SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3e1e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3e1e THIOESTERASE FAMILY
PROTEIN
(Ruegeria
pomeroyi) 		5 / 10 ALA A 116
THR A 115
ALA A 114
ALA A 102
ASP A  63
 None
 0.93A 2f16K-3e1eA:
undetectable
2f16L-3e1eA:
undetectable		 2f16K-3e1eA:
19.91
2f16L-3e1eA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3e1e THIOESTERASE FAMILY
PROTEIN
(Ruegeria
pomeroyi) 		5 / 10 ALA A 116
THR A 115
ALA A 114
ALA A 102
ASP A  63
 None
 0.91A 2f16Y-3e1eA:
undetectable
2f16Z-3e1eA:
undetectable		 2f16Y-3e1eA:
19.91
2f16Z-3e1eA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3e1e THIOESTERASE FAMILY
PROTEIN
(Ruegeria
pomeroyi) 		5 / 12 ALA A 116
THR A 115
ALA A 114
ALA A 102
ASP A  63
 None
 0.88A 3mg0Y-3e1eA:
undetectable
3mg0Z-3e1eA:
undetectable		 3mg0Y-3e1eA:
19.91
3mg0Z-3e1eA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3e1e THIOESTERASE FAMILY
PROTEIN
(Ruegeria
pomeroyi) 		5 / 10 ALA A 116
THR A 115
ALA A 114
ALA A 102
ASP A  63
 None
 1.01A 4qvyK-3e1eA:
undetectable
4qvyL-3e1eA:
undetectable		 4qvyK-3e1eA:
19.91
4qvyL-3e1eA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3e1e THIOESTERASE FAMILY
PROTEIN
(Ruegeria
pomeroyi) 		5 / 10 ALA A 116
THR A 115
ALA A 114
ALA A 102
ASP A  63
 None
 1.02A 4qvyY-3e1eA:
undetectable
4qvyZ-3e1eA:
undetectable		 4qvyY-3e1eA:
19.91
4qvyZ-3e1eA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3e1e THIOESTERASE FAMILY
PROTEIN
(Ruegeria
pomeroyi) 		5 / 9 ALA A 114
THR A 115
ALA A 116
GLY A  34
ALA A  70
 None
 1.07A 5l5zK-3e1eA:
undetectable
5l5zL-3e1eA:
undetectable		 5l5zK-3e1eA:
18.06
5l5zL-3e1eA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3e1e THIOESTERASE FAMILY
PROTEIN
(Ruegeria
pomeroyi) 		5 / 9 ALA A 116
THR A 115
ALA A 114
ALA A 102
ASP A  63
 None
 1.04A 5l5zK-3e1eA:
undetectable
5l5zL-3e1eA:
undetectable		 5l5zK-3e1eA:
18.06
5l5zL-3e1eA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3e1e THIOESTERASE FAMILY
PROTEIN
(Ruegeria
pomeroyi) 		5 / 9 ALA A 114
THR A 115
ALA A 116
GLY A  34
ALA A  70
 None
 1.07A 5l5zY-3e1eA:
undetectable
5l5zZ-3e1eA:
undetectable		 5l5zY-3e1eA:
18.06
5l5zZ-3e1eA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3e1e THIOESTERASE FAMILY
PROTEIN
(Ruegeria
pomeroyi) 		5 / 9 ALA A 116
THR A 115
ALA A 114
ALA A 102
ASP A  63
 None
 1.03A 5l5zY-3e1eA:
undetectable
5l5zZ-3e1eA:
undetectable		 5l5zY-3e1eA:
18.06
5l5zZ-3e1eA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3e1e THIOESTERASE FAMILY
PROTEIN
(Ruegeria
pomeroyi) 		6 / 12 GLY A  67
PHE A  15
VAL A  11
SER A  64
ALA A  65
ALA A 116
 None
 1.50A 5n0oB-3e1eA:
undetectable		 5n0oB-3e1eA:
16.54