SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e0j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)
3e0j DNA POLYMERASE
SUBUNIT DELTA-3

(Homo
sapiens)
4 / 8 GLU B  82
LEU B  57
ARG B  49
LEU B 114
None
0.77A 1ereE-3e0jB:
undetectable
1ereE-3e0jB:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)
3e0j DNA POLYMERASE
SUBUNIT DELTA-3

(Homo
sapiens)
4 / 8 GLU B  82
LEU B  57
ARG B  49
LEU B 114
None
0.78A 1ereF-3e0jB:
undetectable
1ereF-3e0jB:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 7 THR A 320
VAL A 294
VAL A 276
ASP A 280
None
1.06A 1t85A-3e0jA:
undetectable
1t85A-3e0jA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 7 THR A 320
VAL A 294
VAL A 276
ASP A 280
None
1.05A 1t87A-3e0jA:
undetectable
1t87A-3e0jA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2
DNA POLYMERASE
SUBUNIT DELTA-3

(Homo
sapiens)
5 / 12 ALA A 437
LEU A 197
GLN A 216
LEU A 226
VAL B  77
None
1.26A 1u72A-3e0jA:
undetectable
1u72A-3e0jA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 7 THR A 320
LEU A 327
VAL A 294
VAL A 276
ASP A 280
None
1.37A 1yrcA-3e0jA:
undetectable
1yrcA-3e0jA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 7 THR A 320
LEU A 327
VAL A 294
VAL A 276
ASP A 280
None
1.36A 1yrdA-3e0jA:
undetectable
1yrdA-3e0jA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2
DNA POLYMERASE
SUBUNIT DELTA-3

(Homo
sapiens;
Homo
sapiens)
4 / 8 LEU A 439
ARG A  26
SER B  97
GLY A 224
None
0.88A 2qd5A-3e0jA:
undetectable
2qd5A-3e0jA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 LEU A 133
HIS A  72
TRP A  73
ASP A 149
None
0.88A 2y69C-3e0jA:
undetectable
2y69N-3e0jA:
undetectable
2y69P-3e0jA:
undetectable
2y69C-3e0jA:
18.12
2y69N-3e0jA:
22.05
2y69P-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2
DNA POLYMERASE
SUBUNIT DELTA-3

(Homo
sapiens)
5 / 12 VAL A  27
SER B 130
VAL A 241
LEU A 439
LEU A 442
None
1.12A 2zlcA-3e0jA:
undetectable
2zlcA-3e0jA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_1
(CATECHOL
O-METHYLTRANSFERASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
3 / 3 SER A 234
GLU A   4
ASP A 193
None
0.85A 2zthA-3e0jA:
undetectable
2zthA-3e0jA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 7 THR A 320
LEU A 327
VAL A 294
VAL A 276
ASP A 280
None
1.35A 2zwtA-3e0jA:
undetectable
2zwtA-3e0jA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 7 THR A 320
LEU A 327
VAL A 294
VAL A 276
ASP A 280
None
1.35A 2zwuA-3e0jA:
undetectable
2zwuA-3e0jA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.96A 3ablA-3e0jA:
undetectable
3ablC-3e0jA:
undetectable
3ablP-3e0jA:
undetectable
3ablA-3e0jA:
22.05
3ablC-3e0jA:
18.12
3ablP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 LEU A 133
HIS A  72
TRP A  73
ASP A 149
None
0.90A 3ablC-3e0jA:
undetectable
3ablN-3e0jA:
undetectable
3ablP-3e0jA:
undetectable
3ablC-3e0jA:
18.12
3ablN-3e0jA:
22.05
3ablP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.90A 3abmA-3e0jA:
undetectable
3abmC-3e0jA:
undetectable
3abmP-3e0jA:
undetectable
3abmA-3e0jA:
22.05
3abmC-3e0jA:
18.12
3abmP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 LEU A 133
HIS A  72
TRP A  73
ASP A 149
None
0.92A 3asnC-3e0jA:
undetectable
3asnN-3e0jA:
undetectable
3asnP-3e0jA:
undetectable
3asnC-3e0jA:
18.12
3asnN-3e0jA:
22.05
3asnP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.93A 3asoA-3e0jA:
undetectable
3asoC-3e0jA:
undetectable
3asoP-3e0jA:
undetectable
3asoA-3e0jA:
22.05
3asoC-3e0jA:
18.12
3asoP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 LEU A 133
HIS A  72
TRP A  73
ASP A 149
None
0.92A 3asoC-3e0jA:
undetectable
3asoN-3e0jA:
0.7
3asoP-3e0jA:
undetectable
3asoC-3e0jA:
18.12
3asoN-3e0jA:
22.05
3asoP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 PHE A 341
VAL A 423
LEU A 369
PRO A 399
None
1.14A 3bgdB-3e0jA:
undetectable
3bgdB-3e0jA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 7 THR A 320
LEU A 327
VAL A 294
VAL A 276
ASP A 280
None
1.40A 3fwfA-3e0jA:
undetectable
3fwfA-3e0jA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 7 THR A 320
LEU A 327
VAL A 294
VAL A 276
ASP A 280
None
1.38A 3fwfB-3e0jA:
undetectable
3fwfB-3e0jA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 7 THR A 320
LEU A 327
VAL A 294
VAL A 276
ASP A 280
None
1.39A 3fwjA-3e0jA:
undetectable
3fwjA-3e0jA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 12 LEU A 283
ASP A 300
LEU A 204
LEU A 202
GLY A 201
None
1.27A 3g1uC-3e0jA:
undetectable
3g1uC-3e0jA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 12 LEU A 283
ASP A 300
LEU A 204
LEU A 202
GLY A 201
None
1.23A 3g1uD-3e0jA:
undetectable
3g1uD-3e0jA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 12 LEU A 283
ASP A 300
LEU A 204
LEU A 202
GLY A 201
None
1.30A 3glqA-3e0jA:
undetectable
3glqA-3e0jA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 12 LEU A 283
ASP A 300
LEU A 204
LEU A 202
GLY A 201
None
1.30A 3glqB-3e0jA:
undetectable
3glqB-3e0jA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 7 VAL A 328
ILE A 336
TYR A  32
THR A  31
None
0.95A 3gssA-3e0jA:
undetectable
3gssA-3e0jA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 7 VAL A 328
ILE A 336
TYR A  32
THR A  31
None
0.91A 3gssB-3e0jA:
undetectable
3gssB-3e0jA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 6 LEU A 365
GLU A 366
LYS A 413
LEU A 425
None
0.71A 3h5gA-3e0jA:
undetectable
3h5gC-3e0jA:
undetectable
3h5gA-3e0jA:
4.83
3h5gC-3e0jA:
4.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
3 / 3 ASP A 193
ARG A 443
ARG A   9
None
0.96A 3k37A-3e0jA:
undetectable
3k37A-3e0jA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 7 THR A 320
LEU A 327
VAL A 294
VAL A 276
ASP A 280
None
1.39A 3l63A-3e0jA:
undetectable
3l63A-3e0jA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 12 LEU A  97
VAL A  93
TYR A 176
PHE A 171
LEU A 144
None
1.30A 3megA-3e0jA:
undetectable
3megA-3e0jA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 PHE A 395
ARG A  57
ASP A 391
PHE A 393
None
1.07A 3mjrD-3e0jA:
undetectable
3mjrD-3e0jA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
3 / 3 SER A 356
SER A 357
HIS A 128
None
0.64A 3mzeA-3e0jA:
undetectable
3mzeA-3e0jA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 12 LEU A 283
ASP A 300
LEU A 204
LEU A 202
GLY A 201
None
1.27A 3n58A-3e0jA:
undetectable
3n58A-3e0jA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.91A 3wg7A-3e0jA:
undetectable
3wg7C-3e0jA:
undetectable
3wg7P-3e0jA:
undetectable
3wg7A-3e0jA:
22.05
3wg7C-3e0jA:
18.12
3wg7P-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 LEU A 133
HIS A  72
TRP A  73
ASP A 149
None
0.90A 3wg7C-3e0jA:
undetectable
3wg7N-3e0jA:
undetectable
3wg7P-3e0jA:
undetectable
3wg7C-3e0jA:
18.12
3wg7N-3e0jA:
22.05
3wg7P-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 7 THR A 320
LEU A 327
VAL A 294
VAL A 276
ASP A 280
None
1.36A 3wrhA-3e0jA:
undetectable
3wrhA-3e0jA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 7 THR A 320
LEU A 327
VAL A 294
VAL A 276
ASP A 280
None
1.36A 3wrjA-3e0jA:
undetectable
3wrjA-3e0jA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 7 THR A 320
LEU A 327
VAL A 294
VAL A 276
ASP A 280
None
1.36A 3wrlA-3e0jA:
undetectable
3wrlA-3e0jA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 7 THR A 320
LEU A 327
VAL A 294
VAL A 276
ASP A 280
None
1.38A 3wrlE-3e0jA:
undetectable
3wrlE-3e0jA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 7 THR A 320
LEU A 327
VAL A 294
VAL A 276
ASP A 280
None
1.35A 3wrmA-3e0jA:
undetectable
3wrmA-3e0jA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 7 THR A 320
LEU A 327
VAL A 294
VAL A 276
ASP A 280
None
1.38A 3wrmF-3e0jA:
undetectable
3wrmF-3e0jA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.88A 3x2qA-3e0jA:
undetectable
3x2qC-3e0jA:
undetectable
3x2qP-3e0jA:
undetectable
3x2qA-3e0jA:
22.05
3x2qC-3e0jA:
18.12
3x2qP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 LEU A 133
HIS A  72
TRP A  73
ASP A 149
None
0.85A 3x2qC-3e0jA:
undetectable
3x2qN-3e0jA:
undetectable
3x2qP-3e0jA:
undetectable
3x2qC-3e0jA:
18.12
3x2qN-3e0jA:
22.05
3x2qP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC0_A_MIYA1204_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS B FROM
TRANSPOSON TN1 0)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2
DNA POLYMERASE
SUBUNIT DELTA-3

(Homo
sapiens)
5 / 12 ASN A  21
THR A  12
LEU A  13
GLN B  39
LEU B  41
None
1.32A 4ac0A-3e0jA:
undetectable
4ac0A-3e0jA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_D_RAPD201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
SERINE/THREONINE-PRO
TEIN KINASE MTOR)
3e0j DNA POLYMERASE
SUBUNIT DELTA-3

(Homo
sapiens)
5 / 9 LEU B 126
SER B 124
THR B 117
ASP B 118
TYR B  28
None
1.46A 4drhE-3e0jB:
undetectable
4drhE-3e0jB:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)
3e0j DNA POLYMERASE
SUBUNIT DELTA-3

(Homo
sapiens)
5 / 8 LEU B 126
SER B 124
THR B 117
ASP B 118
TYR B  28
None
1.40A 4drjB-3e0jB:
undetectable
4drjB-3e0jB:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 ASN A 348
GLN A 347
GLY A 346
SER A 345
None
0.70A 4f93B-3e0jA:
undetectable
4f93B-3e0jA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
3 / 3 ARG A  57
HIS A 373
TYR A  54
None
1.29A 4fu8A-3e0jA:
undetectable
4fu8A-3e0jA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
3 / 3 ARG A  57
HIS A 373
TYR A  54
None
1.27A 4fu9A-3e0jA:
undetectable
4fu9A-3e0jA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
3 / 3 PHE A 452
VAL A 221
GLU A 231
None
0.80A 4fvqA-3e0jA:
undetectable
4fvqA-3e0jA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 5 THR A 344
GLY A 405
VAL A 428
TYR A 402
None
1.03A 4grkA-3e0jA:
undetectable
4grkA-3e0jA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 11 ALA A 244
GLN A 308
PRO A 392
PHE A 393
ILE A 374
None
1.40A 4j4vA-3e0jA:
undetectable
4j4vA-3e0jA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 7 THR A 320
VAL A 294
VAL A 276
ASP A 280
None
1.05A 4l4gA-3e0jA:
undetectable
4l4gA-3e0jA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 12 PHE A 410
VAL A 426
GLY A 411
LEU A 424
SER A 444
None
1.44A 4ot2A-3e0jA:
undetectable
4ot2A-3e0jA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 10 LEU A 283
VAL A 199
LEU A 197
LEU A 218
VAL A 222
None
1.19A 4po0A-3e0jA:
undetectable
4po0A-3e0jA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.89A 5b1aA-3e0jA:
undetectable
5b1aC-3e0jA:
undetectable
5b1aP-3e0jA:
undetectable
5b1aA-3e0jA:
22.05
5b1aC-3e0jA:
18.12
5b1aP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.92A 5b1bA-3e0jA:
undetectable
5b1bC-3e0jA:
undetectable
5b1bP-3e0jA:
undetectable
5b1bA-3e0jA:
22.05
5b1bC-3e0jA:
18.12
5b1bP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.91A 5b3sA-3e0jA:
undetectable
5b3sC-3e0jA:
undetectable
5b3sP-3e0jA:
undetectable
5b3sA-3e0jA:
22.05
5b3sC-3e0jA:
18.12
5b3sP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 LEU A 133
HIS A  72
TRP A  73
ASP A 149
None
0.92A 5iy5C-3e0jA:
undetectable
5iy5N-3e0jA:
undetectable
5iy5P-3e0jA:
undetectable
5iy5C-3e0jA:
17.92
5iy5N-3e0jA:
22.05
5iy5P-3e0jA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-3

(Homo
sapiens)
4 / 8 ASP B 118
THR B 117
VAL B  34
TYR B  23
None
1.17A 5ov9B-3e0jB:
undetectable
5ov9B-3e0jB:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
3 / 3 PHE A 353
ASP A 351
LEU A 369
None
0.76A 5uhbC-3e0jA:
undetectable
5uhbC-3e0jA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHC_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
3 / 3 PHE A 353
ASP A 351
LEU A 369
None
0.65A 5uhcC-3e0jA:
undetectable
5uhcC-3e0jA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)
3e0j DNA POLYMERASE
SUBUNIT DELTA-3

(Homo
sapiens)
4 / 7 LEU B 114
VAL B  45
TYR B  61
GLU B  82
None
1.31A 5umwA-3e0jB:
undetectable
5umwF-3e0jB:
undetectable
5umwA-3e0jB:
14.48
5umwF-3e0jB:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2
DNA POLYMERASE
SUBUNIT DELTA-3

(Homo
sapiens;
Homo
sapiens)
4 / 4 LEU A 226
GLY A 227
SER B  97
SER B  64
None
1.23A 5uunA-3e0jA:
undetectable
5uunA-3e0jA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2
DNA POLYMERASE
SUBUNIT DELTA-3

(Homo
sapiens;
Homo
sapiens)
4 / 4 LEU A 226
GLY A 227
SER B  97
SER B  64
None
1.23A 5uunB-3e0jA:
undetectable
5uunB-3e0jA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.85A 5w97A-3e0jA:
undetectable
5w97C-3e0jA:
undetectable
5w97c-3e0jA:
undetectable
5w97A-3e0jA:
22.05
5w97C-3e0jA:
18.12
5w97c-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.82A 5wauA-3e0jA:
undetectable
5wauC-3e0jA:
undetectable
5wauc-3e0jA:
undetectable
5wauA-3e0jA:
22.05
5wauC-3e0jA:
18.12
5wauc-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.91A 5x19A-3e0jA:
undetectable
5x19C-3e0jA:
undetectable
5x19P-3e0jA:
undetectable
5x19A-3e0jA:
22.05
5x19C-3e0jA:
18.12
5x19P-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.91A 5xdqA-3e0jA:
undetectable
5xdqC-3e0jA:
undetectable
5xdqP-3e0jA:
undetectable
5xdqA-3e0jA:
22.05
5xdqC-3e0jA:
18.12
5xdqP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 LEU A 133
HIS A  72
TRP A  73
ASP A 149
None
0.89A 5xdqC-3e0jA:
undetectable
5xdqN-3e0jA:
undetectable
5xdqP-3e0jA:
undetectable
5xdqC-3e0jA:
18.12
5xdqN-3e0jA:
22.05
5xdqP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 LEU A 133
HIS A  72
TRP A  73
ASP A 149
None
0.87A 5xdxC-3e0jA:
undetectable
5xdxN-3e0jA:
undetectable
5xdxP-3e0jA:
undetectable
5xdxC-3e0jA:
18.12
5xdxN-3e0jA:
22.05
5xdxP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.88A 5z84A-3e0jA:
undetectable
5z84C-3e0jA:
undetectable
5z84P-3e0jA:
undetectable
5z84A-3e0jA:
22.05
5z84C-3e0jA:
18.12
5z84P-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.89A 5z85A-3e0jA:
undetectable
5z85C-3e0jA:
undetectable
5z85P-3e0jA:
undetectable
5z85A-3e0jA:
22.05
5z85C-3e0jA:
18.12
5z85P-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.89A 5z86A-3e0jA:
undetectable
5z86C-3e0jA:
undetectable
5z86P-3e0jA:
undetectable
5z86A-3e0jA:
22.05
5z86C-3e0jA:
18.12
5z86P-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 LEU A 133
HIS A  72
TRP A  73
ASP A 149
None
0.90A 5z86C-3e0jA:
undetectable
5z86N-3e0jA:
undetectable
5z86P-3e0jA:
undetectable
5z86C-3e0jA:
18.12
5z86N-3e0jA:
22.05
5z86P-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.90A 5zcoA-3e0jA:
undetectable
5zcoC-3e0jA:
undetectable
5zcoP-3e0jA:
undetectable
5zcoA-3e0jA:
22.05
5zcoC-3e0jA:
18.12
5zcoP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 LEU A 133
HIS A  72
TRP A  73
ASP A 149
None
0.91A 5zcoC-3e0jA:
undetectable
5zcoN-3e0jA:
undetectable
5zcoP-3e0jA:
undetectable
5zcoC-3e0jA:
18.12
5zcoN-3e0jA:
22.05
5zcoP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.88A 5zcpA-3e0jA:
undetectable
5zcpC-3e0jA:
undetectable
5zcpP-3e0jA:
undetectable
5zcpA-3e0jA:
22.05
5zcpC-3e0jA:
18.12
5zcpP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 LEU A 133
HIS A  72
TRP A  73
ASP A 149
None
0.92A 5zcpC-3e0jA:
undetectable
5zcpN-3e0jA:
undetectable
5zcpP-3e0jA:
undetectable
5zcpC-3e0jA:
18.12
5zcpN-3e0jA:
22.05
5zcpP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 HIS A  72
TRP A  73
ASP A 149
LEU A 133
None
0.90A 5zcqA-3e0jA:
undetectable
5zcqC-3e0jA:
undetectable
5zcqP-3e0jA:
undetectable
5zcqA-3e0jA:
22.05
5zcqC-3e0jA:
18.12
5zcqP-3e0jA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 12 VAL A 428
GLY A 405
SER A 345
PHE A 403
VAL A 241
None
1.44A 6a94A-3e0jA:
undetectable
6a94A-3e0jA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
5 / 12 PHE A 410
VAL A 426
GLY A 411
LEU A 424
SER A 444
None
1.43A 6ci6A-3e0jA:
undetectable
6ci6A-3e0jA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo
sapiens)
4 / 8 LEU A 133
HIS A  72
TRP A  73
ASP A 149
None
0.86A 6nknC-3e0jA:
undetectable
6nknN-3e0jA:
undetectable
6nknP-3e0jA:
undetectable
6nknC-3e0jA:
18.12
6nknN-3e0jA:
22.05
6nknP-3e0jA:
18.12