SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e0r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)
(Streptococcus
pneumoniae) 		4 / 7 ILE A 169
PHE A 198
PHE A 238
PHE A 212
 None
 1.17A 1e71M-3e0rA:
undetectable		 1e71M-3e0rA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)
(Streptococcus
pneumoniae) 		4 / 7 ILE A 169
PHE A 198
PHE A 238
PHE A 212
 None
 1.17A 1e72M-3e0rA:
undetectable		 1e72M-3e0rA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)
(Streptococcus
pneumoniae) 		5 / 12 ALA A  72
LEU A 193
ILE A 150
LEU A  52
ILE A 116
 None
 1.02A 1rx7A-3e0rA:
undetectable		 1rx7A-3e0rA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)
(Streptococcus
pneumoniae) 		4 / 5 PHE A 238
LEU A 164
PHE A 226
SER A 214
 None
 1.23A 1wrkB-3e0rA:
undetectable		 1wrkB-3e0rA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)
(Streptococcus
pneumoniae) 		4 / 8 LYS A  99
TYR A 104
PRO A 134
LEU A  88
 None
 0.98A 1z2bB-3e0rA:
undetectable		 1z2bB-3e0rA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)
(Streptococcus
pneumoniae) 		3 / 3 PHE A 238
GLN A   5
PHE A 212
 None
 0.80A 3rv5A-3e0rA:
undetectable		 3rv5A-3e0rA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)
(Streptococcus
pneumoniae) 		5 / 11 ALA A  72
LEU A 193
ILE A 150
LEU A  52
ILE A 116
 None
 1.08A 3tqbA-3e0rA:
undetectable		 3tqbA-3e0rA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)
(Streptococcus
pneumoniae) 		5 / 12 ALA A  72
LEU A 193
ILE A 150
LEU A  52
ILE A 116
 None
 1.14A 4nx6A-3e0rA:
undetectable		 4nx6A-3e0rA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)
(Streptococcus
pneumoniae) 		5 / 12 ALA A  72
LEU A 193
ILE A 150
LEU A  52
ILE A 116
 None
 1.11A 4pstA-3e0rA:
undetectable		 4pstA-3e0rA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)
(Streptococcus
pneumoniae) 		4 / 6 LYS A  99
TYR A 104
PRO A 134
LEU A  88
 None
 0.98A 5bmvB-3e0rA:
undetectable		 5bmvB-3e0rA:
19.27