SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e0s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 5 LEU A 453
THR A 454
ARG A 491
VAL A 494
 None
 1.04A 1ekjF-3e0sA:
undetectable
1ekjG-3e0sA:
undetectable		 1ekjF-3e0sA:
20.54
1ekjG-3e0sA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 PHE A 255
TYR A 347
MET A 351
THR A 352
 None
 0.93A 1v55N-3e0sA:
1.4
1v55W-3e0sA:
undetectable		 1v55N-3e0sA:
19.13
1v55W-3e0sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		3 / 3 ASP A 254
GLU A 422
ARG A 411
 None
 0.88A 1wopA-3e0sA:
undetectable		 1wopA-3e0sA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		3 / 3 ASP A 330
GLU A 476
TYR A 308
 None
 0.78A 1wsvA-3e0sA:
undetectable		 1wsvA-3e0sA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 ARG A 267
LEU A 229
ILE A 412
ASP A 413
LEU A 268
 None
 1.17A 2zzmA-3e0sA:
undetectable		 2zzmA-3e0sA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 PHE A 255
TYR A 347
MET A 351
THR A 352
 None
 0.89A 3abkA-3e0sA:
2.9
3abkJ-3e0sA:
undetectable		 3abkA-3e0sA:
19.13
3abkJ-3e0sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 PHE A 255
TYR A 347
MET A 351
THR A 352
 None
 0.89A 3abmN-3e0sA:
2.9
3abmW-3e0sA:
undetectable		 3abmN-3e0sA:
19.13
3abmW-3e0sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 PHE A 255
TYR A 347
MET A 351
THR A 352
 None
 0.91A 3ag2N-3e0sA:
1.1
3ag2W-3e0sA:
undetectable		 3ag2N-3e0sA:
19.13
3ag2W-3e0sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 5 PHE A 424
PHE A 428
LEU A 517
PHE A 514
 None
 1.27A 3ag3C-3e0sA:
5.2
3ag3J-3e0sA:
undetectable		 3ag3C-3e0sA:
22.84
3ag3J-3e0sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 PHE A 255
TYR A 347
MET A 351
THR A 352
 None
 0.92A 3ag3N-3e0sA:
1.5
3ag3W-3e0sA:
undetectable		 3ag3N-3e0sA:
19.13
3ag3W-3e0sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 PHE A 255
TYR A 347
MET A 351
THR A 352
 None
 0.92A 3ag4N-3e0sA:
1.1
3ag4W-3e0sA:
undetectable		 3ag4N-3e0sA:
19.13
3ag4W-3e0sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 PHE A 255
TYR A 347
MET A 351
THR A 352
 None
 0.92A 3asoN-3e0sA:
undetectable
3asoW-3e0sA:
undetectable		 3asoN-3e0sA:
19.13
3asoW-3e0sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		5 / 10 ALA A 432
ALA A 380
ILE A 384
LEU A 417
PHE A 514
 None
 1.21A 3fl9A-3e0sA:
undetectable		 3fl9A-3e0sA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 4 LEU A 443
SER A 503
LEU A 392
LEU A 447
 None
 1.04A 4n09A-3e0sA:
undetectable		 4n09A-3e0sA:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 GLU A 406
LEU A 410
LEU A 447
LEU A 443
 None
 0.79A 4wg0B-3e0sA:
undetectable
4wg0C-3e0sA:
undetectable		 4wg0B-3e0sA:
4.29
4wg0C-3e0sA:
4.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 LEU A 447
LEU A 443
GLU A 406
LEU A 410
 None
 0.78A 4wg0L-3e0sA:
undetectable
4wg0M-3e0sA:
undetectable		 4wg0L-3e0sA:
4.29
4wg0M-3e0sA:
4.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 PHE A 255
TYR A 347
MET A 351
THR A 352
 None
 0.92A 5b1bN-3e0sA:
2.9
5b1bW-3e0sA:
undetectable		 5b1bN-3e0sA:
19.13
5b1bW-3e0sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 PHE A 255
TYR A 347
MET A 351
THR A 352
 None
 0.93A 5b3sN-3e0sA:
1.4
5b3sW-3e0sA:
undetectable		 5b3sN-3e0sA:
19.13
5b3sW-3e0sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		3 / 3 SER A 264
LEU A 354
MET A 281
 None
 0.75A 5ikrB-3e0sA:
0.4		 5ikrB-3e0sA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 PHE A 255
TYR A 347
MET A 351
THR A 352
 None
 0.94A 5iy5N-3e0sA:
2.2
5iy5W-3e0sA:
undetectable		 5iy5N-3e0sA:
19.13
5iy5W-3e0sA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		3 / 3 VAL A 379
HIS A 222
VAL A 225
 None
 0.55A 5jmnC-3e0sA:
2.2		 5jmnC-3e0sA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 5 PHE A 424
PHE A 428
LEU A 517
PHE A 514
 None
 1.29A 5wauC-3e0sA:
4.5
5wauJ-3e0sA:
undetectable		 5wauC-3e0sA:
22.84
5wauJ-3e0sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 5 PHE A 424
PHE A 428
LEU A 517
PHE A 514
 None
 1.30A 5wauc-3e0sA:
4.5
5wauj-3e0sA:
undetectable		 5wauc-3e0sA:
22.84
5wauj-3e0sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 5 PHE A 424
PHE A 428
LEU A 517
PHE A 514
 None
 1.20A 5xdqC-3e0sA:
4.7
5xdqJ-3e0sA:
undetectable		 5xdqC-3e0sA:
22.84
5xdqJ-3e0sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 5 PHE A 424
PHE A 428
LEU A 517
PHE A 514
 None
 1.24A 5xdqP-3e0sA:
4.6
5xdqW-3e0sA:
undetectable		 5xdqP-3e0sA:
22.84
5xdqW-3e0sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3e0s UNCHARACTERIZED
PROTEIN
(Chlorobaculum
tepidum) 		4 / 8 PHE A 255
TYR A 347
MET A 351
THR A 352
 None
 0.93A 5zcpN-3e0sA:
3.0
5zcpW-3e0sA:
undetectable		 5zcpN-3e0sA:
19.13
5zcpW-3e0sA:
10.43