SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e03'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 12 LEU A  21
GLY A  31
GLY A  63
ALA A  24
LEU A  25
None
0.93A 1bx4A-3e03A:
5.9
1bx4A-3e03A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.49A 1gtfB-3e03A:
undetectable
1gtfC-3e03A:
undetectable
1gtfB-3e03A:
15.33
1gtfC-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.50A 1gtfE-3e03A:
undetectable
1gtfF-3e03A:
undetectable
1gtfE-3e03A:
15.33
1gtfF-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.50A 1gtfF-3e03A:
undetectable
1gtfG-3e03A:
undetectable
1gtfF-3e03A:
15.33
1gtfG-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 8 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.48A 1gtnA-3e03A:
undetectable
1gtnB-3e03A:
undetectable
1gtnA-3e03A:
15.33
1gtnB-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.49A 1gtnG-3e03A:
undetectable
1gtnH-3e03A:
undetectable
1gtnG-3e03A:
15.33
1gtnH-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
4 / 4 HIS A 237
ALA A 180
PHE A 183
GLY A 184
None
1.42A 1mj2B-3e03A:
undetectable
1mj2B-3e03A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
4 / 4 HIS A 237
ALA A 180
PHE A 183
GLY A 184
None
1.39A 1mj2D-3e03A:
undetectable
1mj2D-3e03A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
4 / 4 HIS A 237
ALA A 180
PHE A 183
GLY A 184
None
1.40A 1mjoD-3e03A:
undetectable
1mjoD-3e03A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
3 / 3 VAL A  58
ALA A  55
HIS A  52
None
0.72A 1q23C-3e03A:
undetectable
1q23C-3e03A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
4 / 4 ALA A  54
VAL A  58
ALA A  55
HIS A  52
None
0.99A 1q23A-3e03A:
undetectable
1q23A-3e03A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
4 / 4 ALA A  54
VAL A  58
ALA A  55
HIS A  52
None
0.90A 1q23F-3e03A:
undetectable
1q23F-3e03A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
3 / 3 VAL A  58
ALA A  55
HIS A  52
None
0.72A 1q23H-3e03A:
undetectable
1q23H-3e03A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
4 / 4 ALA A  54
VAL A  58
ALA A  55
HIS A  52
None
0.98A 1q23K-3e03A:
undetectable
1q23K-3e03A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
3 / 3 VAL A  58
ALA A  55
HIS A  52
None
0.72A 1q23L-3e03A:
undetectable
1q23L-3e03A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 11 HIS A  52
ASN A  59
VAL A  58
ILE A  51
ALA A  15
None
1.28A 2iyfA-3e03A:
4.9
2iyfA-3e03A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_1
(PROTEASE)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 12 GLY A 125
ASP A  71
GLY A  14
VAL A  82
VAL A  78
None
0.83A 2nnkA-3e03A:
undetectable
2nnkA-3e03A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 12 GLY A 125
ASP A  71
GLY A  14
VAL A  82
VAL A  78
None
0.88A 2nnkB-3e03A:
undetectable
2nnkB-3e03A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 11 LEU A 193
ILE A 242
ALA A 149
LEU A 272
ASP A 269
None
1.16A 2q72A-3e03A:
undetectable
2q72A-3e03A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 11 LEU A 193
ILE A 242
ALA A 149
LEU A 272
ASP A 269
None
1.18A 2qjuA-3e03A:
undetectable
2qjuA-3e03A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
4 / 5 SER A 100
ASP A 269
ASP A 244
ILE A 242
None
1.37A 3uj7B-3e03A:
5.8
3uj7B-3e03A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
4 / 5 LEU A 134
PRO A 135
LEU A 137
ILE A 145
None
0.88A 4klrA-3e03A:
3.0
4klrA-3e03A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 12 ASN A  98
ILE A 102
TYR A 165
ARG A  73
LEU A 117
None
1.47A 4kosA-3e03A:
0.7
4kosA-3e03A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 11 HIS A  52
ASN A  59
VAL A  58
ILE A  51
ALA A  15
None
1.28A 4m83A-3e03A:
undetectable
4m83A-3e03A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_B_ERYB501_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 11 HIS A  52
ASN A  59
VAL A  58
ILE A  51
ALA A  15
None
1.28A 4m83B-3e03A:
undetectable
4m83B-3e03A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ARF_A_SAMA1002_0
(N-LYSINE
METHYLTRANSFERASE
SMYD2)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 12 ASN A 122
ALA A 101
HIS A 162
TYR A 165
PHE A 271
None
None
CA  A   1 (-3.7A)
None
None
1.50A 5arfA-3e03A:
undetectable
5arfA-3e03A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 12 ALA A  28
THR A   9
GLY A  65
GLY A  63
ALA A  56
None
0.96A 5c0oG-3e03A:
6.1
5c0oG-3e03A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.49A 5eeuA-3e03A:
undetectable
5eeuB-3e03A:
undetectable
5eeuA-3e03A:
15.33
5eeuB-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.49A 5eeuE-3e03A:
undetectable
5eeuF-3e03A:
undetectable
5eeuE-3e03A:
15.33
5eeuF-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.49A 5eevE-3e03A:
undetectable
5eevF-3e03A:
undetectable
5eevE-3e03A:
15.33
5eevF-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.49A 5eewE-3e03A:
undetectable
5eewF-3e03A:
undetectable
5eewE-3e03A:
15.33
5eewF-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.49A 5eexE-3e03A:
undetectable
5eexF-3e03A:
undetectable
5eexE-3e03A:
15.33
5eexF-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 ALA A 130
THR A 147
THR A 176
ILE A 190
SER A 126
None
1.50A 5eexQ-3e03A:
undetectable
5eexR-3e03A:
undetectable
5eexQ-3e03A:
15.33
5eexR-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.49A 5eeyE-3e03A:
undetectable
5eeyF-3e03A:
undetectable
5eeyE-3e03A:
15.33
5eeyF-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 ALA A 130
THR A 147
THR A 176
ILE A 190
SER A 126
None
1.50A 5eeyQ-3e03A:
undetectable
5eeyR-3e03A:
undetectable
5eeyQ-3e03A:
15.33
5eeyR-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.50A 5eezE-3e03A:
undetectable
5eezF-3e03A:
undetectable
5eezE-3e03A:
15.33
5eezF-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.50A 5ef0E-3e03A:
undetectable
5ef0F-3e03A:
undetectable
5ef0E-3e03A:
15.33
5ef0F-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.50A 5ef1E-3e03A:
undetectable
5ef1F-3e03A:
undetectable
5ef1E-3e03A:
15.33
5ef1F-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 9 SER A 126
ALA A 130
THR A 147
THR A 176
ILE A 190
None
1.50A 5ef2E-3e03A:
undetectable
5ef2F-3e03A:
undetectable
5ef2E-3e03A:
15.33
5ef2F-3e03A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
5 / 12 PHE A 236
ALA A 123
THR A  13
LEU A  95
ILE A  94
None
1.23A 6aybA-3e03A:
undetectable
6aybA-3e03A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)
3e03 SHORT CHAIN
DEHYDROGENASE

(Xanthomonas
campestris)
4 / 6 SER A  40
ALA A  54
SER A  53
ALA A  38
None
0.94A 6bocA-3e03A:
undetectable
6bocB-3e03A:
undetectable
6bocC-3e03A:
undetectable
6bocD-3e03A:
undetectable
6bocA-3e03A:
7.14
6bocB-3e03A:
7.14
6bocC-3e03A:
7.14
6bocD-3e03A:
7.14