA-3dzuD:
35.9		 4o8fA-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 CYH D 285
LEU D 330
VAL D 339
MET D 348
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
 0.81A 4o8fB-3dzuD:
20.5		 4o8fB-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 LEU D 330
VAL D 339
MET D 348
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
None
None
 0.72A 4o8fB-3dzuD:
20.5		 4o8fB-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 SER D 289
LEU D 330
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
None
None
 0.94A 4o8fB-3dzuD:
20.5		 4o8fB-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 6 ILE D 281
PHE D 282
GLY D 284
ILE D 326
ILE D 341
LEU D 353
 PLB  D 701 (-4.6A)
None
PLB  D 701 (-3.3A)
PLB  D 701 ( 4.5A)
PLB  D 701 (-3.6A)
None
 0.75A 4o8fB-3dzuD:
20.5		 4o8fB-3dzuD:
94.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 8 CYH D 285
SER D 289
LEU D 330
LEU D 333
VAL D 339
ILE D 341
MET D 364
 PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-4.4A)
None
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
 0.48A 4oj4A-3dzuD:
34.2		 4oj4A-3dzuD:
91.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 8 MET D 463
LEU D 453
HIS D 449
ILE D 326
 None
None
None
PLB  D 701 ( 4.5A)
 0.97A 4ok1A-3dzuD:
18.1		 4ok1A-3dzuD:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 CYH A 269
PRO A 264
ASP A 444
 None
 1.01A 4pm5A-3dzuA:
undetectable		 4pm5A-3dzuA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		3 / 3 ARG D 136
GLU D 129
TYR D 123
 None
 1.00A 4r29D-3dzuD:
undetectable		 4r29D-3dzuD:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
ASP A 273
LEU A 276
TRP A 305
ARG A 316
 9CR  A7223 (-4.2A)
None
None
None
9CR  A7223 (-3.7A)
 1.30A 4xi3A-3dzuA:
22.8		 4xi3A-3dzuA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
ASP A 273
LEU A 276
TRP A 305
LEU A 309
ARG A 316
 9CR  A7223 (-4.2A)
None
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
 1.25A 4xi3B-3dzuA:
22.7		 4xi3B-3dzuA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
ASP A 273
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 1.04A 4xi3B-3dzuA:
22.7		 4xi3B-3dzuA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		7 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
None
 1.03A 4xi3B-3dzuA:
22.7		 4xi3B-3dzuA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
GLY A 429
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
 0.92A 4xi3C-3dzuA:
22.5		 4xi3C-3dzuA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.85A 4xi3C-3dzuA:
22.5		 4xi3C-3dzuA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.85A 4xi3D-3dzuA:
22.9		 4xi3D-3dzuA:
19.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
TYR D 473
LEU D 469
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
None
None
 1.42A 4xldA-3dzuD:
37.2		 4xldA-3dzuD:
69.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
CYH D 285
TYR D 327
LEU D 330
HIS D 449
 None
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
None
 1.09A 4xldA-3dzuD:
37.2		 4xldA-3dzuD:
69.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
GLY D 284
CYH D 285
LEU D 330
MET D 364
HIS D 449
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 0.96A 4xldA-3dzuD:
37.2		 4xldA-3dzuD:
69.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 PHE D 282
GLY D 284
SER D 289
LEU D 330
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
None
 0.79A 4xldA-3dzuD:
37.2		 4xldA-3dzuD:
69.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
HIS D 323
TYR D 327
HIS D 449
TYR D 473
 None
 1.03A 4xldA-3dzuD:
37.2		 4xldA-3dzuD:
69.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
TYR D 327
LEU D 330
HIS D 449
LEU D 469
TYR D 473
 None
None
PLB  D 701 ( 4.1A)
None
None
None
 0.86A 4xldA-3dzuD:
37.2		 4xldA-3dzuD:
69.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 9 CYH D 285
SER D 289
ALA D 292
GLU D 295
MET D 329
LEU D 330
LEU D 333
ILE D 341
 PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
None
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-4.4A)
PLB  D 701 (-3.6A)
 0.62A 4xtaA-3dzuD:
34.8		 4xtaA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 8 ILE D 281
CYH D 285
SER D 289
LEU D 330
LEU D 333
ILE D 341
MET D 364
 PLB  D 701 (-4.6A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-4.4A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
 0.46A 4xtaB-3dzuD:
33.7		 4xtaB-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
ILE D 326
MET D 364
HIS D 449
LEU D 469
 None
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.8A)
None
None
 1.02A 4xumA-3dzuD:
37.0		 4xumA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
ILE D 326
PHE D 363
MET D 364
LEU D 469
 None
PLB  D 701 ( 4.5A)
None
PLB  D 701 ( 4.8A)
None
 1.16A 4xumA-3dzuD:
37.0		 4xumA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
PHE D 363
MET D 364
LEU D 465
LEU D 469
 None
None
PLB  D 701 ( 4.8A)
None
None
 1.24A 4xumA-3dzuD:
37.0		 4xumA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 SER D 289
ILE D 326
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.8A)
None
None
None
 0.84A 4xumA-3dzuD:
37.0		 4xumA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 SER D 289
ILE D 326
PHE D 363
MET D 364
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.5A)
None
PLB  D 701 ( 4.8A)
None
None
 0.65A 4xumA-3dzuD:
37.0		 4xumA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 SER D 289
PHE D 363
MET D 364
LEU D 465
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.8A)
None
None
None
 0.71A 4xumA-3dzuD:
37.0		 4xumA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 7 ILE D 281
LEU D 330
ILE D 341
MET D 348
 PLB  D 701 (-4.6A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
 0.49A 4xumA-3dzuD:
37.0		 4xumA-3dzuD:
91.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		10 / 11 GLY D 284
CYH D 285
SER D 289
ALA D 292
ILE D 326
MET D 329
LEU D 330
LEU D 333
ILE D 341
MET D 348
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.5A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-4.4A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
 0.53A 4xumB-3dzuD:
34.1		 4xumB-3dzuD:
91.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens;
Homo
sapiens) 		4 / 7 PHE A 159
ARG A 202
ASP D 337
TYR A 169
 None
 1.25A 5a06A-3dzuA:
undetectable		 5a06A-3dzuA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens;
Homo
sapiens) 		4 / 7 PHE A 159
ARG A 202
ASP D 337
TYR A 169
 None
 1.24A 5a06C-3dzuA:
undetectable		 5a06C-3dzuA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens;
Homo
sapiens) 		4 / 7 PHE A 159
ARG A 202
ASP D 337
TYR A 169
 None
 1.25A 5a06D-3dzuA:
undetectable		 5a06D-3dzuA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens;
Homo
sapiens) 		4 / 7 PHE A 159
ARG A 202
ASP D 337
TYR A 169
 None
 1.25A 5a06E-3dzuA:
undetectable		 5a06E-3dzuA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens;
Homo
sapiens) 		4 / 7 PHE A 159
ARG A 202
ASP D 337
TYR A 169
 None
 1.27A 5a06F-3dzuA:
undetectable		 5a06F-3dzuA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 TYR A 147
LYS A 160
LYS A 156
 None
 1.10A 5dbyA-3dzuA:
undetectable		 5dbyA-3dzuA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		4 / 6 PHE D 387
MET D 439
LEU D 413
LEU D 417
 None
 1.09A 5dzke-3dzuD:
undetectable
5dzks-3dzuD:
undetectable		 5dzke-3dzuD:
20.76
5dzks-3dzuD:
1.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 SER A 355
LEU A 367
MET A 362
 None
 0.80A 5ikrB-3dzuA:
0.9		 5ikrB-3dzuA:
21.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 11 ILE A 268
GLN A 275
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.6A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.62A 5ji0A-3dzuA:
33.8		 5ji0A-3dzuA:
59.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 0.97A 5ji0D-3dzuD:
38.1		 5ji0D-3dzuD:
89.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.11A 5ji0D-3dzuD:
38.1		 5ji0D-3dzuD:
89.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 GLY D 284
SER D 289
LEU D 330
MET D 364
HIS D 449
TYR D 473
 PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 0.87A 5ji0D-3dzuD:
38.1		 5ji0D-3dzuD:
89.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
GLY D 284
CYH D 285
GLN D 286
LEU D 330
MET D 364
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
 1.08A 5ji0D-3dzuD:
38.1		 5ji0D-3dzuD:
89.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
GLY D 284
GLN D 286
SER D 289
LEU D 330
MET D 364
TYR D 473
 None
PLB  D 701 (-3.3A)
None
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.00A 5ji0D-3dzuD:
38.1		 5ji0D-3dzuD:
89.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 TYR D 327
LEU D 330
MET D 364
HIS D 449
TYR D 473
 None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 0.97A 5ji0D-3dzuD:
38.1		 5ji0D-3dzuD:
89.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 5 ALA A 136
GLY A 154
CYH A 155
LYS A 156
 None
None
ZN  A7221 (-2.5A)
None
 1.18A 5jliA-3dzuA:
undetectable		 5jliA-3dzuA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 5 ALA A 136
GLY A 154
CYH A 155
LYS A 156
 None
None
ZN  A7221 (-2.5A)
None
 1.22A 5jt4A-3dzuA:
undetectable		 5jt4A-3dzuA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 LEU A 276
LEU A 279
TRP A 282
 None
 0.83A 5nwuA-3dzuA:
undetectable		 5nwuA-3dzuA:
7.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.81A 5uanA-3dzuA:
32.9		 5uanA-3dzuA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 0.94A 5y2oA-3dzuD:
37.7		 5y2oA-3dzuD:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
SER D 289
LEU D 330
MET D 364
LEU D 469
TYR D 473
 None
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
 0.61A 5y2oA-3dzuD:
37.7		 5y2oA-3dzuD:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 SER D 289
LEU D 330
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
None
 0.67A 5y2oA-3dzuD:
37.7		 5y2oA-3dzuD:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 TYR D 327
LEU D 330
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
None
None
 0.90A 5y2oA-3dzuD:
37.7		 5y2oA-3dzuD:
35.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 0.98A 5y2tA-3dzuD:
36.6		 5y2tA-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.07A 5y2tA-3dzuD:
36.6		 5y2tA-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 GLY D 284
LEU D 330
ILE D 341
MET D 348
MET D 364
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
 0.80A 5y2tA-3dzuD:
36.6		 5y2tA-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 LEU D 255
PHE D 282
GLY D 284
GLN D 286
LEU D 330
ILE D 341
MET D 348
MET D 364
 None
None
PLB  D 701 (-3.3A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
 0.52A 5y2tA-3dzuD:
36.6		 5y2tA-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU D 255
PHE D 363
LEU D 330
ILE D 341
MET D 348
LEU D 452
 None
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
None
 1.45A 5y2tA-3dzuD:
36.6		 5y2tA-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 282
GLY D 284
CYH D 285
GLN D 286
LEU D 330
MET D 364
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
 0.89A 5y2tA-3dzuD:
36.6		 5y2tA-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 ILE D 281
ILE D 326
TYR D 327
LEU D 330
ILE D 341
MET D 348
HIS D 449
 PLB  D 701 (-4.6A)
PLB  D 701 ( 4.5A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
None
 0.76A 5y2tB-3dzuD:
34.2		 5y2tB-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 LEU D 255
ARG D 280
ILE D 281
GLN D 286
ILE D 326
LEU D 330
ILE D 341
MET D 348
 None
None
PLB  D 701 (-4.6A)
None
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
 0.67A 5y2tB-3dzuD:
34.2		 5y2tB-3dzuD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 LEU D 255
ARG D 280
ILE D 281
ILE D 326
LEU D 330
ILE D 341
MET D 348
HIS D 449
 None
None
PLB  D 701 (-4.6A)
PLB  D 701 ( 4.5A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
None
 0.76A 5y2tB-3dzuD:
34.2		 5y2tB-3dzuD:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		10 / 12 LEU D 255
ARG D 280
ILE D 281
GLY D 284
LEU D 330
VAL D 339
ILE D 341
MET D 348
MET D 364
LEU D 469
 None
None
PLB  D 701 (-4.6A)
PLB  D 701 (-3.3A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
 0.56A 5ycnA-3dzuD:
38.1		 5ycnA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 LEU D 255
ARG D 280
ILE D 281
LEU D 330
VAL D 339
MET D 348
LEU D 469
 None
None
PLB  D 701 (-4.6A)
PLB  D 701 ( 4.1A)
None
PLB  D 701 ( 4.7A)
None
 1.46A 5ycnA-3dzuD:
38.1		 5ycnA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU D 255
ILE D 281
VAL D 339
ILE D 341
MET D 348
LEU D 465
 None
PLB  D 701 (-4.6A)
None
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
None
 1.09A 5ycnA-3dzuD:
38.1		 5ycnA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 TYR D 327
LEU D 330
VAL D 339
ILE D 341
MET D 348
MET D 364
LEU D 469
 None
PLB  D 701 ( 4.1A)
None
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.7A)
PLB  D 701 ( 4.8A)
None
 0.75A 5ycnA-3dzuD:
38.1		 5ycnA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 0.96A 5ycpA-3dzuD:
38.1		 5ycpA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
SER D 289
LEU D 330
ILE D 341
MET D 364
LEU D 469
TYR D 473
 None
PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
None
None
 0.73A 5ycpA-3dzuD:
38.1		 5ycpA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 SER D 289
LEU D 330
ILE D 341
MET D 364
HIS D 449
LEU D 469
TYR D 473
 PLB  D 701 ( 3.9A)
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
None
None
None
 0.72A 5ycpA-3dzuD:
38.1		 5ycpA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 TYR D 327
LEU D 330
ILE D 341
MET D 364
HIS D 449
LEU D 469
TYR D 473
 None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
None
None
None
 0.88A 5ycpA-3dzuD:
38.1		 5ycpA-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		3 / 3 GLY D 284
VAL D 339
MET D 348
 PLB  D 701 (-3.3A)
None
PLB  D 701 ( 4.7A)
 0.23A 5ycpA-3dzuD:
38.1		 5ycpA-3dzuD:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 GLY A 154
ASN A 185
THR A 162
TYR A 169
TYR A 147
 None
 1.41A 5yf0A-3dzuA:
undetectable		 5yf0A-3dzuA:
20.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.60A 5z12B-3dzuA:
33.8		 5z12B-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 GLN A 275
ILE A 345
HIS A 435
 9CR  A7223 (-4.6A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-4.3A)
 0.38A 5z12B-3dzuA:
33.8		 5z12B-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.70A 5z12C-3dzuA:
33.0		 5z12C-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 428
CYH A 432
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
None
9CR  A7223 (-3.8A)
 1.45A 6a5yD-3dzuA:
34.1		 6a5yD-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.68A 6a5yD-3dzuA:
34.1		 6a5yD-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ALA A 271
ALA A 272
GLN A 275
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ILE A 345
CYH A 432
LEU A 436
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.53A 6a5zD-3dzuA:
34.2		 6a5zD-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ALA A 272
GLN A 275
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ALA A 327
CYH A 432
LEU A 436
 9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.55A 6a5zD-3dzuA:
34.2		 6a5zD-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
ILE A 310
PHE A 313
ARG A 316
ILE A 345
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.50A 6a5zD-3dzuA:
34.2		 6a5zD-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.68A 6a5zL-3dzuA:
34.0		 6a5zL-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.62A 6a60D-3dzuA:
34.4		 6a60D-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLY D 284
CYH D 285
TYR D 473
LEU D 469
HIS D 449
 PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
None
None
 1.45A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
CYH D 285
GLN D 286
HIS D 323
TYR D 327
 None
PLB  D 701 (-3.2A)
None
None
None
 1.16A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
CYH D 285
HIS D 323
TYR D 327
HIS D 449
 None
PLB  D 701 (-3.2A)
None
None
None
 1.13A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
GLN D 286
HIS D 323
TYR D 327
TYR D 473
 None
 1.14A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
GLY D 284
CYH D 285
GLN D 286
TYR D 327
LEU D 330
MET D 364
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
 0.91A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 PHE D 282
GLY D 284
CYH D 285
TYR D 327
LEU D 330
MET D 364
HIS D 449
 None
PLB  D 701 (-3.3A)
PLB  D 701 (-3.2A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 ( 4.8A)
None
 1.00A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		9 / 12 PHE D 282
GLY D 284
GLN D 286
SER D 289
TYR D 327
LEU D 330
ILE D 341
MET D 364
TYR D 473
 None
PLB  D 701 (-3.3A)
None
PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
None
 0.68A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		9 / 12 PHE D 282
GLY D 284
SER D 289
TYR D 327
LEU D 330
ILE D 341
MET D 364
HIS D 449
TYR D 473
 None
PLB  D 701 (-3.3A)
PLB  D 701 ( 3.9A)
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
PLB  D 701 ( 4.8A)
None
None
 0.85A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 PHE D 282
HIS D 323
TYR D 327
HIS D 449
TYR D 473
 None
 1.23A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 PHE D 363
TYR D 327
LEU D 330
ILE D 341
HIS D 449
TYR D 473
 None
None
PLB  D 701 ( 4.1A)
PLB  D 701 (-3.6A)
None
None
 1.49A 6md4A-3dzuD:
36.8		 6md4A-3dzuD:
100.00