SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e19'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 3e19 FEOA
(Thermococcus
thioreducens) 		5 / 12 GLY A  39
VAL A  72
SER A  56
LEU A  77
LEU A   7
 None
 1.02A 1ya4C-3e19A:
undetectable		 1ya4C-3e19A:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3e19 FEOA
(Thermococcus
thioreducens) 		5 / 10 ILE A  53
ILE A  55
GLY A  35
VAL A  74
LEU A  68
 None
 1.18A 3em0A-3e19A:
undetectable		 3em0A-3e19A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3e19 FEOA
(Thermococcus
thioreducens) 		5 / 12 MET A  34
LEU A  36
ILE A  55
ILE A  53
LEU A  68
 None
 1.15A 4j24A-3e19A:
undetectable		 4j24A-3e19A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3e19 FEOA
(Thermococcus
thioreducens) 		5 / 12 MET A  34
LEU A  36
ILE A  55
ILE A  53
LEU A  68
 None
 1.15A 4j24B-3e19A:
undetectable		 4j24B-3e19A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 3e19 FEOA
(Thermococcus
thioreducens) 		4 / 7 VAL A  74
VAL A  72
ILE A  64
ILE A  55
 None
 0.78A 5ywmX-3e19A:
undetectable		 5ywmX-3e19A:
24.10