SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e0f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 5 HIS A  17
HIS A  85
HIS A 202
ASP A 260
 FE  A 303 (-3.3A)
FE  A 302 ( 3.2A)
FE  A 302 (-3.6A)
FE  A 303 ( 2.6A)
 0.63A 1e9yB-3e0fA:
3.3		 1e9yB-3e0fA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		5 / 6 HIS A  17
HIS A  19
HIS A  85
HIS A 202
ASP A 260
 FE  A 303 (-3.3A)
FE  A 303 ( 3.5A)
FE  A 302 ( 3.2A)
FE  A 302 (-3.6A)
FE  A 303 ( 2.6A)
 0.55A 1fweC-3e0fA:
2.6		 1fweC-3e0fA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 ASP A  24
HIS A  19
HIS A  49
 ZN  A 301 ( 2.2A)
FE  A 303 ( 3.5A)
ZN  A 301 ( 3.3A)
 0.64A 1oe1A-3e0fA:
undetectable		 1oe1A-3e0fA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 ASP A  24
HIS A  19
HIS A  49
 ZN  A 301 ( 2.2A)
FE  A 303 ( 3.5A)
ZN  A 301 ( 3.3A)
 0.64A 1oe3A-3e0fA:
undetectable		 1oe3A-3e0fA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		5 / 11 GLY A  25
HIS A 262
GLY A 144
HIS A 147
VAL A  21
 None
ZN  A 301 ( 3.5A)
PO4  A 305 ( 3.9A)
None
None
 1.12A 1pg2A-3e0fA:
undetectable		 1pg2A-3e0fA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 4 HIS A  49
GLU A  74
HIS A  19
HIS A 262
 ZN  A 301 ( 3.3A)
FE  A 303 (-2.5A)
FE  A 303 ( 3.5A)
ZN  A 301 ( 3.5A)
 1.18A 1utzB-3e0fA:
undetectable		 1utzB-3e0fA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 4 GLY A 271
SER A 259
VAL A  44
LEU A  39
 None
 1.10A 1yajB-3e0fA:
undetectable		 1yajB-3e0fA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 4 HIS A  49
GLU A  74
HIS A  19
HIS A 262
 ZN  A 301 ( 3.3A)
FE  A 303 (-2.5A)
FE  A 303 ( 3.5A)
ZN  A 301 ( 3.5A)
 1.15A 2ow9B-3e0fA:
undetectable		 2ow9B-3e0fA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 SER A  62
HIS A  42
ASP A 278
 None
 0.70A 2oxtA-3e0fA:
undetectable		 2oxtA-3e0fA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 4 HIS A  49
GLU A  74
HIS A  19
HIS A 262
 ZN  A 301 ( 3.3A)
FE  A 303 (-2.5A)
FE  A 303 ( 3.5A)
ZN  A 301 ( 3.5A)
 1.17A 2ozrC-3e0fA:
undetectable		 2ozrC-3e0fA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 213
LEU A 212
GLY A 204
GLN A 240
MET A 221
 None
 1.41A 2q7lA-3e0fA:
undetectable		 2q7lA-3e0fA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		5 / 10 VAL A  84
VAL A  78
ASP A 224
ILE A 188
VAL A 187
 None
None
ACT  A 306 (-2.9A)
None
None
 1.29A 2qboA-3e0fA:
undetectable		 2qboA-3e0fA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 ASP A  24
HIS A  19
HIS A  49
 ZN  A 301 ( 2.2A)
FE  A 303 ( 3.5A)
ZN  A 301 ( 3.3A)
 0.66A 2xxgA-3e0fA:
undetectable		 2xxgA-3e0fA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 ASP A  24
HIS A  19
HIS A  49
 ZN  A 301 ( 2.2A)
FE  A 303 ( 3.5A)
ZN  A 301 ( 3.3A)
 0.69A 2xxgC-3e0fA:
undetectable		 2xxgC-3e0fA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y4N_B_PACB503_0
(PHENYLACETATE-COENZY
ME A LIGASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 4 SER A 259
GLY A  25
GLY A 265
LYS A 266
 None
None
None
PO4  A 304 (-2.9A)
 1.01A 2y4nB-3e0fA:
0.1		 2y4nB-3e0fA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		5 / 12 ASP A  15
ASP A 260
LEU A  32
GLY A 263
HIS A 262
 None
FE  A 303 ( 2.6A)
None
None
ZN  A 301 ( 3.5A)
 1.45A 3ce6B-3e0fA:
undetectable		 3ce6B-3e0fA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 5 HIS A  17
HIS A  85
HIS A 202
ASP A 260
 FE  A 303 (-3.3A)
FE  A 302 ( 3.2A)
FE  A 302 (-3.6A)
FE  A 303 ( 2.6A)
 0.56A 4h9mA-3e0fA:
6.6		 4h9mA-3e0fA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 7 ASP A 260
HIS A 262
PRO A 146
GLU A  74
 FE  A 303 ( 2.6A)
ZN  A 301 ( 3.5A)
PO4  A 305 ( 4.8A)
FE  A 303 (-2.5A)
 1.09A 4hvrA-3e0fA:
undetectable		 4hvrA-3e0fA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 8 SER A 259
ASP A  15
GLU A 230
THR A  20
 None
 0.97A 4lnwA-3e0fA:
undetectable		 4lnwA-3e0fA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 6 PHE A  89
HIS A  19
HIS A  17
GLU A  74
 None
FE  A 303 ( 3.5A)
FE  A 303 (-3.3A)
FE  A 303 (-2.5A)
 0.91A 4pahA-3e0fA:
undetectable		 4pahA-3e0fA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 PRO A  29
LEU A  32
HIS A  17
 None
None
FE  A 303 (-3.3A)
 0.69A 4pevA-3e0fA:
undetectable		 4pevA-3e0fA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		5 / 9 LEU A 213
GLY A 204
VAL A  84
SER A  83
VAL A  82
 None
 1.11A 4qd3A-3e0fA:
undetectable		 4qd3A-3e0fA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		5 / 6 HIS A  17
HIS A  19
HIS A  85
HIS A 202
ASP A 260
 FE  A 303 (-3.3A)
FE  A 303 ( 3.5A)
FE  A 302 ( 3.2A)
FE  A 302 (-3.6A)
FE  A 303 ( 2.6A)
 0.54A 4ubpC-3e0fA:
2.2		 4ubpC-3e0fA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		5 / 12 ASP A  50
HIS A  49
PHE A 102
ILE A  75
ALA A  88
 None
ZN  A 301 ( 3.3A)
None
None
None
 1.42A 4wh5A-3e0fA:
0.9		 4wh5A-3e0fA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 ASP A  56
GLU A  63
SER A  99
 None
 0.86A 5bw4B-3e0fA:
undetectable		 5bw4B-3e0fA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 GLU A 230
HIS A  17
ASP A 205
 None
FE  A 303 (-3.3A)
None
 0.81A 5c0oG-3e0fA:
undetectable		 5c0oG-3e0fA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		5 / 12 ASP A  15
ALA A  58
GLY A  72
LEU A  71
GLY A  25
 None
 0.96A 5i73A-3e0fA:
undetectable		 5i73A-3e0fA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 6 HIS A 202
HIS A  19
HIS A 262
LEU A  87
 FE  A 302 (-3.6A)
FE  A 303 ( 3.5A)
ZN  A 301 ( 3.5A)
None
 1.09A 5nelB-3e0fA:
3.8
5nelC-3e0fA:
3.5		 5nelB-3e0fA:
22.26
5nelC-3e0fA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 6 HIS A 233
HIS A  19
HIS A 262
LEU A  87
 None
FE  A 303 ( 3.5A)
ZN  A 301 ( 3.5A)
None
 1.06A 5nelB-3e0fA:
3.8
5nelC-3e0fA:
3.5		 5nelB-3e0fA:
22.26
5nelC-3e0fA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 7 GLY A 144
ASP A 150
HIS A 262
ASP A  24
 PO4  A 305 ( 3.9A)
None
ZN  A 301 ( 3.5A)
ZN  A 301 ( 2.2A)
 0.98A 5nnwD-3e0fA:
undetectable		 5nnwD-3e0fA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 7 GLY A 144
ASP A 150
HIS A 262
ASP A  24
 PO4  A 305 ( 3.9A)
None
ZN  A 301 ( 3.5A)
ZN  A 301 ( 2.2A)
 0.89A 5no9D-3e0fA:
undetectable		 5no9D-3e0fA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 HIS A  49
ASP A  24
HIS A 262
 ZN  A 301 ( 3.3A)
ZN  A 301 ( 2.2A)
ZN  A 301 ( 3.5A)
 0.79A 5oexA-3e0fA:
undetectable		 5oexA-3e0fA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 HIS A 262
ASP A  24
HIS A  49
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 2.2A)
ZN  A 301 ( 3.3A)
 0.37A 5oexA-3e0fA:
undetectable		 5oexA-3e0fA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 HIS A  49
ASP A  24
HIS A 262
 ZN  A 301 ( 3.3A)
ZN  A 301 ( 2.2A)
ZN  A 301 ( 3.5A)
 0.79A 5oexB-3e0fA:
undetectable		 5oexB-3e0fA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 HIS A 262
ASP A  24
HIS A  49
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 2.2A)
ZN  A 301 ( 3.3A)
 0.33A 5oexB-3e0fA:
undetectable		 5oexB-3e0fA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 HIS A  49
ASP A  24
HIS A 262
 ZN  A 301 ( 3.3A)
ZN  A 301 ( 2.2A)
ZN  A 301 ( 3.5A)
 0.74A 5oexC-3e0fA:
undetectable		 5oexC-3e0fA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 HIS A 262
ASP A  24
HIS A  49
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 2.2A)
ZN  A 301 ( 3.3A)
 0.29A 5oexC-3e0fA:
undetectable		 5oexC-3e0fA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 HIS A  49
ASP A  24
HIS A 262
 ZN  A 301 ( 3.3A)
ZN  A 301 ( 2.2A)
ZN  A 301 ( 3.5A)
 0.75A 5oexD-3e0fA:
undetectable		 5oexD-3e0fA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		3 / 3 HIS A 262
ASP A  24
HIS A  49
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 2.2A)
ZN  A 301 ( 3.3A)
 0.29A 5oexD-3e0fA:
undetectable		 5oexD-3e0fA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 274
LEU A 270
ILE A  46
LEU A  32
LEU A  87
 None
 1.23A 5toaB-3e0fA:
undetectable		 5toaB-3e0fA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 5 GLY A 235
ASN A 236
ASP A 205
ARG A 234
 None
 1.31A 6dwdB-3e0fA:
undetectable
6dwdD-3e0fA:
undetectable		 6dwdB-3e0fA:
19.02
6dwdD-3e0fA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE
(Bifidobacterium
adolescentis) 		4 / 5 ARG A 234
GLY A 235
ASN A 236
ASP A 205
 None
 1.32A 6dwjB-3e0fA:
undetectable
6dwjD-3e0fA:
undetectable		 6dwjB-3e0fA:
19.02
6dwjD-3e0fA:
19.02