SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e02'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
3 / 3 GLU A 258
HIS A  49
HIS A  51
ZN  A 311 (-2.5A)
ZN  A 311 (-3.3A)
ZN  A 311 (-3.4A)
0.65A 1oe2A-3e02A:
undetectable
1oe2A-3e02A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_2
(ORPHAN NUCLEAR
RECEPTOR PXR)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
4 / 5 PHE A 151
LEU A  94
MET A 158
LEU A 196
None
EDO  A 320 (-4.5A)
None
None
1.16A 1skxA-3e02A:
undetectable
1skxA-3e02A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
4 / 7 ASP A 294
THR A 292
ILE A   8
ASN A 252
None
1.26A 2jc9A-3e02A:
undetectable
2jc9A-3e02A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
5 / 12 ALA A  99
LEU A  94
ARG A 156
GLY A  89
HIS A  51
None
EDO  A 320 (-4.5A)
EDO  A 320 (-4.5A)
None
ZN  A 311 (-3.4A)
1.13A 2yjaB-3e02A:
undetectable
2yjaB-3e02A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
4 / 7 GLY A  37
ALA A  45
ALA A  80
VAL A 276
None
0.74A 3a2qA-3e02A:
undetectable
3a2qA-3e02A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
5 / 12 PHE A 118
GLY A  89
GLY A  91
HIS A  49
SER A  16
EDO  A 313 (-4.9A)
None
EDO  A 317 ( 3.9A)
ZN  A 311 (-3.3A)
None
1.15A 3dlcA-3e02A:
undetectable
3dlcA-3e02A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
3 / 3 ASP A  63
LEU A  66
GLN A  73
None
0.76A 3g4lA-3e02A:
undetectable
3g4lA-3e02A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
4 / 8 PHE A 151
PHE A 184
CYH A 172
MET A 113
None
1.07A 3ko0B-3e02A:
undetectable
3ko0J-3e02A:
undetectable
3ko0B-3e02A:
15.89
3ko0J-3e02A:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
5 / 12 LEU A 196
CYH A 172
TYR A 179
LEU A 223
LEU A 181
None
1.17A 3okxA-3e02A:
undetectable
3okxA-3e02A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
5 / 12 LEU A 196
HIS A 215
TYR A 179
LEU A 223
LEU A 181
None
1.28A 3okxA-3e02A:
undetectable
3okxA-3e02A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
5 / 12 LEU A 196
CYH A 172
TYR A 179
LEU A 223
LEU A 181
None
1.18A 3okxB-3e02A:
undetectable
3okxB-3e02A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
5 / 12 LEU A 196
HIS A 215
TYR A 179
LEU A 223
LEU A 181
None
1.33A 3okxB-3e02A:
undetectable
3okxB-3e02A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
5 / 12 ALA A  99
LEU A  94
ARG A 156
GLY A  89
HIS A  51
None
EDO  A 320 (-4.5A)
EDO  A 320 (-4.5A)
None
ZN  A 311 (-3.4A)
1.12A 3olsA-3e02A:
undetectable
3olsA-3e02A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
5 / 12 ALA A  99
LEU A  94
ARG A 156
GLY A  89
HIS A  51
None
EDO  A 320 (-4.5A)
EDO  A 320 (-4.5A)
None
ZN  A 311 (-3.4A)
1.10A 3q95A-3e02A:
undetectable
3q95A-3e02A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
5 / 11 ALA A  99
LEU A  94
ARG A 156
GLY A  89
HIS A  51
None
EDO  A 320 (-4.5A)
EDO  A 320 (-4.5A)
None
ZN  A 311 (-3.4A)
1.12A 3uudA-3e02A:
undetectable
3uudA-3e02A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ACTA908_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
4 / 4 MET A 245
SER A 246
LEU A 213
VAL A 232
None
1.29A 3vlnA-3e02A:
0.0
3vlnA-3e02A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
3 / 3 ARG A 280
ARG A 277
ILE A 290
None
EDO  A 321 (-4.2A)
None
0.80A 4b7qA-3e02A:
undetectable
4b7qA-3e02A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
3 / 3 ARG A 280
ARG A 281
ILE A 290
None
EDO  A 321 (-3.1A)
None
0.91A 4b7qA-3e02A:
undetectable
4b7qA-3e02A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
3 / 3 ARG A 280
ARG A 277
ILE A 290
None
EDO  A 321 (-4.2A)
None
0.84A 4b7qC-3e02A:
undetectable
4b7qC-3e02A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
5 / 12 ALA A  99
LEU A  94
ARG A 156
GLY A  89
HIS A  51
None
EDO  A 320 (-4.5A)
EDO  A 320 (-4.5A)
None
ZN  A 311 (-3.4A)
1.10A 4pxmA-3e02A:
undetectable
4pxmA-3e02A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
4 / 7 GLU A  36
GLU A 274
ALA A 269
TYR A  25
EDO  A 316 ( 4.7A)
EDO  A 312 (-4.6A)
None
None
0.90A 4zz8A-3e02A:
undetectable
4zz8A-3e02A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
5 / 11 ALA A  99
LEU A  94
ARG A 156
GLY A  89
HIS A  51
None
EDO  A 320 (-4.5A)
EDO  A 320 (-4.5A)
None
ZN  A 311 (-3.4A)
1.13A 5dxbB-3e02A:
undetectable
5dxbB-3e02A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
5 / 11 ALA A  99
LEU A  94
ARG A 156
GLY A  89
HIS A  51
None
EDO  A 320 (-4.5A)
EDO  A 320 (-4.5A)
None
ZN  A 311 (-3.4A)
1.11A 5dxgB-3e02A:
undetectable
5dxgB-3e02A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
4 / 6 SER A  16
HIS A  51
MET A  92
LEU A 147
None
ZN  A 311 (-3.4A)
None
None
1.18A 5dzke-3e02A:
2.8
5dzks-3e02A:
undetectable
5dzke-3e02A:
23.32
5dzks-3e02A:
0.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
4 / 7 SER A 164
THR A 166
PHE A 168
VAL A 108
None
1.09A 5vkqA-3e02A:
undetectable
5vkqB-3e02A:
undetectable
5vkqA-3e02A:
11.01
5vkqB-3e02A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
4 / 8 SER A 164
THR A 166
PHE A 168
VAL A 108
None
1.07A 5vkqB-3e02A:
undetectable
5vkqC-3e02A:
undetectable
5vkqB-3e02A:
11.01
5vkqC-3e02A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
4 / 7 SER A 164
THR A 166
PHE A 168
VAL A 108
None
1.09A 5vkqC-3e02A:
undetectable
5vkqD-3e02A:
undetectable
5vkqC-3e02A:
11.01
5vkqD-3e02A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
4 / 5 ARG A 156
MET A 158
THR A 159
LEU A 189
EDO  A 320 (-4.5A)
None
None
None
1.15A 5z86J-3e02A:
undetectable
5z86J-3e02A:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_B_ACTB207_0
(DUF1778
DOMAIN-CONTAINING
PROTEIN
N-ACETYLTRANSFERASE)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
4 / 6 LEU A  26
THR A  14
GLY A  15
ARG A  53
None
None
ZN  A 311 ( 4.8A)
None
1.30A 6gtqB-3e02A:
0.0
6gtqD-3e02A:
undetectable
6gtqB-3e02A:
21.54
6gtqD-3e02A:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans)
4 / 5 ARG A 156
MET A 158
THR A 159
LEU A 189
EDO  A 320 (-4.5A)
None
None
None
1.36A 6nknW-3e02A:
undetectable
6nknW-3e02A:
10.93